I too was surprised to see a doctor would prescribe this drug to a lupus patient. When I looked it up on the Mayo website it says Sulphasalazine is a sulfa based (of course) drug used to treat patients with RA. I hesitated to post, but everything I have read states that anyone with lupus should avoid sulfa based drugs like the plaque. There is quite a bit of information on the LFA website as well, I'm adding the link here for anyone who wishes to read. http://www.lupus.org/webmodules/webarticlesnet/templates/new_empty.aspx?cx=016941646516273541596%3Aivv9xkjkidg&cof=FORID%3A11&q=sulfa+based+drugs#1001
I was prescribed this drug, but for RA/potential IBD, not for SLE. As others have pointed out, it is quite common to have a reaction to this drug because of the sulfa base. I had a horrible reaction, although it doesn't appear right away. I was taking it for 5 weeks before it dropped my platelets way low (dangerously low) and caused a rash from head to toe. My rheumy took me off it immediately and told me to avoid all sulfa drugs from here on out. He kind of put me on it because I think for insurance reasons I had to fail a traditional DMARD for RA before he could put me on a biologic, and at the time I did not want to take methotrexate. this drug has helped many people, though, so it may do wonders for you. Everyone is different, I would just recommend that you follow up with your doctor routinely, and take your blood work seriously, as this drug is infamous for dropping blood counts.
I have it in my own record that I am allergic to sulpha drugs. I tried to take them for a kidney infection, but they make me sick, makes me have nausea, dizziness, and woozy.
So I best add this to my list of things to ake to the Rheumy.
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