Effexor is a seratonin and norepinephrine reuptake inhibitor. A couple of years ago I took effexor for depression and it was fine unless I forgot to take a pill. Then I felt like I was breathing carbon monoxide while driving on a winding road. I decided that it is dumb for me to take a med that makes me feel so horrible when I forget. I could not get off of it alone - I had to take prozac in small doses and decrease the effexor slowly in order to get off it without feeling rotten. If you don't think you will forget and you don't plan to go off of it, I guess it is ok. I prefer prozac if something is needed. Now I don't take anything (except mobic and zanaflex). For me, that is better.