When I first tried it, I read somewhere here - possibly on the UC forum - that you should take it on a completely empty stomach. Since I am used to eating a light breakfast as soon as I wake up I didn't think morning was best. And since I also try not to eat solids after dinner (a trick I've determined manages my IBS symptoms better), by 10 or 11 pm, my stomach is empty.
Now if you don't eat breakfast, try it in the morning.
But bedtime seems to be best for me.
Sometimes if I am really off track and having trouble, I take a second dose mid-morning, 2 to 3 hours after I've eaten breakfast.
For some reason it works very well if your stomach isn't full, you don't want the pill to dissolve with food or in the stomach. It should remain encoated and in tact until it reaches the lower colon (where you need it most).
Good luck! I started with the 50 but have moved up to the 80. Pricier but it seems to work well for me.
- Rectal CA 4/29/99, Stage I, 90% sigmoid/15" of colon/GB removed, temporary colostomy, reversed 6-26-99
- Chronic IBS/D symptoms, multiple bm's, on low residue diet
- Colace 50 mg, twice daily + Probiotic: Renew Life/Ultimate Flora/Critical Care/80 Billion daily