Blood Test Results ???

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MinnyMouse
Regular Member


Date Joined Jun 2010
Total Posts : 197
   Posted 8/18/2010 3:51 AM (GMT -7)   
Hello everyone and I hope you all are ready for a great day ahead.
I just have a question regarding some blood test results... Lamens language please. I have looked at everythign I can find on the web and just don't get the meaning of any of it.
 
I do see my doctor on Friday so He will be able to answer the questions.
He added Lupus to my list about two months ago.
 
anyway,
 
My ANA was positive again
My sed rate was really high at 59
Vitamin D was low again even though I take 50,000mg a week and and additional 2000 daily. It actually was a little worse this round. I guess I'm not absorbing.
All other tests were within normal range as usual BUT...
 
There was a test within the ANA I don't understand.... the SSA ab was positive but the SSB was negative and all other tests within was negative...Does anyone understand the SSA Ab test results?
 
All I can find is that many autoimmune diseases show high SSA and SSB. It talks about Sjograns as well and looks like that can be a stand alone or with multiple other autoimmune situations.
 
Sjograns looks to have many of the same symptoms as the fibro when it's in a severe form. Have any of you been diagnosed with this. I had not even heard of it before. Sjograns is autoimmune where fibro is not.
 
Just confused... guess the doc will answer all of this on Friday but I can never wait.. LOL impatient...
Anyway, if anyone has information I would appreciate your input.
 
Steph
 
 
 
Savella, Lyrica,Mobic,Tramadol,Flexeril,Omeprezole,Vitamin D3,

sotiredoffibro
Veteran Member


Date Joined May 2010
Total Posts : 1556
   Posted 8/18/2010 5:34 AM (GMT -7)   
Sorry Steph, that stuff is all beyond me too just hoping for you that someone will be able to help you muddle through it.
Gentle Hugs
Shirley
DX: Fibro, Gerds, COPD, Osteoarthritis, Osteoporosis, High Blood Pressure, and Depression.
When I get where Im going dont cry for me down here. (Brad Paisley & Dolly Parton)

crazykitty
Veteran Member


Date Joined Jul 2009
Total Posts : 4796
   Posted 8/18/2010 8:07 AM (GMT -7)   
Steph, what you found is correct. Sjogerns can be associated with some other
autoimmune diseases or it can stand alone as Primary Sjogerns. SJogerns is an
autoimmune disease affecting the tear glands and salivary glands. People who have
it have very dry eyes and mouth. Your doc will monitor any clinical symptoms you
have and do more bloodwork at some point. There are many simularities with the
connective tissue diseases and it takes time to figure it all out. I don't know if you
have enough criteria for a diagnosis. Be sure to make a list of questions for your
doc to bring on Friday. I know how frustrating this all is because I have been through
the process of alot of bloodwork and waiting. Wishing you the best!

Hugs, Robin
Fibromyalgia, MCTD (Lupus, Scleroderma & RA) Raynaud's, Osteoporosis,
Osteoarthritis, Degenerative Disc Disease, Migraines, and Hypertension
Prescription Meds: Savella, Cyclobenzaprine, Methotrexate, Diltiazem, Boniva,
Folic Acid.  OTC Meds: Multi-vitamin. Vit, D, Vitamin B12 & calciim supplements
 
 

JayBespoke
Regular Member


Date Joined Jul 2010
Total Posts : 297
   Posted 8/18/2010 2:23 PM (GMT -7)   
MinnyMouse said...
Hello everyone and I hope you all are ready for a great day ahead.
My ANA was positive again
...
There was a test within the ANA I don't understand.... the SSA ab was positive but the SSB was negative and all other tests within was negative...Does anyone understand the SSA Ab test results?


Hey, I'm not an expert by a long stretch, but I can help a little (hopefully).

http://arthritis.about.com/od/diagnostic/a/ana.htm - "about.com" is very useful whenever I want a simplified explanation of something, and as a starter I've found the entry on ANA. It is an anti-body which is capable of destroying components within a cell (rather than foreign bodies, or whole cells/cell types.

