Family members with RH neg. or Pos. blood?

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mom46
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   Posted 3/16/2007 6:07 AM (GMT -7)   
Hi Everyone,
  I don't know if this is a factor for lupus or not, but a couple of you have mentioned RH blood in your family in another post. My mom had RH neg blood as well and 2 of my brothers, but I have O+ blood. Who else has this blood type in their family?
  I tried to find some info on this, but couldn't. I did find  a little info on gene traits. If anyone else can find anything on this please share it with us. Here is what I found:
 
 

What causes lupus?

Lupus is an autoimmune disorder, which means the body's immune system attacks its own healthy cells and tissues.

 

Lupus is considered to be a multifactorial condition. Multifactorial inheritance means that "many factors" are involved in causing a health problem. The factors are usually both genetic and environmental, where a combination of genes from both parents, in addition to unknown environmental factors, produce the trait or condition. Often one gender (either males or females) is affected more frequently than the other in multifactorial traits. Multifactorial traits do recur in families because they are partly caused by genes. Females are affected with lupus three to 10 times more often than males.

 

A group of genes on chromosome 6 codes for the HLA antigens which play a major role in susceptibility and resistance to disease. Specific HLA antigens influence the development of many common disorders, many that are autoimmune related and are inherited as multifactorial traits. When a person has the specific HLA antigen type associated with the disease, they may have a genetic susceptibility to have the condition and be more apt to develop it. The HLA antigen associated with lupus is called DR2 and DR3. It is important to understand that a person without these antigens may also develop lupus, so that HLA antigen testing is not diagnostic or accurate for prediction of the condition.


 Co-Mod: Lupus Forum
 Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Sensory Polyneuropathy
Meds:Arava,plavix,aspirin,protonix,gabitril,zanaflex,xanax,
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JOB 5:18 For he wounds, but he also binds up; he injures, but his hands also heal.


NanaBee
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   Posted 3/16/2007 10:54 AM (GMT -7)   

I don't know what type of blood my parents had but I am O+ too.  Interesting topic!!

 

Mary Ann :-)


 
**Diagnosed MCTD(doctor now says it is Lupus),Fibromyalgia,Raynaud's June 2005
**Sleep Apnea - February 2006
**Congenital Heart condition-Pulmonary stenosis, High blood pressure, IBS, degenerative disc disease, vertigo
 "No matter what happens, God is in control.  He is God, I am not, what a relief!"


jhmom
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   Posted 3/16/2007 11:12 AM (GMT -7)   
I don't know what blood type my parents have, will have to ask my mom but I am O+ too!!!!
Stacie

Trust in the Lord with all thine heart, and lean not unto thine own understanding

~ Proverbs 3:5 ~

DX: Hashimoto's 1999, Celiac 2003, Raynaud's 2004, Costochondritis 2004, Lupus 2005 and Sjogrens 2006

Imuran, Plaquenil, Flexeril, Sulindac, Levoxyl, Folic Acid and magic mouthwash (as needed)


Lynnwood
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Date Joined May 2005
Total Posts : 7018
   Posted 3/16/2007 11:16 AM (GMT -7)   
Are Rh+ and Rh- factors the same as the +/- indications on the blood type? I thought they were different, I found this article that might explain it, but don't have time to read it right now. Ya'll figure it out for me, ok? tongue


www.biology.arizona.edu/human_bio/problem_sets/blood_types/rh_factor.html

Follow the link at the bottom to blood types, it gives a calculator so if you know both parents or one parent/one child, you can figure out the 3rd persons possible types!

 

Lynnwood, Co-Moderator: Lupus Forum
SLE(’00), Sjogren's Syndrome, Raynaud's Syndrome ,SAD, Depression, Herpes Simplex 1
Piroxicam, Plaquenil, Cellcept, Prednisone, Xanax, Trazodone, Fosamax, Wellbrutrin SR, Valtrex
Links: DIAGNOSING LUPUS (4 of 11), LUPUS INFORMATION & LUPUS RESOURCES & Donate to HealingWell


mom46
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   Posted 3/16/2007 11:52 AM (GMT -7)   

Lynn,

  Hmmm...that is odd! When you click on the tabs to calculate it doesn't give the blood type RH to choose from, only O's, A's and B's.

  RH blood is suppose to be a rare blood type. My mom had Rh neg as well as my two oldest brothers and me and one brother are O+. My next to the oldest brother was actually given a complete blood transfusion when he was born because of the blood type, so I guess I really don't know what type he is now. I will have to ask him when I talk to him again, but hardly ever talk to him.

