does lab make a difference?.......

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KaAl
Regular Member


Date Joined Sep 2007
Total Posts : 151
   Posted 12/23/2007 8:04 PM (GMT -7)   
Hi. Just wondering what lab is better for Lupus testing, Lab Corp or Quest? Or are they both compatable?
 
Thanks

AlwaysRosie
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Date Joined Jan 2005
Total Posts : 8616
   Posted 12/23/2007 8:34 PM (GMT -7)   
Hi KaAl,

Great question KaAl . . . I have wondered if there is a difference between labs. I wonder if there is any rating system on major labs. I have actually preferred the lab work done at our local hospital. . . but I have to pay 20% of the bill. If I use Lab One (Quest), it is totally paid for.

Maybe some of the others have some knowledge about this.

Blessings!

In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Hashimotos, Inflammatory Bowel, Inflammatory Arthritis

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okie
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Date Joined Dec 2006
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   Posted 12/23/2007 8:56 PM (GMT -7)   
I don't know the answer either but I have compared different labs my different doctors have used and I noticed that the normal range is not always the same. On some lab tests that said I was normal I would have been considered high or low if it had been done at the other lab. I'm not sure why that is though.
carol
God Bless
Lupus like symptoms, with pbc symptoms, stage 4 COPD w/CHF,  Cancer survivor.  Osteoporosis,osteoarthritis
Prednisone,Plaquanil800mg,vicodin 4x5mg,Evista60mg, Effexor 150mg, HCTZ25/Triamterene37.5mg,Xanax x3 
Only two defining forces have ever offered to die for you: 1. Jesus Christ 2. The American G. I
 
 
 


Bsime
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   Posted 12/25/2007 9:59 PM (GMT -7)   
Carol,
 
Their is sometimes a wide variance on ranges.  A good doctor will not only look at a specific value but at all the others as well.  We all have slightly different chemistry and what is normal for one is not for another.  I have a myostis disease and one of the primary test is for CPK which measures muscle breakdown.  Different labs are all over the place in values but in truth trends up and down are more important than the absolute value.
 
As medical researchers get better data these values are often adjusted to reflect the new information anyway.
 
Bill
Mixed connective tissue disease (systemic lupus, scleroderma, polymyositis), Raynauds phenomena, Hypertension, Barrett's esophagus.
 
Meds: prednisone 5mg, 50mg imuran, Lotrel 40/5mg, maxide 37.5/25mg, folic acid, potassium, aciphex 20mg, multi vitamins.
 
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Butterflake
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Date Joined Jun 2006
Total Posts : 1551
   Posted 12/26/2007 12:20 PM (GMT -7)   
Hi Everyone.  I have a BS in medical technology (lab), so I have your answer.  As each laboratory buys any "machine" to run tests, the lab is required to run numerous random samples thru the machine, calculate the "average" and establish a range for that machine, in their lab, using their patient's blood. Therefore, each lab has a different set of normal values (an expected range) even if they are using the same brand of machine as a lab across town. 

Dx: SLE diagnosed 2005, major depressive disorder, diabetes, fibromyalgia, gerd, sleep apnea (use a CPAP), hypertension, IBS
Tx: plaquenil, methotrexate, Imuran, prednisone, prozac, celebrex, lisinopril, actos, lipitor, nexeum, seroquel, arthritis tylenol  PRN: ambien, neurontin, promethazine, xanax
supplements: multi vitamin, C, flaxseed oil, calcium/D
             Better living through chemistry :D    Donna
 


redrose77
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Date Joined Sep 2005
Total Posts : 2573
   Posted 12/26/2007 1:16 PM (GMT -7)   
I have no clue on labs. I do know results will vary by lab and lab tech.
Dx:fibromyalgia 2002, systematic lupus 2005, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, pregnant due May 2008
Tx: plaquenil, Enbrel, Darvocet, Singulair, Flexeril, Baby Asprin,Prednisone


AlwaysRosie
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Date Joined Jan 2005
Total Posts : 8616
   Posted 12/26/2007 5:46 PM (GMT -7)   
Thank you butterflake . . . that makes very good sense!! It sounds like it might be similar to a bathroom scale. Mine may very slightly from yours, but if you step on the same scale every day at the same time, you will see the gain or loss correctly. It sounds like it might be a good idea to be using the same lab repeatedly when possible.

