allow me to deviate a little from B vitamins to C vitamin(Ascorbic acid).
Vitamin C (Ascorbic Acid). Ascorbic acid is needed for proper white cell function and wound healing. Hyperglycemia and oxidative stress adversely affect leukocyte(White cell) function. Leukocyte ascorbate levels may be reduced by oxidative stress. Ascorbic acid improves endothelial-dependent vasodilatation.
Hyperglycemia increases urinary losses of ascorbate. This may explain why diabetic patients have low levels of ascorbic acid Low levels of ascorbic acid may make the diabetic patient more susceptible to wound infection, delayed healing, endothelial dysfunction . Therefore, diabetic patients who are not controlled require greater amounts of ascorbic acid in their diet.
The normal amount to provide antioxidant protection (recommended dietary allowance) is 90 mg and 75 mg for men and women, respectively, and is based on the minimal urinary excretion of ascorbate. Smoking increased the requirement by 35 mg/day.Hyperglycemia should increase the requirement by as much as smoking, if not more. Providing the diabetic patient with enough ascorbic acid to cover losses in the urine is the central point.
The upper tolerable limit is 2 g. The daily requirement of ascorbic acid should be increased to 200 mg daily in Diabetics. Smokers should have an additional 50 mg of ascorbic acid in their diet.
I hope we all check how much C vitamin we are taking.75 to 90 mgs in a day as a supplement is absolutely a sub-optimal dose is the message i wish to convey!