Hi Lisa and welcome. I have not had any experience with methadone or lyrica. We have a great group of people here that are always willing to help. Read the fibro 101 thread, second on first page, it contains lots of info. Read as much as you can on the threads and ask questions and you will learn what works and doesn't work for you. With fibro it's all trial and error to find what gives relief.
luv and hugs
Forum Moderator Fibromyalgia
Fibro,Sjogrens, Anxiety, Gastroparesis, IBS, Gastritis, Allergies, High Blood Pressure, Low Blood Sodium and Osteoarthritis
Amitriptyline, Celexa, Xanax, Synthroid, Zyrtec, Micardis, Spironalactone, Tylenol, Reglan, Lidoderm Patches and Tramadol
Co Q 10, Super B Complex, Extra B12, Multi vitamin