Im sorry you're having such a hard time with Byetta, but if you're still violently ill to the point of being nearly bed ridden after two weeks on 5mcg, perhaps Byetta just isn't for you. There are lots of powerful oral meds that you can and should begin taking (eg. Avandia, Glipizide, Starlix, etc.) that can do wonders with pulling your BS back into a normal range. If that doesn't do it there is always the once a day shot of Lantus insulin. This is no big deal in that you don't even feel the shot and one shot supplies you a constant base dose of insulin all day long from which your oral meds can work. This might be a much better route for you than the suffering you are going through with Byetta.
Talk to your Endocrinologist and tell him specifically about how sick you have been and what your numbers have been doing.
Glipizide and Metformin are two very different types of meds. The metformin basically works to break down your insulin resistence and make you more sensitive to insulin while the Glipizide prods your pancreas to release more insulin. If I take to much glipizide with my Byetta, I acutally can go to low, its that effective!
LOLOL I've never been excited about a doctors appointment. Yes, Lex, you are insulin resistent. The metformin is the first drug usually prescribed for this and it is specifically to make you more sensitive to the insulin you are already producing. This coupled with the Byetta and you have a very nice combination. Metformin seems to be one of those drugs, however, that seems to quit working sooner or later in type 2 diabetics. So if your numbers were really high on just the metformin, thats not surprising.
Tell your doctor you would like a drug like "glipizide" to augment the byetta and help pull your numbers down farther. Eventually, if you can move to the 10mcg dose of Byetta, you might be able to get rid of this extra drug alltogether, but for now, we aren't even going to think about a stronger dose of Byetta as you have been having such a tough time! Let us know what the doctor says and lets get your numbers into a zone that will make you smile after each finger stick!