Do the meds age you prematurely?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

elcamino
Veteran Member


Date Joined Sep 2005
Total Posts : 1744
   Posted 10/14/2009 11:54 AM (GMT -7)   
Hi everyone.  I've been taking mtx and enbrel for RA for several years now.  They work wonders for my joint symptoms.  Lately, though, when I look in the mirror, I look old and haggard.  I'm only 41, but I look like I'm in my 50s already.  Perhaps I'm just overly tired, but I'm sure these drugs have a major impact on my body as well.  Perhaps I need to start taking some vitamins too?  And get more sleep!
 
Any advice?
 
El
Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Lupus
Current Meds: Enbrel, Methotrexate, nexium, tramadol, nasonex, Nifedipine, Folic Acid, Tylenol PM


redrose77
Veteran Member


Date Joined Sep 2005
Total Posts : 2573
   Posted 10/14/2009 1:18 PM (GMT -7)   
I have no idea what to suggest except a good moisturizer and avoiding the sun. Sun damage ages the skin so if you spent a lot of time in the sun when you were younger then you have your answer.
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sjögren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, cozar
"Those who dream by night in the dusty recesses of their minds wake in the day to find that it was vanity: but the dreamers of the day are dangerous men, for they may act their dreams with open eyes, to make it possible." T. E. Lawrence


okie
Veteran Member


Date Joined Dec 2006
Total Posts : 2818
   Posted 10/14/2009 4:16 PM (GMT -7)   

Hi El, Well the first thing I would suggest is that you don't say old and haggard and looking old like your 50's! Wait let me get my rocker I'm 52 lol.

Seriously though I'm not sure that the meds are doing it but stress pain chronic illness does put wear and tear on the body. There are some books out there that you can get that talk about living with a chronic illness. You may just go down to the library and check into a couple of them. I wouldn't suggest buying anything since I haven't read them. You might try doing something like getting a new shade of make up. You know the weather is changing and that can cause depression as the sun goes down earlier. Maybe a new hair style or color. I don't know if you exercise or not but I always feel better if I get on a tread mill 20 min.s 2 or 3 times a week. Just on level 1.5 with my o2 on. I know I didn't answer your question but sometimes the way you think you look has a lot to do with the way you feel physically and just as much psyologically.

Love ya

carol



systemic sclerosis sine scleroderma,sleep apnea,Megaloblastic anemia
what ever that is.
 
 


MMMNAVY
Veteran Member


Date Joined Jul 2006
Total Posts : 6927
   Posted 10/14/2009 4:44 PM (GMT -7)   
When I was 29 a woman said you are about my age right? She was 52 at the time.
Forum Co-moderator - Crohn's Disease/Thyroid Disorders:_All comments have the caveat contact your local health care provider.

I will find a way or make one. –Phillip Sidney 1554-1586

All that I am and all that I shall ever be, I owe to my Angel Mother.

The Bucket List- Have you found joy in your life?  Has your life brought joy to others?

Make sure your suffering has meaning…


crazykitty
Veteran Member


Date Joined Jul 2009
Total Posts : 4796
   Posted 10/14/2009 6:54 PM (GMT -7)   
Hi El, I am also on Methotrexate. I'm 57 and look my age, somedays I feel like 90.

Stress can age a person in a hurry, so if you are feeling stressed out, doing relaxation therapy
will help. I take long leisurely soaks in a hot bath, do deep breathing exercises and try to
get a long walk daily. Like Okie said "stress,pain, chronic illness puts wear and tear on the body.

I agree with Redrose about avoiding the sun and using a good moisturizure. I always use
sunscreen. It is also important to keep hydrated. Take time for yourself daily.

Hugs

Robin
MCTD, Fibromyalgia, Raynauds, Osteoarthritis, Osteoporosis, Degenerative 
 Disc Disease, Hypertension, Migraines and Pseudothrombocytopenia MEDS: Methotrexate, Savella,Flexeril,Diltiazem, Boniva, Vitamins 


cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/14/2009 7:08 PM (GMT -7)   
They sure make you feel that way, esp. when they wear off.  Well, some things I noticed was that my hair looks more overall gray and thinner on plaquenil, but that is likely due to bleaching and spread of my vitiligo through my insistent use of hair dye to cover it. 
 
As for wrinkles--skin hair and nail vits help.  Hormones make a big difference.  Estrogen seems to make you have less wrinkles and look younger, in myself and people I know. Your hormones might be out of balance.  A really good treatment for wrinkles is to take a vitamin A gelcap and poke a hole in it and squeeze out the oil and put it on your wrinkles. I also use an elastin and collagen cream daily when Im' not using something medicated. There are lots of cheap moisturers that are really good these days.
 
