Question on Methotrexate

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Oct 2007
Total Posts : 100
   Posted 3/6/2008 8:17 PM (GMT -6)   
Wondering what dosage of Methotrexate every one is on.
I'm currently on 15 mg/week.  However my rheumy said if I have a hard time getting off of prednisone, he can up my methotrexate because I'm not yet at the maximum dosage.
SLE: 07/07, Irritable Bowel Syndrome, migraines
400 mg. plaquenil, 9 mg. prednisone, 2400 mg. ibuprofin, 15 mg. methotrexate, folic acid, asacol, caltrate-D, wellbutrin, paxil, lybrel, Keppra (as needed)

Regular Member

Date Joined Jan 2006
Total Posts : 90
   Posted 3/6/2008 9:04 PM (GMT -6)   

I am currently on 10 mg of injectable mtx a week, and the most I could tolerate was 15. It helped me wean off of pred. and I now only use prednisone when I am flaring. I unfortunately cannot tolerate more!

Hope this helps,


Veteran Member

Date Joined Oct 2004
Total Posts : 2244
   Posted 3/6/2008 9:18 PM (GMT -6)   
I am on 7.5 mg, I just started taking it about 3 weeks ago. I am also on 100mg of Imuran. I hope it works well for you so you can come off pred.

Trust in the Lord with all thine heart, and lean not unto thine own understanding ~ Proverbs 3:5 ~

DX: Hashimoto's 1999, Celiac Disease (AKA: gluten sensitivity) 2003, Raynaud's 2004, Lupus 2005 and Sjogrens 2006
RX: Imuran, Plaquenil, Methotrexate, Flexeril, Piroxicam, Levoxyl, Folic Acid, Lortab (as needed), Magnesium Citrate and magic mouthwash (as needed for mouthsores)

Veteran Member

Date Joined Jan 2005
Total Posts : 8616
   Posted 3/7/2008 10:34 AM (GMT -6)   

I started at 15 mg and upped to 20mg. I took mtx for about a year - over a year ago and did quite well on it. The biggest thing I noticed was that the fatigue lifted quite a bit.


In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Hashimotos, Inflammatory Bowel, Inflammatory Arthritis

Clickable Links:  Lupus Resources    Lupous.Org   Lupus Criteria (4 of 11)   Lupus Chapter Locator

Regular Member

Date Joined Oct 2005
Total Posts : 251
   Posted 3/7/2008 11:01 AM (GMT -6)   
I'm at 15mgs too. My liver enzymes have jumped up a couple of times so my Rheumy doesn't want to increase it any further and I'm doing okay at 15mg anyway.
SLE diagnosis 10/05 now changed to RA 3/06, Endometriosis 5/05, PCOS 1990
Meds: Metformin ER 1500mg (PCOS); Loestrin BCPs (Endo); Methotrexate 15mg (RA); Metanx 5mg (RA); Orencia 750mgs (RA); Lunesta 2mg (as needed); Prevacid

New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, October 28, 2016 12:54 PM (GMT -6)
There are a total of 2,713,478 posts in 299,196 threads.
View Active Threads

Who's Online
This forum has 153792 registered members. Please welcome our newest member, Dorianna.
348 Guest(s), 13 Registered Member(s) are currently online.  Details
scifigal2k, blueberrymuffin, Skyy, astroman, PamSmith, Huddie, pmm73, Navigator, Dorianna, LMusings, julymorning, Sissy63, iPoop

Follow on Facebook  Follow on Twitter  Follow on Pinterest

©1996-2016 LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer