Hello again everybody!
Thank you for all your warm and caring responses to my "Reconnect" thread! Some of you mentioned there that you had never heard of this particular treatment regimen before. I thought it would be helpful to those to provide a little more info and some links to some in-depth articles that mention this treatment option amongst many others. As with any treatment option, there is no guarantee this will work for everybody but you can definitely count me as a true-blue believer in it's results! So sorry if this is rather long.
First is a declaration from another patient using this regimen and I can echo her sentiments:
My Treatment Plan Involving Glutothion/Adenosine Triphosphate InjectionsHello to everyone!! I want to share the treatment plan I am currently on for CFS/FMS, because it is rather unusual (I think...) I am seeing a terrific doctor who is a self proclaimed fibromyalgia and chronic fatigue syndrome expert. I found my doctor by reading a book called "Living Well With Chronic Fatigue Syndrome and Fibromyalgia," by Mary J. Shomon. Ms. Shomon has included a "Resources" section in the back of the book and that is how I found my treating physician. The book can be found at most bookstores or on-line at Amazon.com. My doctor compounds injections which contain a mixture of glutathion and Adenosine triphosphate (ATP). Once I week, I inject 1cc of the Glut/ATP directly into my thigh muscle. I have been doing this for about 18 months and I have made a remarkable improvement in regard to my fibromyalgia and chronic fatigue. My doctor believes that these enzymes (or whatever they are..) stimulates the mitochondria of the cells in the muscles of the body. (If you'd to read more about the cell biology of mitochondria, I have attached the following link http://en.wikipedia.org/wiki/Mitochondrion ). Since I have been taking the injections, I honestly have more good days than bad. I have less pain, my sleep has improved, my energy level has improved and my "Fibro-fog" has improved. I have even stopped the injections for about a month to see what would happen, and I my health took a back-slide. I would be more than happy to send more information to anyone who is interested regarding this treatment method. Stay well!!!
Next is a clip of an article by Dr. Patricia Salvato of Houston who, I understand, developed this treatment (I happen to be fortunate enough to have her as my rheumy). It was originally developed as a treatment for CFS but she found that it works just as well for fibro patients:
A potent antioxidant, glutathione eliminates free radicals, detoxifies and removes heavy metals like lead, mercury and cadmium from the body, recycles oxidized vitamin C back to useful vitamin C, and protects cells from damage from oxidative stress.
A healthy person produces several grams of glutathione daily, but
Dr. Patricia Salvato of Houston, Texas, has found that CFS patients are often deficient. It may help to take magnesium and glutathione together: in a high-quality study in Belgium, patients who were magnesium deficient (47 percent) had significantly lower total antioxidant capacity in their blood. Magnesium deficient patients whose magnesium stores didn’t improve even after oral supplementation with 10 mg magnesium per day also had persistently lower blood glutathione levels.(40)
Recommendation: Have your physician do a whole blood glutathione or glutathione peroxidase test. If they’re low, Dr. Salvato reports that oral glutathione does not enter the cells even taken in massive doses and proposes intramuscular injections instead. Some CFS patients have taken 100 mg. glutathione combined with 1 mg. of ATP injections twice weekly with good results. (In a study of 276 CFIDS patients —218 women and 58 men— who received weekly injections of glutathione/ATP injections, 82 percent (226 patients) reported less fatigue and 196 experienced improvement in memory and concentration, while 171 experienced lower levels of pain. A few patients had heart palpitations thought to have come from the ATP.)
GLUTATHIONE/ATP INJECTIONS PROVIDE RELIEF
Dr. Patricia Salvato of Houston, Texas, reported in The CFIDS Chronicle
( January/â€™February, 1 1998) that she has treated 276 CFIDS patients with injections of glutathione, a small (three amino acid) peptide and adenosine triphosphate (ATP). Both substances are normally found in the body, where glutathione has many important functions, such as detoxification of free radicals and heavy metals. Viruses and other chronic infections deplete the body's store of glutathione. ATP is the key molecule in cellular energy metabolism. Oral glutathione is believed unable to enter the cells, so it was given by injection. ATP was included in the injections to aid in transport of the glutathione into the cell. Eighty-two percent of her patients experienced improvement in their fatigue, while 71 % had improvement in memory and concentration, and 62% had reduced pain. Objective measures such as the Karnovsky Index were used to verify the improvement. Natural killer cell function was also measured, with 187 people showing a two-fold increase. Some patients have received the therapy for as long as 16 months, and the only adverse side effects observed were palpitations in a few patients and a slight rash or itching around the site of injection.
Summarized from the Jan/Feb, 1998. CFIDS Chronicle, published by the CFIDS Association of America. PO Box 22098 Charlotte. NC 28222-0398
Finally, here are some links to some in-depth articles that explain this treatment and others......some of these are rather wordy but worth the read:
If this info ends up helping just one of you I will be forever happy for you!
Gentlest of hugs,
Dx'd June 2008 with Fibro, CFS and CEBV (Chronic Epstein-Barr Virus) after many years of ongoing and worsening symptoms......also, previously dx'd sleep apnea, high blood pressure, hypothyroid, low testosterone, high cholesterol, heart arrythmia & migrane/cluster headaches.
Post Edited (jev) : 3/26/2009 12:13:07 PM (GMT-6)