Hi tug, welcome to the forum. It depends on how much weight you are talking about here, but weight loss is a "red flag" symptom and should be worked up by your physician. Have you had a colonoscopy?
Co-moderator - IBS Forum
Please always remember to consult your medical professional regarding your medical questions; this forum is intended to provide patient-to-patient support. Although some of us have healthcare backgrounds, we cannot diagnose or treat patients on the board.