I went and seen my gastro doctor on Monday and he is considering putting me on Lotronex. Nothing that I have tried yet has been working. The only thing that helps is immodium but only for a few days at a time then I have to give my body a break for a few days and start over again. Has anyone ever taken Lotronex? If so did it help at all? I am having a laprascopy done next Wednesday to look for endo and check a few other things like fibroid tumors. If things are bad I will have a hysterectomy. I was hoping maybe my female problems were causeing my urgent bowel movements but I won't know that until after surgery and even then only if my issues get fixed.