ANA 1:320 first homogeneous, and and then speckled

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

SoSt9
Regular Member


Date Joined May 2012
Total Posts : 227
   Posted 8/22/2012 5:36 AM (GMT -7)   
Hello, I have a question. First, I apologize for any typos. My Internet went out yesterday, and and I am using my phone.

Okay, I have been going to several doctors (which seems par for the course), and I got a peek at the blood results from my latest rheumy yesterday (but the dermatologist who works through the same hospital gave me the result). I had a lot of tests run, and but the dermatologist only gave me the ANA result. It was 1:320 speckled. I believe he said lightly speckled, and but I didn't quite catch what he said and he didn't want to repeat himself. When I first had blood work regarding the problems I have been having, my results were still 1:320, but they were homogeneous. This was done back in March, I believe. This latest test (the speckled one) was drawn in July. Why would the pattern change like that? In between the tests I did start to feel better, and I am having new and more intense symptoms (but I don't consider myself severe by any means) including mouth rashes. Is it possible that there is more than one thing going on, or is it possible that the initial results were wrong? I am just being too curious, I suppose. I don't see my rheumy for about 5ish weeks to get the official results. Any thoughts?

couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 12530
   Posted 8/22/2012 10:32 AM (GMT -7)   
I've read somewhere that the patterns can change. You may have something developing in addition, but only the Rheumy can determine. You're just going to have to wait for your discussion.
Joy
When life throws you lemons....
Pick them up and throw them right back at them! :))

SoSt9
Regular Member


Date Joined May 2012
Total Posts : 227
   Posted 8/22/2012 10:02 PM (GMT -7)   
Thanks Joy. :)

I guess I am just stressed. So many things are going on. I have been afraid that blood work would either come back completely negative (like the first rheumy i saw, but I know where he sent the blood work, and I have never cared for that lab). I didn't expect the pattern to change on me like that . I am now dying of curiosity of what the "inconsequential" results my derm didn't want to give me. I am too nosey.
Lupus? Fibromyalgia? Sjogrens? RA? Who knows. Currently in a holding pattern.

Frequent lurker... Part time poster.

Post Edited (SoSt9) : 8/22/2012 10:23:29 PM (GMT-6)


couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 12530
   Posted 8/23/2012 1:41 PM (GMT -7)   
I'm stressed too. I think it's part of the lupus lifestyle. :)

I'm coming to terms with the frustrations of this new life myself.
Joy
When life throws you lemons....
Pick them up and throw them right back at them! :))

sparkyfox
New Member


Date Joined Aug 2012
Total Posts : 2
   Posted 8/24/2012 8:36 AM (GMT -7)   
My ANA was 1:80 and speckled was what my MD said but I don't really understand the results, does that indicate a positive ANA?

lucysgd
Veteran Member


Date Joined Jun 2008
Total Posts : 663
   Posted 8/24/2012 1:54 PM (GMT -7)   
My ANA has remained positive for nearly 5 years.  I think the highest was 1:1280, (at which point I was started on Plaquenil) with the lowest at 1:80.  Generally it stays in the 1:360 range.   The majority of the patterns are nucleolar.  Occasionally, speckled and a time or two homogenous and maybe once diffuse.  Also have had two patterns indicated on one test more than once. 
 
I've given up trying to figure out what it means when the patterns change or two are indicated at once.  If anyone has ever gotten a rheumy to explain what that means, I would love to hear it! 
 
Lucy 

Lynnwood
Forum Moderator


Date Joined May 2005
Total Posts : 5790
   Posted 8/24/2012 2:17 PM (GMT -7)   
Check out our Lupus Resources thread (link in my signature in case you don't know where it is) for a good explanation of ANA values & patterns.
Lynnwood, Lupus & Sjogren's Moderator
DIAGNOSING-LUPUS & LUPUS-RESOURCES
"Life is far too important to be taken seriously" - Oscar Wilde

lucysgd
Veteran Member


Date Joined Jun 2008
Total Posts : 663
   Posted 8/24/2012 4:12 PM (GMT -7)   
The information there is very helpful in explaining the pattern associations, but it doesn't address having more than one pattern per test, or a pattern change from one test to the next.  I have wondered if it's more a feature of MCTD......or?   

SoSt9
Regular Member


Date Joined May 2012
Total Posts : 227
   Posted 8/27/2012 2:50 AM (GMT -7)   
I agree with lucysgd. :) I have been reading anything I can about this, and the links provided do show a lot of very helpful information. My problem is that what is not included in the Lupus links is information about changing patterns (or mixed patterns) and what it might or might not mean. Even on the net there us conflicting information.

I suppose I am trying to see if the change in pattern might mean that I do actually have something going on. Originally, my primary care doctor said I did not have Lupus because even though I had a positive ANA (1:320 Homogeneous), my ds-DNA was negative. She said that it meant it was not Lupus. Since then, I have been through numerous doctors (ordering blood tests and everything else under the sun), including two dermatologists, two ENTs, a neurologist (and maybe another who specializes in movement disorders soon), two ophthalmologists, and two rheumatologists. This has been frustrating, but for the most part,, I have remained quiet here. There are so many who are worse off than I am.

After the first positive ANA and the negative ds, my dr did send me to a rhuemy. He did a lot of blood work, but it ALL came back negative. To me, that was odd. There were things that should have come out skewed (because of how I am), but none did. Because of this, he said that I did not have anything except a connective tissue disorder called Ehlers-Danlos. I went for a second opinion, and that rheumy said that I did not have ED, but I did have hypermobility. His is the blood work that has the changed ANA. I do not know any of the other results.

After the first positive, then a negative on everything, it was a huge letdown (not that I want to have anything, but I do want to know why I feel the way I do). I have been afraid that this round of blood work will lead me to another dead end. Knowing that I have a positive ANA again and a change in pattern has me confused, but I am not scared-confused. I mostly want to know the general consensus. I also want to know why I went from positive one pattern, to negative and then back to positive, but with a different pattern.

Sorry about being wordy. It is late ad I tend to do that.
New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, November 22, 2014 7:57 AM (GMT -7)
There are a total of 2,275,120 posts in 252,893 threads.
View Active Threads


Who's Online
This forum has 158641 registered members. Please welcome our newest member, Bijoy.
305 Guest(s), 8 Registered Member(s) are currently online.  Details
buckeyecrohnie, PeterDisAbelard., Utahgal, turpT1a, ninjakiller1, Ichabod, Old Mike, 1039smooth


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest  Follow HealingWell.com on YouTube
Advertisement
Advertisement

©1996-2014 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer