test results....

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Regular Member

Date Joined Sep 2007
Total Posts : 151
   Posted 1/8/2008 4:44 PM (GMT -6)   
Does anybody know what medications cause a false positive ANA? I read that certain medications can cause a false positive ANA but doesn't specify which ones....DO you know if antibiotics can cause a false positive?

Veteran Member

Date Joined Oct 2004
Total Posts : 2244
   Posted 1/8/2008 4:55 PM (GMT -6)   
This is what I found on the Internet:

Factors that can interfere with your test and the accuracy of the results include:
Medications, such as hydralazine (Apresoline), procainamide (Procan, Pronestyl, Promine), and certain anticonvulsants (such as Dilantin, Mysoline). These medications can cause a form of systemic lupus erythematosus (SLE) called drug-induced lupus. Lupus resulting from these medications may cause a high antinuclear antibody (ANA) titer.
Medications, such as antibiotics (isoniazid, penicillin, and tetracycline), birth control pills, lithium, and some diuretics, such as chlorthalidone (Hygroton).
Heart or blood pressure medications, such as acebutolol (Sectral), captopril (Capoten), atenolol (Tenormin), metoprolol (Lopressor), lovastatin (Mevacor), and quinidine.
Aging. Some older adults (5% to 40%) may have mildly elevated levels. Older women appear to have higher ANA titers than older men.
Steroids, which may cause a false-negative result.

Here is the website where I found the info: answers.yahoo.com/question/index?qid=20061004144943AAGc17E

Here is another website that explains the ANA test: www.labtestsonline.org/understanding/analytes/ana/test.html

I hope this helps! Take care

Trust in the Lord with all thine heart, and lean not unto thine own understanding ~ Proverbs 3:5 ~

DX: Hashimoto's 1999, Celiac Disease (AKA: gluten sensitivity) 2003, Raynaud's 2004, Lupus 2005 and Sjogrens 2006
Meds: Imuran, Plaquenil, Flexeril, Piroxicam, Levoxyl, Folic Acid, Lortab (as needed), Magnesium Citrate and magic mouthwash (as needed for mouthsores)

Post Edited (jhmom) : 1/8/2008 3:00:07 PM (GMT-7)

Regular Member

Date Joined Sep 2007
Total Posts : 151
   Posted 1/8/2008 6:50 PM (GMT -6)   
Thanks jhmom, I read that site too, but I was a bit confused.....I asked my rheamy if antibiotics can cause a false positive ANA. She said no, but the site says otherwise.

Anybody know for sure?

Veteran Member

Date Joined Jan 2005
Total Posts : 8616
   Posted 1/8/2008 7:29 PM (GMT -6)   
KaAl . . . I don't remember the blood work . . . but the doctor can tell by certain bloodwork if it is drug induced. Sorry I don't recall where I learned that. Bottom line . . . your doctor would/should pick up on the fact that its drug induced - if it really is. If you ask your doctor, he/she can reassure you either way.


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Regular Member

Date Joined Sep 2007
Total Posts : 151
   Posted 1/8/2008 7:37 PM (GMT -6)   
Thanks Rosie....I went back and re-read the article and it states that certain medications such as antibiotics (isoniazid, penicillin, and tetracycline) can effect your test, doesn't say anything about the antibiotic I was taking (cerfuroxime, which is the cephalosporin class).
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