Does Lupus physically affect the brain and cause depression?

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Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/17/2008 5:13 PM (GMT -7)   
Researching on the internet I found one scientific paper that indicates the brain is physically affected by Lupus, and can cause depression.  Just wanted to know what all of you think about it. 
 
Hester
Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


Barbara Lee
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   Posted 10/17/2008 6:59 PM (GMT -7)   
Hi Hester:

That sounds like an interesting article. I have to say that lupus doesn't necessarily cause depression. I know lupus can cause problems with cognitive problems, strokes, seizures, and such things. I think being chronically ill can cause a lot of depression.

I've found that many people of the HW site have issues with depression. Having a condition where you hurt all the time and you're always taking a pill or seeing a doctor, takes a huge toll on us. I have to say I've struggled on and off with depression over the years. I can say my depression is about as low as it can be. I'm having feelings like I did when I was a teenager and ready to give up on life. I mean I'm not to thrilled about whats going to be coming for me in the near future. I will continue to fight and hang on.

I hope that if you're suffering from depression that you're able to get either a good therapist or an anti depressant that you can tolerate. You've come to the right place and we're all here for you.

Best Wishes,
Barbara
dx fibro, SLE, glaucoma, cateracts, bells palsy, depression, migraine headaches, gastreopaersis, chronic anemia, RA,MDS (Blood Cancer). Tons of meds.


Ginny
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   Posted 10/17/2008 7:00 PM (GMT -7)   

Hi Hester,

I am an absolute believer that the disease itself can cause changes to the brain resulting in personality changes, depression, anxiety, etc.  For those afflicted with CNS lupus, it can be devastating.

Another condition that seems to go along with lupus, is Fibromyalgia.  It causes an imbalance between the hypothalmus, pituitary gland and the adrenal glands.  Signals get mixed up which ends up causing all the pain and fatigue of Fibro.

There's a lot of information out there on lupus, Fibromyalgia and how it affects the central nervous system.


I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

34 years old. Diagnosed with Lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, Cozaar, Zoloft, calcium, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/18/2008 7:38 AM (GMT -7)   

Hey Ginny and Barbarra Lee,

Two differing opinions, and would probably find this same thing in the scientific community.  I was hoping I guess that it is, and that maybe plaquenil, and prednisone would be able to help with the depression.  but even thinking it now, I realize it makes no sense. 

I too believe that Lupus affects our brain in ways that can result in depression, and mood swings.  But just one scientific paper is not going to find us any relief anytime soon.  And in this paper it talked about prednisone itself causing depression.

I take Doxepin every day Barbara Lee, 50 mg, four times a day.  I take it all at bedtime.  but after 22 years in therapy, I think  I am going to take a break from the therapy.
 
Many thanks to both of you for your response.
 
Hester
 
 
Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


Bsime
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   Posted 10/18/2008 8:13 AM (GMT -7)   
Hester,
 
19 neuropsychiatric syndromes have been identified with SLE.  It has affected me in short term memory, concentration and lessened ability to cope with stress.  The change was very sudden but it has gotten better over the past 3 years.
 
Here is an article summarizing the subject.
 
 
The subject of depression is discussed in the article and here is an excerpt:
 

"Depression and anxiety are common complaints of SLE patients, the etiology of which may be a direct manifestation of CNS involvement or a secondary response to a life-altering chronic illness. Mood and psychological factors are known to influence reports of cognitive functioning as well as performance on neuropsychological tests.[14] The high prevalence of psychological distress in this population has led some to argue that cognitive deficits can be attributed to the psychological factors of living with a chronic disease.[15] However, high self-ratings of depressive symptoms have been found in SLE patients compared with other chronic disease populations. Kozora et al.[16] found increased self-ratings of depression in their sample of SLE patients without neuropsychiatric symptoms compared with rheumatoid arthritis patients and healthy controls. Significant associations were observed between the somatic symptoms of depression and a cognitive domain score for learning based on performance on memory measures; there was no relation between the cognitive aspects of depression and neuropsychological test performance."

Keep in mind that anyone with a serious and chronic illness can be subject to depression even if the disease itself does not cause it.  We all wrestle with our illness and struggle with the idea that it is incurable and life long.  At least I am a senior and have less time to deal with it than young patients....small consolation but that does make me focus on enjoying each and every day I have left.

