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Puresteel
New Member


Date Joined Apr 2007
Total Posts : 4
   Posted 4/7/2007 7:45 PM (GMT -7)   
I just got my biopsy results and one of the comments refers to an "iron stain". Does anyone know what this means?
Thanks

hep93
Elite Member


Date Joined Jul 2005
Total Posts : 12014
   Posted 4/7/2007 9:16 PM (GMT -7)   
Welcome to the forum, Puresteel.

Could you give us the context in which that phrase was used?

Connie

SnowyLynne
Veteran Member


Date Joined Apr 2004
Total Posts : 1539
   Posted 4/8/2007 4:16 AM (GMT -7)   
I had Iron injections years ago,one every day for a week.The stains stayed on my buttocks for a long time.
SnowyLynne


Puresteel
New Member


Date Joined Apr 2007
Total Posts : 4
   Posted 4/11/2007 12:05 PM (GMT -7)   

Here's the total biopsy report:

H&E sections show a core of liver tissue. Within the portal triads, a chronis inflammatory infiltrate is present. The infiltrate is comprised predominantly of small lymphocytes and scattered plasma cells. Focally, the infiltrate does extend beyond the limiting plate and into the surrounding hepatocytes. Within the lobule, focal chronic inflammation is present. Portal arteries, veins and bile ducts appear unremarkable. Central veins also appear unremarkable. A trichrome stain highlights fibrous expansion of the portal triads and focal extension of the fibrosis into the lobule. No bridging fibrosis is identified. An IRON STAIN highlights focal iron deposition, predominantly in Kupffer cells.

By the way: CURRENTLY AST = 61, AST= 80, T3 Uptake = 20 (should be 24+) All other blood is within normal ranges
 
Viral Load = 1,060,000
 
I was originally diagnosed in 96. Had biopsy and everything was normal.
 
Had normal results at annual physical from 97-03.
 
In O4 enzymes were high again AST=74, alt=105, Viral Load 4.5 mil.
 
Frankly, after the news in 04 I went into denial, started drinking more than ever and when the current analysis was done, I was drinkly quite heavily. The only difference was that I began taking a supplement called Juice Plus. Don't know if that had any affect on the reduction in counts or not.
I have quite drinking completely and have just had my blood tests ordered again. Should have the results in a few days.
 
My new DR. (whom I think is a numbskull) wants me to go on the interfuron/ribavarin immediately. He says that he always recommends that after the 2nd biopsy.
 
I plan on attempting to treat it herbally, eliminate the alcohol and employ a suppotive diet and check it again in about 6 months. The combo therapy scares me to death.
 
Any thoughts on the bove would be most appreciated.
 
 


hep93
Elite Member


Date Joined Jul 2005
Total Posts : 12014
   Posted 4/11/2007 11:55 PM (GMT -7)   
Puresteel, the stains are just mediums added to different parts of the biopsied material, to bring forth ("highlight") conditions they want to look at more closely. You look like you would be a good candidate for treatment. Why does it scare you?

Milk thistle, distilled water, no soda (and absolutely no alcohol), are some of the things I know that people have tried. It probably would do you no harm, but I'm not sure if it would do any good, either. Stopping drinking--even wine or beer--is the #1 best thing you can do for your liver.

Connie

Puresteel
New Member


Date Joined Apr 2007
Total Posts : 4
   Posted 4/12/2007 8:04 AM (GMT -7)   

hep 93,

thank you so much for the reply.

The reason that treatment scares me is from what I have read on this and other forums. That the treatment is worse than the disease itself. Some of the stories are downright horrific.

Furthermore, if I did go on the treatment, I would most likley have to go on disability, at least for a while and there are alot of people that depend on both at work and at home.

Since quitting drinking and changing my diet, I feel a little better each day and today I feel great. Not to say that the disease will not progress and the symptoms return and treatment become inevitable. So on that note, let me ask you, have you been on the treatment and what was your experience? Why should it not scare me?

