I have had Crohn's Disease for 14 years. In 10/09 I had major surgery (proctocolectomy with perm Ileostomy) about 8 months ago i was also diagnosed with SLE. Hoping that is drug induced Lupus, but so far it is holding strong with SLE. all test are still positive. I do take 400 mg of Plaquenil daily fr the Lupus. Working well for the joint pain but seems to be causing GI upset, bloat and liquid stool.