I started on Align back in April, along with Simax, and Protonics. After crying at the end of each month for the $100 pill bill, so after two months of it, and no changes I elected to drop the Align.
Personally I saw nothing from it, could be the mix of the other stuff I was taking. I have IBS-C for the most part, with some D here and there.
I am about to get off the Simax as well, the side affects are killing. The doc wanted a two month trial, and its been a rough two months, so hopefully she will have something else for me today when I see her.