I have had IBS for over 20 years now. Had taken a powder OTS Fiber... then when discontinued dr. wrote out prescription for generic miralax making it much cheaper. I need to take this on a nightly basis so i would go ever morning and I swore by it. Because of change in ins. companies, the drug is no longer covered and now am looking for something new. just start Amitiza 48 and giving me bad abdominal cramps and am not going to the bathroom every morning like used to. Don't work so taking OTC drugs is too expensive for me for Benefiber and Metamucil don't work. Any suggestions? I too have depressions, back problems, leg problems, am 48 years with a 5 year old starting kindergarten on Tuesday 9/7/10. Help is greatly appreciately. Powder form is no problem for me.