Can anyone share their experience with Methotrexate ?

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BreRosie
Regular Member


Date Joined Jun 2016
Total Posts : 47
   Posted 10/17/2016 5:55 PM (GMT -6)   
I saw my rhuemy today and since I keep flaring he wants to add methotrexate to my list of medications ,Iam taking hydroxychloriquinne, prednisolone and gabapentin already. I would be grateful if those of you who have used it or are currently on it could tell me about how it affected them. Thank you.

couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 10/17/2016 7:28 PM (GMT -6)   
I was one of the unfortunate few who couldn't take it. I had adverse reactions to it. Severe stomach pain, diarrhea, vomiting, and chills.

I'm allergic to several drugs so it was nothing new to me.
Joy
Lupus, RA, Fibromyalgia, Glaucoma, Asthma, Hypothyriodism, Sleep Apnea, Depression, Allergies, diabetes, and benign familia tremors

When life throws you lemons....
Pick them up and throw them right back at them! :))

BreRosie
Regular Member


Date Joined Jun 2016
Total Posts : 47
   Posted 10/18/2016 3:26 AM (GMT -6)   
I've read a lot about it and some of what I've read has made me nervous. Things like people being really sick to their stomachs and hair loss. He wants me to start the pill form and folic acid with it as I guess it lessenes the side afffects. I took a drug called bromocriptine for a little over a year for a sm tumor in my pituitary gland and for a week I was really sick .I was about to call the doc and tell them to give me something else because I couldn't handle it but then my body started to adjust. I'm hoping that this stuff is not as bad for me and that I'll adjust quickly. I going to start taking it this Friday since its only once a week and hope that by Monday I feel "normal" enough to function. Thanks for replying couchtator!
Thyroid disease 2015, Lupus and Sjrogrens July 2016 and Fibro October 2016
I'm Just gonna keep on smilling

Butterflake
Forum Moderator


Date Joined Jun 2006
Total Posts : 1646
   Posted Yesterday 2:27 AM (GMT -6)   
Hi BreRosie. I'm sorry to hear that you're flaring again. It seems most rheumies follow the same plan on medications to treat Lupus. They start with hydroxychloroquin, then add methotrexate, followed by immuran, etc, but remaining on hydroxychloroquin.

I took methotrexate years ago and I can't remember how long I took it, but I do remember that it gave me great relief with no side effects. Eventually my flares and symptoms returned so I had to move on to Immuran which didn't help me at all. And so it goes. I've been on hydroxychloroquin for over 10 years with many meds added, then discontinued, and other meds tried. Since everyone reacts to medications differently you may take methotrexate and find that it works well. I know it's scary trying more meds, but in my opinion it's better than flaring. Please feel free to let us know how you're feeling. Love, Butterflake
SLE '05, Sjogren's, Fibro, Raynaud's, major depressive disorder, CVID (Common Variable Immunodeficiency), Hypertension, Osteoporosis, CNS problems, GERD, angina, 1st stage kidney disease. Many meds: better living through chemistry
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