Thanks!!

Blessings!

In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Hashimotos, Inflammatory Bowel, Inflammatory Arthritis

Clickable Links:  Lupus Resources    Lupous.Org   Lupus Criteria (4 of 11)   Lupus Chapter Locator


Ginny
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Date Joined Feb 2003
Total Posts : 5514
   Posted 12/26/2007 9:23 PM (GMT -7)   
Yes, Butterflake is absolutely right.  For my blood coagulation tests (PT, INR), I have to go to the same lab every week because each lab will have a slightly different calibrated machine.  The lab I go to vs the lab at one of the hospitals, for example, can be off by 30%. My INR can be 2.8 at one lab, and the same sample tested at another will be 3.4.  BIG difference.  So if I use a different lab every week, I'm not getting consistant results.  Stick with one lab and just go to it for everything.
 
This is a great thread.  Good for asking the question KaAl!
 
Ginny
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

33 years old. Diagnosed with lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, seizure disorder-(miraclulously disappeared!), Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, monopril, calcium, Cykolokapron, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus


KaAl
Regular Member


Date Joined Sep 2007
Total Posts : 151
   Posted 12/28/2007 9:14 PM (GMT -7)   
This did turn out to be an informative thread. Ok, got an extention to this thread........what about the best time to get your blood drawn, does it matter? For example, is it better to get it drawn on a monday verses a thursday when the wk end is right around the corner? Will the blood "sit" too long?
I wonder if this makes a difference?!!!

KaAl

mom46
Veteran Member


Date Joined Dec 2004
Total Posts : 8198
   Posted 12/28/2007 10:15 PM (GMT -7)   

The doctors I work for use lab Corp and the local hospital. It depends on the type of tests ordered.

  I think depending on the blood tests orderd would play a factor in when to get them done. Some blood tests take alot longer to get the results than others. I think its better to get blood work done on a monday and they should all be back by the next monday. Thats just my opinion. Take care.

                                                               Babs


 
Dx: Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Neuropathy,CAD
Meds:arava,prednisone,plavix,aspirin,protonix,,zanaflex,xanax,
mirapex,advair,foxamax,Vytorin,folicacid,lunesta,Tramadol
 
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AlwaysRosie
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Date Joined Jan 2005
Total Posts : 8616
   Posted 12/29/2007 2:39 AM (GMT -7)   
KaAl . . . I have had my lab ask me NOT to do some of my testing on a Friday for that very reason. They also ask me to come early in the day for some of my tests. It depends if your lab is "sending out" your blood to be tested. The hospitals usually do it "in house" so it really shouldn't matter when you have it drawn there.

I would call YOUR lab with YOUR labe requests and ask. Some labs need to be done after fasting and some don't matter. I usually go straight to the lab after my doctor appointment and ask them about best time etc. Usually they can do it right away.

Blessings!

In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Hashimotos, Inflammatory Bowel, Inflammatory Arthritis

Clickable Links:  Lupus Resources    Lupous.Org   Lupus Criteria (4 of 11)   Lupus Chapter Locator


MizPiggy31
Regular Member


Date Joined Feb 2012
Total Posts : 111
   Posted 12/30/2013 7:15 PM (GMT -7)   
My Rhuemy prefers Lab Corp. She said the way that they do the ANA testing (florescent) is more accurate than Quest. I can say from my lab work using Lab Corp my ANA has been positive and using Quest it was negative.
Between diagnoses (auto-immune or fibro)
Planqueil 200mg twice a day, Lisiniprol

amyamy
New Member


Date Joined Oct 2013
Total Posts : 3
   Posted 1/4/2014 9:01 AM (GMT -7)   
I have noticed through Quest my ANA has been significantly high 1:1280 on two different occasions, six months apart.

In between that six months it was drawn and tested through Lab Corp and it was completely negative. Then tested again later and it was 1:80.

I can not imagine two labs varying so significantly in their testing.
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