+ANA a fibromyalgia indicator ?

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Date Joined Jun 2008
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   Posted 11/19/2009 11:38 PM (GMT -6)   
Saw rheumy today.  CRP back to normal, (yay) though liver enzymes were mildly elevated.  ANA is back to positive, but only 1:320.  Today she tells me the ANA could be positive from the Fibro.  (Other markers for Lupus, Sjogren's, RA remain negative).  Not what she has said all along - and not something I've come across before.  Anybody else?  
Last time she told me if my ANA was negative again (which it was for the first time in 3 yrs recently after 10 mos. on Plaquenil) it would mean I "no longer have a CTD".   Since it went back to positive - she thinks I should stay on the Plaquenil.  Which is not used in treating Fibro, so why would she say the + ANA could just be reflecting the fibro?     
I have asked on 3 occasions over the last 3 yrs.  if she believed all of my symptoms etc. were strictly from fibro, and she always said no because of the ANA.   I am dizzy from the contradictions, and  I won't be returning to her.   Just wondered if anyone else has heard of Fibro producing a positive ANA?  I know it can be caused by things other than AI disorders, but I've never seen Fibro on that list.  Thanks.
diagnoses:  mono 1972; postviral CFS 1997; fibro 1998; UCTD & osteoporosis 2007; celiac 2009
meds: Plaquenil 400 mg, occasional low dose xanax for sleep aid, artificial tears w/ ointment at night, Advil/aspirin prn and lots of vitamins

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Date Joined Mar 2006
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   Posted 11/20/2009 12:49 AM (GMT -6)   
I would have thought that a person with fibro and a positive ana would indicate that (a) either the person had a false positive ana, or (b) that the person was one of many who have a positive ana with no underlying disease. The fact that the person also had fibro would be a coincidence.

I wouldn't put my house on the line, but I don't think a positive ana can cause fibro.

SLE, fibro, renauds, restless leg, hiatal hernia, double vision, migraines, costocondritis.

prednisone, plaquenil, leflunomide, neurontin, synthroid, triamterene, actonel, niaspan, lyrica, tri-est, cymbalta, acifex

Forum Moderator

Date Joined May 2005
Total Posts : 6946
   Posted 11/20/2009 11:13 AM (GMT -6)   
My rheumy tried to switch my diagnosis from lupus to fibro when my ANA became negative. Which would be the oppsite of what your dr is saying.

If ANA+ meant fibro we'd hear more about it - what we hear now if that fibro has no blood or urine tests that prove it existis.

You can alos pose the question onthe HW fibro forum and see what folks there say!
Lynnwood, Lupus & Sjogren's Moderator
"Life is far too important to be taken seriously" - Oscar Wilde

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Date Joined Sep 2009
Total Posts : 1176
   Posted 11/20/2009 11:48 AM (GMT -6)   
The current American Medical Association viewpoint is that fibro is not an autoimmune disease, so in that case, a positive ANA would not mean anything at all wrt fibro.

There is some controversy about this, however; a number of researchers have found certain antibodies in people with fibro and chronic fatigue syndrome and are now suggesting that fibro MAY be an autoimmune disorder. The following paper is an example:


Fibro is certainly found most often in people who do have autoimmune issues, so it seems to be related in some way.

Autoimmune hepatitis, Hashimoto's thyroiditis, lupus, fibromyalgia, rheumatoid arthritis, celiac disease, asthma, psoriasis, Raynaud's syndrome, hypertension, osteopenia, sleep apnea, restless leg syndrome, GERD.

Prednisone, Imuran, Plaquenil, Lyrica, Cymbalta, Levothyroxine, Atenolol, Cozaar, Mirapex, Zyrtec, Fosamax, Albuterol, Prilosec, CPAP


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Date Joined Jun 2008
Total Posts : 669
   Posted 11/20/2009 2:36 PM (GMT -6)   

Lynn - I will post on the fibro board - good idea.  Pat - rheumy doesn't think the ANA is false positive because of the higher elevations over the years, and the fact that it has come down with Plaquenil tx.   JoAnn - thanks for the link to the article, which is interesting.  Hopefully one day this will all be sorted out.  In the meantime - I think I'll just stay away from doctors for awhile, as well as trying to make some sense of it!  Thanks - Lucy

diagnoses:  mono 1972; postviral CFS 1997; fibro 1998; UCTD & osteoporosis 2007; celiac 2009
meds: Plaquenil 400 mg, occasional low dose xanax for sleep aid, artificial tears w/ ointment at night, Advil/aspirin prn and lots of vitamins

Veteran Member

Date Joined Sep 2005
Total Posts : 2573
   Posted 11/21/2009 2:26 AM (GMT -6)   
I wouldn't avoid doctors I would just find someone who makes some sense instead of someone who changes their story constantly
Dx:fibromyalgia 2002, systematic lupus 2005- definate CNS involvement dxed late 2005, psoriasis 2006, rheumatoid arthritis 2006, PTSD 2007, multiple allergies 2005, migraine, compression fractures T11 & T12, Sj√∂gren's, damaged periphrial nerves 2007, exema
Tx: plaquenil, Enbrel, Tramadol, Singulair, Skelaxin, Baby Asprin, Imuran, Prilosec, lasix, Evoxac, Celebrex, Darvocet when things get too bad, prednisone again, various vitamin/mineral supplements, cozar
"Those who dream by night in the dusty recesses of their minds wake in the day to find that it was vanity: but the dreamers of the day are dangerous men, for they may act their dreams with open eyes, to make it possible." T. E. Lawrence

New Member

Date Joined Apr 2008
Total Posts : 6
   Posted 11/21/2009 8:41 AM (GMT -6)   
I have fibromyalgia.

I have a negative ANA.

That test has little to do with a fibro diagnosis. In fact, a positive ANA could mean that it is NOT fibro, but something else instead.
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