Confusing hepb test results

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capt73
New Member


Date Joined Jan 2006
Total Posts : 6
   Posted 1/19/2006 6:16 AM (GMT -7)   
Hi there!

New to the board and I am going through issues regarding hep b. This all started in 95 during a routine Dr appointment. Elevated liver results led to a hep B test which led to these two test results.

first test 95

HepB Surface Ab negative
HepB Core Ab reactive

After that I was told that I had been infected and cleared Hep B

second test in 96

HepB Surface Ab negative
HepB Surface Ag negative

After that again I was told that I was not infectuous and had cleared the infection.
I moved on with my life thinking hey I had it but it is gone

Fast forward to 2004.

My new doctor wants to test me again.

HepB surface antigen negative
HepB core Igm antibody negative

This doctor told me that I never had the disease that the original core test was a false positive.

Fast forward to 2006 when my wife and I are going through some infertility issues.

HepB surface Ab negative
HepB Core (total) Ab reactive
HepB Core Igm Ab negative

Now this third doctor is telling me that I could be a chronic carrier! I have had the blood tests repeated and will see a GI hep specialist.

All my research seems to point to a false postive.  I ahve also heard about "occult" hepatitis infections.  I am also in the process of working with a GI specialist and will request an HBV-DNA test, HbeAg and anti-HBe test and a liver function test.

Can anyone shed any light on these tests?

Thanks so much.

lerie
Veteran Member


Date Joined Nov 2005
Total Posts : 966
   Posted 1/19/2006 10:25 AM (GMT -7)   
Hi capt. I don't know about hep b but I just want to welcome you to the forum. There are a lot of knowledgable people here, so hang in there my friend & I'm sure you will get some answers soon.You are on my prayer list, God Bless. later....
lerie


capt73
New Member


Date Joined Jan 2006
Total Posts : 6
   Posted 1/19/2006 3:10 PM (GMT -7)   
Well I just got off the phone with my dr's office and the nurse practitioner I have been working with reported to me that my most recent tests mirrored the fertitlity tests (which were)
 
HepB surface Ab negative
HepB Core (total) Ab reactive
HepB Core Igm Ab negative
 
The nurse practitioners opinions is that I am chronic.  How can this be given my test results which point towards a false positive.
 
I am now referred to a specialist to have viral load/DNA testing. 

lerie
Veteran Member


Date Joined Nov 2005
Total Posts : 966
   Posted 1/19/2006 6:27 PM (GMT -7)   
Hi capt,I don't understand this either, Have you come right out & asked them about all this? I would suggest asking them for a full explaination? Have they done any other liver tests?Let me know what happens. I'll continue to pray for you & your wife. God Bless.later....
lerie


capt73
New Member


Date Joined Jan 2006
Total Posts : 6
   Posted 1/20/2006 5:32 AM (GMT -7)   
Lerie
 
Without the viral/DNA profile and antigen tests I will not know what is going on.  I have consulted with a dr who is a college friend of mine and he thinks this nurse prac is jumping the gun.  He also thinks that if I have been chronic since 95 that I would have symptoms or infected someone else.  All my research online points to a false positive.  I have been referred to a specialist and will be getting to the bottom of this.  Thanks for the prayers and the kind words.  I will pray for you as well.
 
God bless.

Capsid
Regular Member


Date Joined May 2004
Total Posts : 300
   Posted 1/20/2006 6:24 AM (GMT -7)   
The diagnosis can be difficult but to be sure you should have the DNA and antigen tests.

These are markers of the chronic carrier states.

Immune tolerant:

HBeAg: 2000-10,000 U/mL
HBeAb negative
HBsAg 30-150 mg/mL
HBV DNA high
ALT normal
HBc Ab positive
Occurence 10%

HBe+

HBeAg: less than 2000 U/mL
HBeAb negative
HBsAg less than 30 mg/mL
HBV DNA medium
ALT elevated
HBc Ab positive
Occurence 30%

HBe-

HBeAg: negative
HBeAb negative
HBsAg less than 30 mg/mL
HBV DNA medium
ALT elevated
HBc Ab positive
Occurence 20%

Asymptomatic

HBeAg: negative
HBeAb negative
HBsAg less than 30 mg/mL
HBV DNA low
ALT normal
HBc Ab positive
Occurence 40%


Mark


lerie
Veteran Member


Date Joined Nov 2005
Total Posts : 966
   Posted 1/20/2006 10:39 AM (GMT -7)   
Hi Capt, let me know the final outcome when you get to the bottom of it all (soon I hope) I'll continue to pray it all goes well. God Bless & take care. later....
lerie


capt73
New Member


Date Joined Jan 2006
Total Posts : 6
   Posted 1/20/2006 1:18 PM (GMT -7)   
Lerie

Thanks again for the prayers!

I have an appt on Feb 7 to meet with a liver specialist.

lerie
Veteran Member


Date Joined Nov 2005
Total Posts : 966
   Posted 1/20/2006 5:31 PM (GMT -7)   
Hi Capt, I'll be looking for you after you apt. with the hepatologist.God Bless.later....
lerie


capt73
New Member


Date Joined Jan 2006
Total Posts : 6
   Posted 2/8/2006 6:41 AM (GMT -7)   
OK
 
I am back from my meeting with the live specialist.  I looked at my confusing serologies and said 1)  either you had it and it passed or 2) it is a false positive.  He stated though there is no true way to know if you had it.  Even given the positive core result.  The Doctor said I am  NOT chronic and not infectuous based upon the results of my most recent test results. He said there is no reason to repeat any of these tests and even went as far as to tell me  no further blood work was needed.  But for my peace of mind he ordered a hepb DNA test which will be back to me in five days.  He even said this test should come back negative but if it doesnt almost surely it would be a false positive
 
Thanks for all the positive thoughts and prayers.
 
I will continue to pray for you all!
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