The SSA Antibody is implicated in Sjögren's but also several other autoimmune diseases (including SLE). SSB is far more specific to Sjögren's. What your positive means is that there is a distinct possibility that you have an autoimmune disease, which could potentially be Sjögren's, or something else. This test alone doesn't concern what (if any) condition is present, but is a move in the right direction (for every 100 caucasian males tested with the ANA blood work up, about 5 could be completely healthy.)

The Journal of Translational Immunology has a paper on the clinical significance of SSA, if you would like to know more, though it is obviously quite complex in tone (and me linking to it would break the forum rules.)

Please don't take anything I say as medical advice, it isn't :)

James
21, Male, England.
Dx: Psoriatic Arthritis, Chronic Back Pain, Dyspraxia
Rx: 25mg Methotrexate Sub-Cut Injection & 50mg Etanercept (Enbrel) Sub-Cut Injection

Oh, and plenty of Tramadol, Codeine, Diclofenac, Dihydrocodeine, Paracetamol, Diphenhydramide, and scotch

Contact: facebook.com/ jabutler // burnley219 (a) googlemail.com (Anti-spam)

MinnyMouse
Regular Member


Date Joined Jun 2010
Total Posts : 197
   Posted 8/19/2010 7:56 AM (GMT -7)   
Thanks everyone for your input. Got some more specific results today and am quite sure my doctor is not going to be very happy when I see him. I am expecting a little more blood work to come. I was diagnosed with Lupus years ago and when I started going to this doctor he said that he didn't believe it was Lupus, then the blood work and symptoms started changing, did more work ups. Two months ago, he said thaI was right on the border and he wanted to wait to treat because I was already beginning a new regemine of drugs. I expect that he will begin treatment. My ANA with specifics came back this morning and overall I went from an 80 to 160 in to months. It's progressed up.
 
It just gets so confusing for me because so many of these diseases, syndroms and conditions overlap. Some autoimmune, some not but all hard for me to figure out what / how they seperate all of it. Myofacial pain, Fibro, Lupus....tender points... trigger points.....LOL and it goes on and on.
 
I will be a pro someday but not now.
 
Thanks again for your help.
Steph tongue
Savella, Lyrica,Mobic,Tramadol,Flexeril,Omeprezole,Vitamin D3,

crazykitty
Veteran Member


Date Joined Jul 2009
Total Posts : 4796
   Posted 8/19/2010 8:29 AM (GMT -7)   
Steph, ANA results can wax and wane. I have always tested negative for ANA but
test postive to the antibody RNP. A positive ANA by itself is no proof of a autoimmune
disease. Yes it is very complicated and can take a very long time to sort it all out.

I was first diagnosed with "borderline lupus. The diagnosis then changed to UCTD
undifferentiated connective disease...meaning we know you have an autoimmune
connective disease, we just don't know which one. With lots of bloodwork, clinical
symptoms a skin biopsy...I was given the diagnosis of MCTD...mixed connective
tissue disease, an overlap of lupus, scleroderma and RA. A trigger point exam and
all over overwhelming body pain, upper and lower on both sides of my body and
overwhelming fatigue confirmed I also had fibromyalgia. I also have a few other
dx's thrown in there.

I hear you, when you say you will be a pro someday. Being proactive in my care,
I have learned alot about my health issues.

Good luck to you and remember whatever your diagnosis is...you will learn to live
with it and still have a wonderful life!

Hugs, Robin
Fibromyalgia, MCTD (Lupus, Scleroderma & RA) Raynaud's, Osteoporosis,
Osteoarthritis, Degenerative Disc Disease, Migraines, and Hypertension
Prescription Meds: Savella, Cyclobenzaprine, Methotrexate, Diltiazem, Boniva,
Folic Acid.  OTC Meds: Multi-vitamin. Vit, D, Vitamin B12 & calciim supplements
 
 
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