Prednisone has made my face puffyand fuzzy, and then theres the rash and spidering. But makeup and hair removal does wonders.
 
Then I slouch because my spine is so curved and messed up. and pain makes you look old.
 
I see an ob/gyn who is a wellness doctor. She regulates my hormones and vitamins and provides dietary guidance.  It helps.
 
Just plain having energy can make a big difference too. the old young as a you feel thing.  Sometimes I need a change. I went to dying my hair darker instead of lighter so I wouldn't have to do it as much, and it really helped, as did a haircut and some new clothes. But right now I look old, I'm just so worn out.
 
You might try the wellness doc if you feel up to it.  You might have some deficiencies. 
 
Maybe its just the meds and disease wearing you down a little. This isn't much of a cheer up reply, but I know how you feel. My grey roots are gleaming right now and I don't have the energy to do anything about it.
Love, Marji
Ills--Sjogrens-Lupus cond., AI polygland. dysfunction 2, hyper/hypopigment, scoliosis,kyphosis,stenosis, deg.,O.A.,spine surgeries, salivary/lymphectomies, NASH, COPD, RLS, UT/GI bleeds, hystero, brain/nerve damage,TB
Meds--INH,Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, HRT and Lidocaine patchs, Voltaren gel, Klonopin, Vicodin, Restasis, Albuterol, steroids


elcamino
Veteran Member


Date Joined Sep 2005
Total Posts : 1744
   Posted 10/15/2009 5:39 AM (GMT -7)   

Thanks all.  I avoid the sun like the plague, as it has a similar effect on my flares as it does for most of you.  I haven't been exercising regularly, though, and desparately need to start doing so again.  Perhaps you've given the motivation to do so.  I just have a hard time finding the time--I work full-time and have twin 7-year-old daughters.  I think what makes me look the oldest is the dark circles under my eyes.  I'll invest in a better concealer than what I currently use.

All of you have given me some very good ideas--love the vitamin A gelcap idea.  Perhaps I'll go back to Mary Kay make-up.  I used to use it and the entire facial cleansing system really rejuvenated my skin a lot.

Best to all of you!

Elcamino


Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Lupus
Current Meds: Enbrel, Methotrexate, nexium, tramadol, nasonex, Nifedipine, Folic Acid, Tylenol PM


crazykitty
Veteran Member


Date Joined Jul 2009
Total Posts : 4796
   Posted 10/15/2009 6:11 AM (GMT -7)   
El, I also use the Mary Kay cleansing Time Wise microdermabrasion refine and replenish
and really think it is great!

Robin
MCTD, Fibromyalgia, Raynauds, Osteoarthritis, Osteoporosis, Degenerative 
 Disc Disease, Hypertension, Migraines and Pseudothrombocytopenia MEDS: Methotrexate, Savella,Flexeril,Diltiazem, Boniva, Vitamins 


PattyLatty
Veteran Member


Date Joined Mar 2006
Total Posts : 2570
   Posted 10/15/2009 9:11 AM (GMT -7)   
And if you don't smoke, don't start. Smoking will age a person perhaps more than anything else.
SLE, fibro, renauds, restless leg, hiatal hernia, double vision, migraines, costocondritis.

prednisone, plaquenil, leflunomide, neurontin, synthroid, triamterene, actonel, niaspan, tri-est, cymbalta, tricor, acifex


momto3
Veteran Member


Date Joined Nov 2006
Total Posts : 1331
   Posted 10/15/2009 10:07 AM (GMT -7)   
Hi El..I also take the MTX and have for several years, and yes I think it takes a toll on hair and skin.  After all it is chemo, even if it is a low dose.  I'm also having the same issue as you, with the exception of the dark circles and I'm 38. In the past year my skin has really aged, and I've always tried to take care of it, sunscreen etc.  I went off of the MTX for about a month recently and to my horror, I had the worst rashy red face ever!! So, I guess the MTX is good for at least that, because once I started taking it again, the redness faded, so I guess it is good for something besides joint pain!
 
