sirtex treatment

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minnie1964
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Date Joined Dec 2009
Total Posts : 4
   Posted 2/17/2010 11:45 PM (GMT -7)   
Has anyone haerda of or had this? My mom has Hep C & cirrhosis from it. Last year they found a tumor. She has had 2 chemoembolizations. After the 2nd one, they were recommending a transplant, saying her condition was improved enough to do one. After she had a CAT scan last Mon., they determined that the tumor she had is growing again & is blocking her portal vein, & now the transplant is out of the question.They ahve suggested this Sirtex treatment.
I am at a loss for thoughts & words at this point. Any & all support, suggestions, & answers will be greatly appreciated.
Thank you & God bless.

texasdoc
New Member


Date Joined Feb 2010
Total Posts : 1
   Posted 2/18/2010 7:32 AM (GMT -7)   
Absolutely.  It works.  The key though is finding the right Interventional Radiologist to perform the procedure.  The tumor gets an enormous amount of radiation to kill it while the normal liver gets a minimal dose.  It has been shown that the tumor in the portal vein will regress when this therapy is utilized.  Where in the country are you?

minnie1964
New Member


Date Joined Dec 2009
Total Posts : 4
   Posted 2/18/2010 8:24 AM (GMT -7)   
My mom is in Florida. I am in Pennsylvania. She was assessed at Shands in Gainesville FL for the transplant...

hep93
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Date Joined Jul 2005
Total Posts : 12014
   Posted 2/18/2010 10:59 AM (GMT -7)   
Minnie and Texas Doc, just wanted to welcome you both to the forum.  I had not heard of Sirtex, so the info is appreciated.  I had hepatocellular carcinoma (an 11.5 x 12 cm tumor) that had metastasized into the inferior vena cava.  I had chemoembolization and TheraSphere to shrink it at Mayo Jacksonville (FL), and then had a right hepatectomy.  I have been in remission for nearly 4 yrs.  The description sounds like the Sirtex is similar to the TheraSphere, but less damaging to surrounding tissue.
 
ETA:  I wanted to second that having an excellent Interventional Radiologist is extremely important.  I have a fantastic one at Mayo.  He's so skilled that he causes me no pain whatsoever.  He also knows just what to expect from treatment and what to look for.  I still use him when an IV is needed for contrast for a scan, as it has to be done with imagining.



hep93
Forum moderator - Hepatitis
 
"But that was yesterday, and I was a different person then."
Lewis Carroll, Alice in Wonderland

Post Edited (hep93) : 4/15/2010 12:36:22 PM (GMT-6)


minnie1964
New Member


Date Joined Dec 2009
Total Posts : 4
   Posted 4/15/2010 11:05 AM (GMT -7)   
It turns out that my mom could not have the Sirtex treatment after all. They said the blood flow is all shunting over to the non-affected side of her liver, & that the treatment would pour over there instead of going to therRight side where the tumor was located. As per her scan the way it read to me, it looks like that 3cm tumor is gone. but there re still cancerous cells present, to the tune of her count was 911 & now it is over 1200 :( They are recommending chemo-ablation now. Any one have info on that treatment? They also told me that since cancer cells did invade her portal vein, she wil never be a candidate for a transplant. I wonder if that also means she will never be able to have a resection? I think she cannot because she also has the Hep C & cirrhosis...thanks for the info & support.

hep93
Elite Member


Date Joined Jul 2005
Total Posts : 12014
   Posted 4/15/2010 11:42 AM (GMT -7)   

Minnie, I'm sorry your mom wasn't able to have the Sirtex treatment.  Are you sure you don't mean cryoablation?  It is a freezing technique that targets the cancerous tissue.  This sounds like a good option for her.  Transplant and resection are two very different things, so you would need to ask her doctor about that.

Hugs,

Connie


hep93
Forum moderator - Hepatitis
 
"But that was yesterday, and I was a different person then."
Lewis Carroll, Alice in Wonderland


minnie1964
New Member


Date Joined Dec 2009
Total Posts : 4
   Posted 4/15/2010 11:59 AM (GMT -7)   
Thanks Connie. Ah yes, I do know transplant & resection are 2 totally different things. I just have the impression through all of what has been said that her condition of Hep C & Cirrhosis rule out alot of options for her treatment, & the fact that her portal vein has involvement rules out things as well.We have all researched this newest teatment suggestion, & there is no "cry-o" about it. ( I was trying to inject a lil humor there). I even had asked if she was negative for any canceropus cells couldn';t she get the bda liver taken out then, but I was assured that could not happen. On top of it all, she is a bleeder---anotyher reason for them not to do resection. I am frustrated, but hopeful the IP6 treatment I have her on willl work wonders. I will share her progress.:)

hep93
Elite Member


Date Joined Jul 2005
Total Posts : 12014
   Posted 4/15/2010 12:16 PM (GMT -7)   

Chemoablation is self-explanatory.  They would target the cancer cells with some type of chemo.  This is what they did when they gave me TheraSphere (microscopic radioactive beads.) 

I Googled IP6.  I guess you have nothing to lose at this point.

Hugs,

Connie



hep93
Forum moderator - Hepatitis
 
"But that was yesterday, and I was a different person then."
Lewis Carroll, Alice in Wonderland

Post Edited (hep93) : 4/15/2010 1:20:43 PM (GMT-6)

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