Unfortunately, Byetta in its early stages is almost guaranteed to make you nauseous! maybe not so much on 5mg but the 10mg really does it to most people. If your social life is such that you can't give it up to adjust to a new drug, talk to your doctor about using Januvia instead. It is a drug very much like Byetta without any of the nasty side effects. It doesn't appear to be AS EFFECTIVE, but it still far more effictive than orals alone! Me? I'd temporarily suspend my social life for the benefits of Byetta, but everyone has their own agenda.