Someone mentioned Mary Kay? I used to sell/use the products and hands down they really are the best on the market, as far as skin care is concerned. 

cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/15/2009 8:07 PM (GMT -7)   
Green peppers applied under the eyes are supposed to work really well to get rid of the circles, something about the vitamn K in them. They even made creams out of them. I use a powder based makeup instead of the creams because they weight down my skin and cause more wrinkles, I feel. They also clog my huge pores. I think the powders cover better with less, but this is just my two cents. I haven't used anything but a powder foundation--like covergirl tinted powder--since I have been 14 because I had a friend who was a makeup artist and warned me about liquid and cream foundations and heavy creams. I'm sure alot has changed in 31 years, but I only have a few tiny crows feet after all that time. Don't know if its just because my face is so puffy and round now, maybe!;) I've tried all kinds of foundation on my vitiligo and hyperpigmentation to try to even it out and the nly thing that ever covered it was the sally hansen spray on for your legs, which also lays on top of the skin, though its greasy and comes off. Any suggestions from you cosmetologists on possible products would be greatly appreciated--just email me. I will try anything at this point.
Love, Marji
Ills--Sjogrens-Lupus cond., AI polygland. dysfunction 2, hyper/hypopigment, scoliosis,kyphosis,stenosis, deg.,O.A.,spine surgeries, salivary/lymphectomies, NASH, COPD, RLS, UT/GI bleeds, hystero, brain/nerve damage,TB
Meds--INH,Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, HRT and Lidocaine patchs, Voltaren gel, Klonopin, Vicodin, Restasis, Albuterol, steroids


Bsime
Veteran Member


Date Joined Apr 2006
Total Posts : 1298
   Posted 10/16/2009 11:04 AM (GMT -7)   
El,
 
I don't think meds age you but your disease(s) and other conditions do.  If it is any comfort I am much older and when I was at my worst and near death in Dec 2005 I went from being a very young 63 to looking like I had come out of the death camps.  I lost 40 lbs of muscle in a week, was dying of AI induced hepatitis, had other organ involvement, and infections.  If you saw me today I now look healthy and much younger (or so I am told) than my age.  I frequently am addressed as "young man" by people who are actually younger than me....it is fun to correct them.
 
Focus on the basics of good health and nutrition and try to be optimistic.  Our bodies have a great capacity to heal but you have to help them and give them a chance.  Having a positive and optimistic attitude is more important than you imagine.  And try to stay as physically active as you can.
 
Hang in there and don't worry so much.
 
Bill
MCTD (lupus, scleroderma, polymyositis).  Diagnosed 2005.  Kidney, liver, GI tract, dysphagia, raynauds, Barretts esophagus, quadriplegic in 2005.  Recovered and now active in skiing, tai, chi, hiking, golf.  Meds: prednisone 2.5mg, imuran 25mg, amlodipine, benazapril, omeprazole, potassium, folic acid, vitamins, maxide and various supplements and vitamins.
 
Remain optimistic and you can overcome the odds.


MJLD
Veteran Member


Date Joined Jul 2007
Total Posts : 1048
   Posted 10/16/2009 4:09 PM (GMT -7)   
I can tell you from a nursing and a personal point of view that prednisone does, in fact, accelerate the aging process.  In long term, moderate to high doses, it thins the skin and bones,  delays healing, prematurely ages your cardiovascular system and the list goes on.  (Ask your Physician about this)  This is precisely why when a women is about to give birth prematurely they are often given a big dose of steroids,  it excelerates the aging process and therefore the development of the baby!
 
I would like to bring up another point of view.  I read somewhere that people with Autoimmune disease tend to gray prematurely.  I can not vouch for the validity, but I can say, on my dad's side of the family there are tons of autoimmune diseases,(rheumatoid, lupus, chrohns/coli***) and my dad's family grays extremely prematurely, like in the teen years and they age quickly.  Maybe it's a coincidence???  Has anybody else noticed this in your own family?  Judy

cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/16/2009 6:56 PM (GMT -7)   
I know vitiligo is an autoimmune disease of the skin that causes you to lose pigment in skin and the hair growing on it and even affects the eyes. It runs with all the other ai diseases so there is definitely some autoimmune basis for some forms of skin and hair whitening. Also, I think endocrine problems might contribute, so back to steroids and hormones too so a double whammy...
Love, Marji
Ills--Sjogrens-Lupus cond., AI polygland. dysfunction 2, hyper/hypopigment, scoliosis,kyphosis,stenosis, deg.,O.A.,spine surgeries, salivary/lymphectomies, NASH, COPD, RLS, UT/GI bleeds, hystero, brain/nerve damage,TB
Meds--INH,Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, HRT and Lidocaine patchs, Voltaren gel, Klonopin, Vicodin, Restasis, Albuterol, steroids


momto3
Veteran Member


Date Joined Nov 2006
Total Posts : 1331
   Posted 10/18/2009 10:31 AM (GMT -7)   
Cured...I also have some of the white spots you mentioned on my hands, do you know any treatments for it?

cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/18/2009 7:14 PM (GMT -7)   
Hi mom--
You really need to get to a good dermatologist for this problem--someone that does laser and light therapies--not because you will necessary use them, but because the docs that do that stuff are generally very knowledgeble about vitiligo and other pigment problems. Most people without lupus will use some kind of special light therapy, but if you have lupus that is out. But first, you need to make sure what is going on. A fungus called tinea versicolor causes the same problem and can be treated with head and shoulders shampoo rubbed in as a crem and left on for fifiteen to twenty minutes. Then the color starts to come back. If it s not a fungus or other type of infection (they can do scrapings and there are other tests) then it can be pigment loss, especially if the hair grows in white on the white patches, thats a sign of 100 pct depigmentation. Pigment loss,or vitiligo, can be a sign of rather serious endocrine problems or can be hereditary and autoimmune based, where the immune system attacks the skin. Even if it is endocrine based, usually the endocrine problems are autoimmune based, like hashis or Addisons disease, though TB and some other infections that attack the endocrine can be to blame. Blood and antibodie and other tests are run by the dermatologist to determine the cause. Vitiligo from endocrine tends to be really patchy, making the skin look moth eaten or freckled, while autoimmune vitiligo tend to occur in big huge patches, which is often easier to cover up with makeup or dyes.

Treatments involve cancer med immunossuppresants like protopic cream, generally used with light therapy, though that is out for lupies. The cream can work on its own without light, but takes longer. New research is being done into black pepper oil being used in a cream. It is extremely fast and effective, but is not safe. Clinical trials are taking place with formulations and I have no doubt that this will be the cure of the future. White mice repigmentedin a few weeks with treatments three times a week, but also developed some forms of cancer, so more work needs to be done (also,they used an extremely strong solution, assuming it would be safe since it is an ingredient commonly used in perfumes and arthritis creams). It also makes any medicines you take much stronger, so that is a problem.

If you have the endocrine type problem, adjusting your endocrine sytem should correct the problem. Dermatologists are great and will often diagnose and treat endocrine problems that affect the skin very effectively, where an endocrinologist wont do anything until you are terminal or need surgery.

I'm sorry this is so long. You can email me and I can hook you up with a good forumwith financial resources to help you get treatment if your insurance will not pay. it is important to keep the vitiligo from spreading to your face and around your eyes and it can harm you eyes when the eyelashes go pure white they also go completely straight and scratch and poke you eyes. eye problems when the vit is there are common and ryou can lose eyelashes and eyebrows. I think eye color can be effected though not sure.

Take care and get in to the dermatologist. Serious infectious diseases can cause these problems too. The longer you have it, the less likely it is to go away.
Love, Marji
Ills--Sjogrens-Lupus cond., AI polygland. dysfunction 2, hyper/hypopigment, scoliosis,kyphosis,stenosis, deg.,O.A.,spine surgeries, salivary/lymphectomies, NASH, COPD, RLS, UT/GI bleeds, hystero, brain/nerve damage,TB
Meds--INH,Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, HRT and Lidocaine patchs, Voltaren gel, Klonopin, Vicodin, Restasis, Albuterol, steroids


momto3
Veteran Member


Date Joined Nov 2006
Total Posts : 1331
   Posted 10/21/2009 9:13 AM (GMT -7)   
Hi Marji,
 
I went to a Derm over the summer and while I was there, she put some kind of blue light over my arms and hands and determined that it wasn't a fungal infection and told me that the only way to get rid of my hyperpigmentation was to do the light therapy.  She said it was caused by sun damage?? Even though I have some areas on my legs that never see the light of day! I think it sounds like the Vitiligo that you described, but she never tested me for anything and it was a very short office visit, to say I was dissapointed is an understatement! My insurance paid for that visit, however it will not pay for the light therapy treatments since it is considered cosmetic.
 
Have you had the light therapy treatments by chance? I'm afraid if I do them, I will end up with a sunburn since I take the Methotrexate, and if I stop taking the MTX, I get a really horrible face rash, and the MTX keeps it under control,  so I guess I need to find out how strong the light therapy is? The derm never mentioned any causes except for sun damage and it seems all skin issues according to her are caused by the sun!
 
Thank you for the wonderful information!
New Topic Post Reply Printable Version
Forum Information
Currently it is Sunday, December 04, 2016 9:31 AM (GMT -7)
There are a total of 2,732,558 posts in 301,031 threads.
View Active Threads


Who's Online
This forum has 151190 registered members. Please welcome our newest member, nakertar.
268 Guest(s), 8 Registered Member(s) are currently online.  Details
George_, sheepguy, Bololidat, Almost a 10, Girlie, Huddie, Mustard Seed, trumpet123


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2016 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer