I have small fiber neuropathy in my feet. This type is not evident using convention EMG testing. I had to have a punch skin biopsy on my foot and on the thigh. This takes all the layers of the skin and counts the nerve endings. Anyway, in addition to this I had every blood and urine test performed in testing for disease causes of small fiber neuropathy. It came down to two possibilities and the only way to confirm a diagnosis was to to do a sural nerve biopsy.
I was also concerned about
the permanent numbness issue since I already have a lot of it and did not relish having more. My neurologist was quite comfortable in leaving the decision up to me. He said that he was 95% confident that my neuropathy was caused by one disease and not the other. He also said that the nerve biopsy would not change my treatment or anything.
I do know that there are a couple diseases that really can only be confirmed/diagnosed by nerve biopsy. It that your case?
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.