Bill


Mixed connective tissue disease (systemic lupus, scleroderma, polymyositis), Raynauds phenomena, Hypertension, Barrett's esophagus.
 
Meds: prednisone 5mg, 50mg imuran, Lotrel 40/5mg, maxide 37.5/25mg, folic acid, potassium, aciphex 20mg, multi vitamins.
 
Maintain your optimism and you can beat the odds.
 
"Although the world is full of suffering, it is also full of the overcoming of it."  Helen Keller
 
 


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/18/2008 10:49 AM (GMT -7)   

Hey Bill,

Thank you for your most informative response.  I registered at the sight that you provided.

I was surprised and encouraged by the following excerpt from the article.

Despite the variability in study results, it is now generally well accepted that cognitive dysfunction is a clinically important manifestation of SLE with many etiologic factors contributing to its presentation.
 
Hester
Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


redrose77
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Date Joined Sep 2005
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   Posted 10/18/2008 11:43 AM (GMT -7)   
I know for a fact my mood gets funky when I am flaring- very wild mood swings and definately can't cope with stress. My PTSD gets 200 times worse too. I get really jumpy and freak at the slightest thing that normally would just scare me a little. I just want to cry sometimes from how much this has affected my life and brain.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, now cellcept


Ginny
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Date Joined Feb 2003
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   Posted 10/18/2008 1:41 PM (GMT -7)   
Hi Hester,
 
You got some excellent info from Bill.  He's a smarty wink .  Also, you mentioned prednisone as being a possible trigger for depression.  Abo****ely!  Prednisone, especially in the higher doses, will cause some or most people significant depression or anxiety. I"m one of them.  Cortisol, whether it's natural or synthetic, is the "fight or flight" hormone.  It will automatically cause anxiety if it's in abundance in the blood stream. That anxiety, will most often trigger depression at the same time.  I"m dealing with this right now, as we speak. I'm getting cognitive and drug therapy for it because it's so severe.
 
Ginny
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

34 years old. Diagnosed with Lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, Cozaar, Zoloft, calcium, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus


Barbara Lee
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Date Joined Sep 2003
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   Posted 10/18/2008 7:44 PM (GMT -7)   
Hi Hester:

I see Jinny, Redrose and Bill gave you a lot of good information. We each respond differently to depression, I was going on my previous bouts of depression. I've not had any CNS lupus but I've suffered with depression on and off since I was 17 and tried to kill myself.

I know when I take high doses of prednisone I do become somewhat mental. It's hard on the system and yet it can make us so much better. I've got all the side effects from taking my steroids all the time. I know having a chronic illness causes me a lot of depression and I would love to be able to stop therapy and avoid that doctors office too.

I wish you well and I hope you can cope with all that may or may not affect you. Please, stay in touch and know that I'm praying for you.

Best wishes,
Barbara
dx fibro, SLE, glaucoma, cateracts, bells palsy, depression, migraine headaches, gastreopaersis, chronic anemia, RA,MDS (Blood Cancer). Tons of meds.


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/19/2008 7:21 AM (GMT -7)   

Hey Ginny, Barbara Lee and Redrose,

Ginnny you said that you are getting the cognitive, and drug therapy for it.  What kind of treatment do they give you?

I have cycles of bad days, where anxiety is high, and depression.  the good days, I can think well, and feel normal.  Each cycle lasts about two weeks.

I was encouraged somewhat by those of you who spoke a while back, about experienciing missing time, and doing and saying things that you do not remember saying or doing. I experience these things too.  And just wondered if the cause could be found to be physical, and not just mental.  If Lupus affects the brain, Is it a physical effect that maybe presents itself mentally?

Bill's mental effect got better.  and that is a good sign.

Bill's findings also state that anxiety and depression are common complaints of people with Lupus. 

How do you cope with it?  What do you do during the bad days of high anxiety and depression.  for me it presents itself in cycles.  for about two weeks I am deeply depressed and feel like I have to hold myself together or I will fly apart.  and the other two weeks, I feel normal, and not anxious or depressed.

I have it written down to talk to my rheumy about it, when I see him on the 23rd.  In four more days.  I hate that my appointment is in the middle of these bad days, when I cant think well, and feel such high anxiety levels.

Thanks to all of you for your responses.

