Mwl, welcome to the forum. I'm not quite sure what you are asking. What is AoCLF? Some type of chronic liver failure, I'm assuming. Do you mean how do you differentiate between the two? Could you give a little more info/background.
Jalan R, Williams R.
Institute of Hepatology, University College, London Medical School and UCL Hospitals, London, UK. email@example.com
The vast majority of patients that are referred to a specialist hepatological centre suffer from acute deterioration of their chronic liver disease. Yet, this entity of acute-on-chronic liver failure remains poorly defined. With the emergence of newer liver support strategies, it has become necessary to define this entity, its pathophysiology and the short- and long-term prognosis. This review focusses upon how a precipitant such as an episode of gastrointestinal bleeding or sepsis may start a cascade of events that culminate in end-organ dysfunction and liver failure. We briefly review the pathophysiological basis of the therapeutic modalities that are available. Our current strategy for the management of liver failure involves supportive therapy for the end-organs with the hope that liver function would recover if sufficient time for such a recovery is allowed. Because liver failure, whether of the acute or acute-on-chronic variety, is potentially reversible, the stage is set for the application of newer liver-support strategies to enhance the recovery process. Copyright 2002 S. Karger AG, Basel
This is what I found online. I guess it's a new description to differentiate how someone has gotten to ESLD?
To the original poster, I guess the first would be someone whose liver has been deteriorating over time until they got to ESLD, and the second would be someone who was okay but then had an acute event which precipitated rapid deterioration to ESLD.