Cymbalta and Lyrica Together

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Veteran Member

Date Joined Jun 2008
Total Posts : 844
   Posted 8/26/2008 4:35 PM (GMT -7)   
Today I went back for my second visit to my rheumy and she told me to keep taking my Lyrica and then put me on Cymbalta too.  I haven't read about anyone taking them both.  Of course I take a low dosage of Lyrica. 
Does anyone out there take them both?
God Bless!
Of all the things that I have lost, I miss my mind the most!!!!

Sera Smiles
Veteran Member

Date Joined Nov 2006
Total Posts : 669
   Posted 8/27/2008 1:28 AM (GMT -7)   
I have heard of people on this forum taking both, but it suprises me a little. I say if it helps, if it works, more power to ya! I look forward to hearing what others have to say on this topic. Shannon, are you taking them both yet? Any thoughts?
DX- FMS 2003; Hypertension; Depression; PTSD; IBS
RX- Ultram 100mg x 2/d; Toprol 100mg/d; Cymbalta 60mg/d; Buspar 5mg x 2/d;  Malic / Magn 1650/300 x 2/d; Claritin 10mg/d; Bendryl 50mg x 2/d;
B-Complex 1/d; Melatonin 5mg/night; Ginseng 500mg x 2/d
PRN- Flexeril 10mg; Hyoscine Butyl 2 mg
"Its never too late to be who you might have been" George Eliot

Veteran Member

Date Joined Jun 2008
Total Posts : 844
   Posted 8/27/2008 5:29 AM (GMT -7)   
I took them both about 3 hours before bedtime and I never closed my eyes for sleep until about 3:30 this morning.  I think the Cymbalta is supposed to help me more on my energy level too.  That might be why I couldn't sleep.  Also every time I turned over it made me sick at my stomach.  I don't know whether to take it of the morning or not, because I have to go to work.  It did take away my pain though.  When I went to bed my right hand was aching really bad and it eased it down in just a little bit.
I'm anxious to hear what others think about taking them both.  I don't know if I want to continue this therapy or not.
God Bless!
Of all the things that I have lost, I miss my mind the most!!!!

Regular Member

Date Joined Jul 2008
Total Posts : 64
   Posted 8/27/2008 6:15 AM (GMT -7)   
I would definitly take the Cymbalta in the morning and with food. I am liking it but when it interferes with sleep, the bad outweigh the good. I took my dose, 60 mg. at 6:30 this morning to see if that helps with sleep tonight. Ofcourse I could only do this because I had a pop tart and dried apricots by the bed and could reach my cym and my adderall. If my sleep doesn't improve, I'm going to cut my dose down to 40 mg. For four days, i had nausea, tremors, anxiety, dizziness, and light headedness but it went away. I think it is causing mild acne and worsening my insomnia but I'm going to hang in there with it. I got really depressed a few weeks ago and felt really disconnected from my four year old son and had some vicious fights with my husband. My mood has improved but I am still irritable and not nearly as patient as I used to be.

Regular Member

Date Joined Feb 2008
Total Posts : 278
   Posted 8/27/2008 6:40 AM (GMT -7)   

I had been taking both Cymbalta and Lyrica for some time. I took the cymbalta in the morning and the Lyrica in the morning and at bedtime.

I just recently quit the Lyrica because I was tired of the grogginess. I have no more pain without the Lyrica than when I was taking it.


Fibro is a life sentence, but not a death sentence.
Fibro since 2005
Lyrica, Cymbalta, Trazadone

Regular Member

Date Joined Jun 2008
Total Posts : 44
   Posted 8/27/2008 8:10 AM (GMT -7)   
I've been taking Lyrica and Cymbalta together for about a year. The Cymbalta has to be taken first thing in the morning. I take 300mg of Lyrica 2x a day. I went to my rheumatologist about 10 days ago and since spring have been having more depression and fatigue. The doctor increased my Cymbalta dosage from 60mg to 120mg. I was a little concerned about the large dosage but it has greatly helped my fatigue and stress. I am able to relax and enjoy my life a bit, and isn't that what life is all about?
As for the Lyrica helping pain, for me it just seems to help with the burning type of pain-but not the aching. I have burning in both of my hamstrings which are very tight-the Lyrica is the only thing that relieves it at all. At first, it made me a little dizzy, but now it doesn't bother me.
I take xanex to sleep at night and I go right to sleep, but since the increase in Cymbalta I haven't slept as sound. But before the increase I was so tired all the time that I barely had enough energy to do anything. I guess I'll try it for awhile and see what happens!
mother of four sons, grandma to five, wife to one wonderful husband
fibromyalgia since 1993
Cymbalta, Tramadol, Lyrica, Xanex
 Love people and use things NOT love things and use people.
 He is richest who is content with the least....Socrates

Regular Member

Date Joined Jan 2005
Total Posts : 249
   Posted 8/27/2008 10:03 AM (GMT -7)   
I took both for a while too. If you don't take the Cymbalta very early, it can interfere with sleep. I take mine at about 6:30 am. The doctor took me off the Lyrica because it was making my vision very blurry. That caused me horrible withdrawal symptoms for over a week, and now he has me on the Cymbalta in the morning and Amrix in the evenings. I just started taking the Amrix yesterday, so I don't know if it will work longterm but I hope so.

New Member

Date Joined Jul 2011
Total Posts : 1
   Posted 7/19/2011 8:13 PM (GMT -7)   
My Doctor just put me on Lyrica, I have taken Cymbalta for a few years. Recently the burning pain has been unbearable, I sure hope this helps. I also, take Ambien to sleep because of the pain. If anyone can offer any help I would appreciate it.

The Cymbalta does give you dry eyes if you haven't experienced it yet be prepared.

New Member

Date Joined Jul 2011
Total Posts : 14
   Posted 7/20/2011 9:01 PM (GMT -7)   
I have been taking Cymbalta for depression for awhile for depression and was just put on Lyrica. I take the Cymbalta in the morning and the Lyrica at bedtime. No problems so far.

Regular Member

Date Joined Jul 2011
Total Posts : 76
   Posted 7/21/2011 1:38 PM (GMT -7)   
I don' know about Lyrica, but I have been on Cymbalta for about 3 years. I take it at night. It makes some drowsy and others it doesn't. You can take it in the morning if it bothers your sleep. Also, I had nausea and sometimes headaches for the first week or so....but later that got better. I was on it for a while and didn't think it was working so I tried weaning off of it. Found out fast, it worked better than I thought. Hope it helps.
New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, November 28, 2015 2:03 PM (GMT -7)
There are a total of 2,542,129 posts in 280,981 threads.
View Active Threads

Who's Online
This forum has 150138 registered members. Please welcome our newest member, Lionsden.
306 Guest(s), 11 Registered Member(s) are currently online.  Details
Celeste15, 81GyGuy, wayup, floridadude23, dusty8105, Daxter, charlotte91, SueCAll, Cdavislyme, LymiesBrother, iPoop

Follow on Facebook  Follow on Twitter  Follow on Pinterest  Follow on YouTube

©1996-2015 LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer