Cirrhosis with good LFT?

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New Member

Date Joined Mar 2010
Total Posts : 3
   Posted 3/18/2010 8:04 AM (GMT -6)   
Can one have fibrotic liver in spite of always having had satisfactory liver function tests? The gastroenterologist I have seen said I don't have liver disease, but I have a lot of edema. The flank next to the liver aches. There is a bulge in the right lower abdomen that is considerably more swollen then the left. Also I had pitting edema of the legs that is improved with spironolactone. I've been sick for ten years and now worse. Low potassium and muscle aches are one of the symptoms doctors overlooked.

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Date Joined Apr 2007
Total Posts : 835
   Posted 3/18/2010 11:09 AM (GMT -6)   


Have you had a liver biopsy or are you just wondering if it's your liver that you're having trouble with?  I'm not sure what the bulge on your lower right side would be.  The only thing down there is the appendix unless you have an intestinal issue.

Muscle aches could be because of low potassium.  Probably overlooked regularly as I would guess it's hard to quantify a muscle ache.

Diagnosed with AIH January 2007,
CMV (cytomegalovirus) June 2008
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meds: Azathioprine 100mg, Ursodiol 250mg BID

New Member

Date Joined Mar 2010
Total Posts : 3
   Posted 3/18/2010 7:04 PM (GMT -6)   
I have not had a liver biopsy and I read no one would do that test without high liver enzyme tests. Yes, low potassium will cause muscle cramps and I have low potassium. The connection of low potassium to liver is portal hypertension can disrupt circulation to the kidney. That will cause potassium excretion and sodium excess along with water retention. This can also cause hypertension. I have bloating, excessive thirst, excessive urination and bowel symptoms (light color - was fatty last year. The bowel symptoms are improved from a year ago. I have had itching and other symptoms of liver issues. I have a new onset of right flank pain

Through the years, the liver function tests have been satisfactory. The only one that was high was decades ago and related to diabetes and returned to normal once diabetes was managed. The gastro says no liver disease because the LFT comes back normal.

Episodically, I have consumed alcohol in excess. But I don't have five years of daily drinking in my past if you add them all up. There are year long periods of abstinence in between. The liver tests really don't look different either way.

Elite Member

Date Joined Jul 2005
Total Posts : 12014
   Posted 3/18/2010 8:30 PM (GMT -6)   

John, my advice to you would be to see a hepatologist (liver specialist.)  A GI is okay up to a point, but you really need to pursue your symptomology with a hepatologist.


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"But that was yesterday, and I was a different person then."
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