Hester


Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


redrose77
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Date Joined Sep 2005
Total Posts : 2573
   Posted 10/19/2008 12:45 PM (GMT -7)   
Hester, what I am going through is a physical affect- the lupus is attacking my central nervous system. It is causing damage that presents itself as cognative and mood issues. Some of the damage can be reversed but some will be forever. So if they get it soon enough the symptoms might be reversable but the longer it goes on the more chance there is for serious damage no one can fix.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, now cellcept


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/20/2008 8:50 AM (GMT -7)   

Hey Redrose,

I am not trying to be picky, just really want to understand what is going on with you.

What kind of cognitive symptoms do you have?  What kinds of mood issue  happens to you?  How did they find out that your cognitive and mood issues were related to Lupus, or caused by lupus?  do you lose the ability to think? to remember?  What kind of mood change do you experience?  Do you recognize it as it is happening, or do you suddenly find yourself, in a mood that is different to you immediately?

I apologize if I am pushing too hard to define your symptoms... It is important to me to understand.  Please tell me if I am asking too many questions.

Thank you for your response

Hester

redrose77 said...
Hester, what I am going through is a physical affect- the lupus is attacking my central nervous system. It is causing damage that presents itself as cognative and mood issues. Some of the damage can be reversed but some will be forever. So if they get it soon enough the symptoms might be reversable but the longer it goes on the more chance there is for serious damage no one can fix.


Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


redrose77
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Date Joined Sep 2005
Total Posts : 2573
   Posted 10/20/2008 11:43 AM (GMT -7)   
I will answer the ones I can, the truth is they are assuming a lot but since lupus treatment fixed the problem in the past why do something as dangerous as a brain biopsy? I have memory issues, wild mood swings, worsening of anxiety issues and flashbacks related to ptsd, my visual and brain disconnected- I could see something but not comprehend what I was seeing, and a bunch of other vague stuff.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, now cellcept


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/21/2008 7:29 AM (GMT -7)   

Thank you Redrose for your response.  I see the rheumy thursday.  I am going to ask him if it is possible that the mental episodes that I have is related to Lupus or Sjogren's.  I am wondering if Lupus caused the problems.  It would not bring me relief of course, but at least I would have an answer, and I have none at the moment.

I don't know that I have wild mood swings, but I certainly have opposite ones.  wake up one morning and depression and axiety are mine for two days, two weeks, or however long.  Wake up some other morning and the depression and anxiety is gone to be replaced with good days and ability to think, feel emotions, and speak well.  This happens repeatedly and has been doing so for several years.

I don't have much hope for the doctor responding to me positively on Thursday.  I don't even know how to proceed if he did want to pursue this avenue of tests.  But I am hoping that he will be open to my question, and be willing to proceed with it.

Thanks again RedRose

Hester

 


Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


Ginny
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Date Joined Feb 2003
Total Posts : 5514
   Posted 10/21/2008 11:01 AM (GMT -7)   
Hi Hester,
 
My anxiety and depression come and go in cycles too.  I get one week of relief, and 3 weeks of hell.  For me, part of the issue are my hormones. I might be in perimenopause.  Something my family doc mentioned last week.  Terrible anxiety and depression symptoms are the #1 "red flag" for perimenopause. I'll be 35 in the new year.  I'm not too young! 
 
My one week of relief is not perfect though. I stil have the anxiety, but the depression is much better.
 
I'm seeing a counsellor in regards to my PTSD. I had a near death health scare in the summer of '07.  Post traumatic stress is something I'm dealing with now because of that.  I've also been put on Zoloft.  An anti-anxiety/depression med.  I start it tonight.  I'm nervous!  I hope it helps.  I need relief.  That's the treatment I'm getting.
 
Do you notice that your bad weeks correspond with your period? I'm not sure how old you are, or if you've already gone through menopause.  But that could be why your symptoms go in cycles.
I can do anything through Jesus Christ who strengthens me. I have learned in whatever state I am in,to be content. Phillipians 4:11-13

34 years old. Diagnosed with Lupus in 2000. Fibromyalgia, anti-phospholipid syndrome(APS)(stroke),Sjogren's, Raynaud's, Libman Sach's Endocarditis, vasculitis, sacroiliitis, arthritis (neck) . Prednisone, Imuran, Coumadin, Clobazam, Amitriptyline, didrocal, Cozaar, Zoloft, calcium, multi-vitamin, vitamin D, Magnesium, vitamin B6, Acidophilus


redrose77
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Date Joined Sep 2005
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   Posted 10/21/2008 11:25 AM (GMT -7)   
Hester, I would suggest a neurologist to test for cns involvement. My rheumy manages my meds but the neurologist has to manage the testing and such.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, now cellcept


