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bearhug
New Member


Date Joined Apr 2009
Total Posts : 12
   Posted 5/30/2009 11:04 AM (GMT -6)   
idea   Can anyone tell me the difference between 1 a and 1 b? Is there any significance in response to meds? rolleyes
"bearhug"


hep93
Elite Member


Date Joined Jul 2005
Total Posts : 12014
   Posted 5/30/2009 2:12 PM (GMT -6)   

The info in Dr. Melissa Palmer's book, Hepatitis & Liver Disease, states that Type 1 can be more difficult to treat, and specifically patients with 1b "were less likely to have a long-lasting response to treatment."  Also, "people with genotype 1b have a disproportionately more severe and aggressive course of disease."  People with "1b have been shown to develop cirrhosis and liver cancer more quickly and in a greater percentage of cases than other genotypes."  But she also states, "other studies have concluded that there is insufficient proof of a relationship between genotype and the outcome of the disease."

So it would seem that 1b doesn't respond as well to treatment as 1a.  However, I've been told that type 1 is the most difficult to treat, in general, but that most of the cases in the USA are type 1.

Hope this helps a little.


hep93
Forum moderator - Hepatitis
 
"But that was yesterday, and I was a different person then."
Lewis Carroll, Alice in Wonderland


bearhug
New Member


Date Joined Apr 2009
Total Posts : 12
   Posted 5/30/2009 6:20 PM (GMT -6)   
Thanks for the info Hep93.
"bearhug"

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