methotrexate question

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kat10
Regular Member


Date Joined Aug 2010
Total Posts : 112
   Posted 8/14/2010 7:57 AM (GMT -7)   
Hello, does anybody know how soon after taking methotrexate you start feeling side effects? Is it immediate or does it take a couple of doses?
 
 

Post Edited By Moderator (aimsgirl16) : 8/16/2010 3:46:04 PM (GMT-6)


Lynnwood
Forum Moderator


Date Joined May 2005
Total Posts : 7019
   Posted 8/14/2010 8:58 AM (GMT -7)   
I believe it is more like a few weeks, but I haven't had it myself. Hopefully a member will come along that has been on MTX.

Cheers,
Lynnwood, Lupus & Sjogren's Moderator
"Life is far too important to be taken seriously" - Oscar Wilde

kat10
Regular Member


Date Joined Aug 2010
Total Posts : 112
   Posted 8/14/2010 11:05 AM (GMT -7)   
Thanks Lynnwood. I am so new to this and every week I start a new drug and I have not been feeling well to begin with.
Kat10

anna24
Regular Member


Date Joined May 2009
Total Posts : 27
   Posted 8/14/2010 12:36 PM (GMT -7)   
I have taken methotrexate for about 5 years now. I had some nausea after the first couple of
months. I take the highest dose allowed - 20 mgs. once a week. Nausea is the only side
effect I have experienced and usually drinking some ginger ale or eating something will help.
SLE, vasculitis, methotrexate, plaquenil, dapsone & the usual supplements

kat10
Regular Member


Date Joined Aug 2010
Total Posts : 112
   Posted 8/15/2010 11:54 AM (GMT -7)   
Thanks anna24, I just started on a 2.5 mgs so I am guessing it is a really low doseage.
Along with prednisone 5 mgs and Hydroxychlor 200 mgs and folic acid. I have not been feeling very well lately as I understand it may take a while before the meds kick in.
Thnka again for the info and advice. :)

jhmom
Veteran Member


Date Joined Oct 2004
Total Posts : 2244
   Posted 8/16/2010 10:02 AM (GMT -7)   
Hi Kat,

It took several months for it to kick in for me and I am on 7.5 mg a week. Be sure to take it with your biggest meal. I usually don't have nausea unless I don't have enough on my stomach but if you still feel sick there is a medication to help with that, I can't remember the name but I am sure your pharmacist or doctor will know.

The only other symptoms I had was when we increased my dose to 12.5 mg, within a couple of days I was sick, felt lethargic, etc. Once I went back down to my original dose those symptoms went away.

I pray it kicks in soon for you and you begin to feel better! Take care
Stacie
Trust in the Lord with all thine heart, and lean not unto thine own understanding ~ Proverbs 3:5 ~

DX: Lupus, Sjogrens, Raynaud's, Hashimoto's and Celiac Disease
RX: Imuran, Plaquenil, Methotrexate, Flexeril, Piroxicam, Levoxyl, Folic Acid and Tramadol (as needed) and magic mouthwash ( as needed for mouth sores)

kat10
Regular Member


Date Joined Aug 2010
Total Posts : 112
   Posted 8/16/2010 4:51 PM (GMT -7)   
Hi jhmon, Thanks, I did not know about taking it with my biggest meal I will do that from now on. This site is so great, I am learning things from nice and helpfull people like you that sometimes you doctor or pharmacist might forget or overlook to tell you. and with being newly diagnosed I was not ready for all the questions I would have. How long have you been on the methotrexate for? I hope I am feeling better soon too, God knows I have felt sick long enough. God bless
Kat

jhmom
Veteran Member


Date Joined Oct 2004
Total Posts : 2244
   Posted 8/16/2010 5:03 PM (GMT -7)   
Hi Kat,

You are most welcome! I know how overwhelming this all can be, but you are doing great, just keep asking questions and learning all you can about your illness. I also suggest you write your questions down and take them with you to your doctor's appt, I have to do that or I would forget yeah

I have been on MTX since Feb 2008 and it took a good 2 months before I could tell it was working, but we are all different so don't give up on it. Feel free to ask more questions. God Bless you too!
Stacie
Trust in the Lord with all thine heart, and lean not unto thine own understanding ~ Proverbs 3:5 ~

DX: Lupus, Sjogrens, Raynaud's, Hashimoto's and Celiac Disease
RX: Imuran, Plaquenil, Methotrexate, Flexeril, Piroxicam, Levoxyl, Folic Acid and Tramadol (as needed) and magic mouthwash ( as needed for mouth sores)

kat10
Regular Member


Date Joined Aug 2010
Total Posts : 112
   Posted 8/16/2010 8:56 PM (GMT -7)   
Hi Jhmom, I just started writing down questions for my doctors appt on thursday. good advice. Thanks! :)

Dreamer1979
New Member


Date Joined Aug 2010
Total Posts : 3
   Posted 8/17/2010 6:57 AM (GMT -7)   
Hi there,
Just found this forum by searching online.
I got diagnosed with Coup De Sabre linear morphea/scleroderma...so wondered if anyone else was dealing with anything like that?
I just started Methotrexate, so any group on here that has MTX experience would be a great comfort too.
Been 2 weeks on 5mg and just went up to 10mg MTX today. Hoping the side effects will be ok.
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