Serina
Regular Member


Date Joined Aug 2008
Total Posts : 431
   Posted 10/22/2008 7:02 AM (GMT -7)   
Thank you Ginny for your response.  My periods completely stopped at age 42.  I am 62 now.  I had symptoms before then, just did not know what they were.  And you are right, these mental symptoms I described did start around the same time.  Treatment for the menopause however had no affect on the cycles of depression and anxiety.
ginny said...
Hi Hester,
 
My anxiety and depression come and go in cycles too.  I get one week of relief, and 3 weeks of hell.  For me, part of the issue are my hormones. I might be in perimenopause.  Something my family doc mentioned last week.  Terrible anxiety and depression symptoms are the #1 "red flag" for perimenopause. I'll be 35 in the new year.  I'm not too young! 
 
My one week of relief is not perfect though. I stil have the anxiety, but the depression is much better.
 
I'm seeing a counsellor in regards to my PTSD. I had a near death health scare in the summer of '07.  Post traumatic stress is something I'm dealing with now because of that.  I've also been put on Zoloft.  An anti-anxiety/depression med.  I start it tonight.  I'm nervous!  I hope it helps.  I need relief.  That's the treatment I'm getting.
 
Do you notice that your bad weeks correspond with your period? I'm not sure how old you are, or if you've already gone through menopause.  But that could be why your symptoms go in cycles.


Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/22/2008 7:06 AM (GMT -7)   

Hey Redrose,

I see my rheumy tomorrow and will ask him about referral to a neurologist perhaps, to determine if there is cns involvement.  I hate to add another doctor, but it sounds like good advice.

Thank you for your response

Hester

 

redrose77 said...
Hester, I would suggest a neurologist to test for cns involvement. My rheumy manages my meds but the neurologist has to manage the testing and such.


Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  


hippimom2
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Date Joined Jul 2005
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   Posted 10/22/2008 7:17 AM (GMT -7)   
I know that my brain works differently now that I have lupus. I was much better equipped to handle stress before getting sick and had some really good coping skills to deal with stress. Now my body and my brain just can't handle it and I get both a physical and an emotional reaction to stress. I also notice that I am prone to anxiety attacks now and I never had them before. This past March I finally asked my doc about something for anxiety and he prescribed some Xanax that I could take for the anxiety attacks. It's not something I take everyday, but it's nice to have it around for when I need it. The stinky thing about lupus is that it affects so many parts of the body.
Diagnosis:  UCTD (lupus) 2006; Raynauds 2006; Sjogren's 2006; lupus symptoms began 2003; UC 2008; CFS 1991; Mono 1985
Meds:  Plaquenil 400mg; Prednisone 5-10mg; Tramadol 100mg 3-4x daily; Doxepin 25-50mg; Prevacid; Evoxac; Steriod Cream and Mouth Rinse for tongue and mouth ulcers; Hydrocodone 5/500 prn for severe pain; Artificial tears

 

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Julesc
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Date Joined Oct 2008
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   Posted 10/22/2008 12:55 PM (GMT -7)   
Hi, I am new to this post. I was diagnosed with SLE in Jan 2001. I went along ok until October of 07 when I had a major flare and ended up in the hospital in renal failure, with pericarditis and pleurisy. I have had problems with depression most of my life but after being on such high doses of prednisone for the last year. I have found that I am really depressed. I finally got a counselor. I have seen her 3 times. The last visit she informed me that she and her husband were being transferred to Boston. I am going to see her again one last time on Friday and she is going to give me some names for other people. Anyway. I do believe that lupus and depression go hand in hand. I have talked to several of my doctors about CNS and they were all wishy washy about it. I have short term memory problems. and speech problems and anxiety and tons of self loathing.With the prednisone I have had to deal with the moon face for the last year. It has been hard since I am 34 and single and my looks were the one thing I was always sure of. Anyway I spend most days alone until my son comes home from school and my mother comes home from work but they too have their own issues. Anyway it is nice to find other dealing with similar issues.

redrose77
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   Posted 10/22/2008 1:56 PM (GMT -7)   
I would see a neurologist if I were you Julesc. They are the ones who deal with cns issues and if your neurologist isn't experienced with lupus then you need to find one who is.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, now cellcept


Lynnwood
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   Posted 10/22/2008 6:24 PM (GMT -7)   
In some cases cognitive involvement does not show up in an MRI, thus there doesn't seem to be anything a neurologist can do. You can get an exam by a neuropsych - they have you perform tests (written, verbal, etc.) and can draw medical conclusions from that about cognitive involvement from the AI disease.

Despite a clear MRI, I was able to get a neuropsych test that proved to SSD that I have actual cognitive issues that prohibit me from working.

Of course, that has nothing to do with depression -- I know we usually have depression along with chronic disease, but I don't have any evidence that an actual mental change in that area is cause by lupus itself -- basically since we don't know how to slice & dice the brain yet to see where depression comes from, I don't think we have the technology to determine if they're related or not.

Lynnwood, Co-Moderator: Lupus Forum
SLE(’00), Sjogren's Syndrome, Raynaud's Syndrome, SAD, Depression, Herpes Simplex 1
Piroxicam, Plaquenil, Prednisone(was 15mg, now 8mg), Cellcept, Xanax, Trazodone, Boniva(3mth shot), Wellbrutrin SR, Valtrex
Links: DIAGNOSING LUPUS (4 of 11), LUPUS INFORMATION, LUPUS RESOURCES, Donate to HealingWell, Drug Interactions

Post Edited (Lynnwood) : 10/22/2008 7:27:10 PM (GMT-6)


oldhippyrebel
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Date Joined May 2008
Total Posts : 58
   Posted 10/23/2008 8:21 PM (GMT -7)   
Hester
My Dr, told me that my lupus had caused my depression. It was a very, very dark place I've been in treatment for a little over a year & half. My lupus has been attacking my nerous system. I had gone back to school after being laid off, making the honor role then it got to the point I couldn't tell you what I had just read, let a lone remember when I had test.

I had to make list of thing to remind me of what I needed to get done around the house. I've also changed in what I've focused on around the house. I'm 57 years old and I grew up on a farm but mowing the yard was all we ever did and that is all I ever did in my yard but this summer I got to where I would see something out side and I had to go take care of it and fix it up. I had to pull of a chair but I keep after it. I really don't understand it. There were things I could do in the house but I had to be out pulling weeds, triming bushes and all that kind of stuff. I don't understand why I've gotten so focus on that stuff, I couldn't stop myself. Still can't I just don't understand it.
Fibro since 97, Lupus since 99, neuropathy and other nerve damage.
On to many Meds to list, Finally got a date for SSA of July 1 after to many years of fighting for a hearing.


Serina
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Date Joined Aug 2008
Total Posts : 431
   Posted 10/24/2008 8:53 AM (GMT -7)   

Thank you for sending this response.  I feel for you and wish that I could do something for you.  your lack of memory sounds like me.  but it comes and goes for me.  some times I can think pretty good, and remember things, and other times I can't.

I think maybe that enough research into Lupus causing mental problems has not been done.

this is a day of not being able to think well.  My mind seems flighty unable to focus on things.

thanks again Hippie

Hester

oldhippyrebel said...
Hester
My Dr, told me that my lupus had caused my depression. It was a very, very dark place I've been in treatment for a little over a year & half. My lupus has been attacking my nerous system. I had gone back to school after being laid off, making the honor role then it got to the point I couldn't tell you what I had just read, let a lone remember when I had test.

I had to make list of thing to remind me of what I needed to get done around the house. I've also changed in what I've focused on around the house. I'm 57 years old and I grew up on a farm but mowing the yard was all we ever did and that is all I ever did in my yard but this summer I got to where I would see something out side and I had to go take care of it and fix it up. I had to pull of a chair but I keep after it. I really don't understand it. There were things I could do in the house but I had to be out pulling weeds, triming bushes and all that kind of stuff. I don't understand why I've gotten so focus on that stuff, I couldn't stop myself. Still can't I just don't understand it.


Lupus diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008
 
******
aspirin, multivitamin, Arthrotec , Meclazine ,  plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid,  Amlodipine, Crestor, Lasinopril, Plavix, phenagrin,  Restasis  

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