My only experience with Methotrexate is that for the first few months of taking it , was wonderful. I was near abouts symptom free sometimes, and even then the symptoms were not that bad.
Then in May of this year I began having a dark depression, was really bad. then it went away, and then it came back. My doctor stopped the methotrexate and I am not taking anything now but folic acid for mouth sores, which has no side effects, and have almost no mouth sores.
will see what happens when I get back to the rheumy and see what he says. He is fickle this doctor. First he told me I didn't have lupus even though I had the blood test to prove it. he told me I had sjogren's. then he told me that I did have lupus and took me off plaquenil and started me on methotrexate because I had a stroke, and at that time he told me that Lupus could have caused the stroke. Now he is back to saying I do not have Lupus. I might need to get myself a new rheumy.
Hope your day will be good to you
Lupus diagnosed 1996, Fibromyalgia diagnosed 1996, Heart by-pass 1998, breast cancer 2000, stroke2002, vascular surgery 2005, heart attack in 2007, and had a stint put in, Sjogren's Syndrome 2008, Stroke 11-4-08
aspirin, multivitamin, Arthrotec , Meclazine , plaquinil, Metoclopomide, Doxepin , Metoprolol, synthroid, Amlodipine, Crestor, Lasinopril, Plavix, phenagrin, Restasis