There's something to that theory of Fibromites struggling to obtain levels of serotonin to function. I was on Zoloft for about 8 years. Then it just seemed to not work. They tried a few other, luvox, and one other (only cause I had no drug plan and Doc had samples, and I didn't notice any effect, whatsoever. i wandered around for a couple of years with nothing but amyl for sleep and pain meds cause I wasn't getting the restful sleep I needed. I knew it had to do with Serotonin levels but couldn't quite figure what to do.
Then once back in Canada with socialized medicine and a safty net for keeping people off the streets (just barely), I have all the meds I need to function in the limited fashion, as I do. Up for three hours, down for two, up for four or so, down for the night (in winter). Summer I have less pain and stiffness so I'm more active.