Thanks again!

Oh, by the way, I expect that I have had this for probably over 30 years. I was in a hepatitis ward in Tripler Army Medical Center in 1972. I didn't have hepatitis, I had a VERY bad case of erythyma multiforme (Huge open sores all over my body) They think I got it from wandering around in the swamps, but not sure. Anyway, the conditions of the ward were anything but sterile and tranference was most definately a possibility.


Post Edited (Puresteel) : 4/12/2007 9:06:35 AM (GMT-6)


hep93
Elite Member


Date Joined Jul 2005
Total Posts : 12014
   Posted 4/12/2007 5:23 PM (GMT -7)   
Well, that was really intelligent of them to place you in a hepatitis ward, wasn't it? Geez!

I was diagnosed with chronic active hep C in '93 per biopsy. In late '92, a blood test for C was positive, but there was no way to know if it was just chronic or chronic active except through biopsy. (I know I contracted it in the late 60s.) I did try treatment, which at the time was only interferon. It decreased my white cell count so drastically that my hepatologist took me off treatment (after first cutting the dose in half, which had no positive effect.) I tried it again about a month or so later, and the same thing happened. The first time, I took it for 6 wks. and the 2nd time only 4 weeks. What happened as a result of no treatment was that I developed, in time, a large, cancerous tumor in my liver. I had 2 types of treatment which managed to shrink the tumor significantly, and killed most of the cancer cells. However, some do remain. Therefore, I am set to undergo surgery on the 30th to remove the entire right lobe of my liver. Once recovered from that, I will have to go on treatment or the same thing could likely happen again.

When they came out with the combo, I was also afraid to take it as I heard one had to take it for a year and that the side effects were really bad...making it impossible for most to continue working. So I understand about that. I know of a few people who have applied for SSI and have been successful in getting it (it's like a temporary disability, through Social Security and your state.) I have been on permanent disability since 2005, so I don't have to worry about going to work now.

I can tell you that hep C (or any liver disease) makes one extremely fatigued for no good reason. Sleep doesn't matter. I can (and do) sleep 14-16 hours at a time and still feel like I'm walking through molasses when I get up. So if you do not take the treatment, you can develop cirrhosis, end-stage liver disease, or cancer as I did. There really is no room for fear of something that can give you a longer life.

Connie

Puresteel
New Member


Date Joined Apr 2007
Total Posts : 4
   Posted 4/12/2007 5:57 PM (GMT -7)   

Connie,

Thank you so much for the reply, your time and your obvious compassion. I have had a short stint, couple of months, of fatigue but seem to be coming out of it now. I have had many other stints in the past or maybe they were hangovers, or both. Now, I can sleep about 6 hours and wake up refreshed. As far as stamina, I can out work most people both in the office and on the farm. I am an engineer and was the Vice President of my company. The fatigue and stress got so bad that I had to leave the big city (Miami) for home, in the country of NC. When I gave up my vice presidency the comapny decided to set me up in my home to do designs as my health allowed. So I am unbelievably blessed in that regard. I am feeling good now and can work a full day in the office and until dark on the farm. Hard work has been my life and I sure hope that I don't have to give it up. The change to the country has helped and giving up the drinking has helped even more.

The counts are low now, I feel well and the one thing that I didn't say about the biopsy was that the final diagnosis was that the HepC activity was "minimal". I am 51 now. I just pray that the good Lord will allow me another 15 or 20 years of health so I can maintain my work on the farm. After that I will consider I've had a good life and the HepC can go to hell while I go the other direction. Then I will be rid of it! OR maybe they will develop a real cure that isn't so dramatic.

Thanks again for your thoughtful insight and attention. I feel bad for taking up your time for it appears that there are others on the board that are much worse than I, or maybe that's where I'm heading. Lord only knows. I am committed to praying his blessings on all battling with this demon.

God Bless,

Mike (Puresteel)

 

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