  Ok, I just called my dad..lol. I had to make sure I knew what I was talking about. My mom had rh neg, my oldest brother does have rh neg and the next to the oldest had the blood transfusion at birth, but he didn't know what type that brother was given.

  I don't understand why Rh- and Rh+ aren't reconized as a blood type. I will have to ask at work about this when I go in today. confused  

                                                                 Babs



 Co-Mod: Lupus Forum
 Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Sensory Polyneuropathy
Meds:Arava,plavix,aspirin,protonix,gabitril,zanaflex,xanax,
mirapex,advair,foxamax,donnatal,folic acid.
 
JOB 5:18 For he wounds, but he also binds up; he injures, but his hands also heal.

Post Edited (mom46) : 3/16/2007 1:00:09 PM (GMT-6)


okie
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   Posted 3/16/2007 12:16 PM (GMT -7)   
When my first son was born he was A pos. so they gave me a shot. when my second son was born he was o neg. I am RH neg also so this time I didn't have to have a shot. I know that before the RH factor was known about many kids were born and died shortly after because of the blood mixing together. My shot was to kill off my immune system after the first child so I didn't have a miscarriage if I had a second child. I've heard this question asked before rein regards to lupus having your immune system attacking an RH pos. child if the mom was RH neg. I was wondering if it possibly to send your body haywire because it could cause miscarriages because of the differences in the blood type. It actually attacks an unborn child as an unknown alien to your body. I have done some study on this with my b neg blood. My mom also had 3 miscarriages.

I would love to know if this has anything to do with the immune going haywire

thanks for asking
love ya
carol
God Bless
Carol
 
. Diagnosed Lupus Nov 06. xanax X3,triam high BP, percocet, inhalers,COPD. oxygen Plaquanil400mil, Pred. as needed. effexor.


mom46
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Date Joined Dec 2004
Total Posts : 8198
   Posted 3/16/2007 12:36 PM (GMT -7)   

 I found this that shows all the blood types from the American Red Cross. Now this has me wondering if my mom and brothers are AB neg and they just called it Rh neg.

  

What's Your Blood Type?
  • O Rh-positive: 38 percent
  • O Rh-negative: 7 percent
  • A Rh-positive: 34 percent
  • A Rh-negative: 6 percent
  • B Rh-positive: 9 percent
  • B Rh-negative: 2 percent
  • AB Rh-positive: 3 percent
  • AB Rh-negative: 1 percent

 


 Co-Mod: Lupus Forum
 Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Sensory Polyneuropathy
Meds:Arava,plavix,aspirin,protonix,gabitril,zanaflex,xanax,
mirapex,advair,foxamax,donnatal,folic acid.
 
JOB 5:18 For he wounds, but he also binds up; he injures, but his hands also heal.


okie
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Date Joined Dec 2006
Total Posts : 2818
   Posted 3/16/2007 12:45 PM (GMT -7)   
Yes hun, I'm Bneg and my son is o neg. and they are called RH neg. In other words you don't have the rh factor in your genes. 85 percent of the population have the rh factor which would be rh possitive.
 
If your mom is AB- than in short it would be called rh neg. but just like with any transfusion the possess would still have to match which blood type not just the  plus or minus. The only universal blood type that anyone can use is o neg. that type is in high demand in hospitals. I don't know why that is though.
hug


God Bless
Carol
 
. Diagnosed Lupus Nov 06. xanax X3,triam high BP, percocet, inhalers,COPD. oxygen Plaquanil400mil, Pred. as needed. effexor.

Post Edited (okie) : 3/16/2007 1:55:40 PM (GMT-6)


mom46
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Date Joined Dec 2004
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   Posted 3/16/2007 1:19 PM (GMT -7)   

Tks Carol,

   I really don't know what their blood type is other than Rh neg...I never heard anyone say A, B, O or AB, just the Rh neg. I just saw that the most rare was Ab neg...lol.

  Ok, I'm getting a good lesson in Blood Types 101 and it's very interesting...LOL  Also confusing..... eyes .

                                                                           Babs


 Co-Mod: Lupus Forum
 Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Sensory Polyneuropathy
Meds:Arava,plavix,aspirin,protonix,gabitril,zanaflex,xanax,
mirapex,advair,foxamax,donnatal,folic acid.
 
JOB 5:18 For he wounds, but he also binds up; he injures, but his hands also heal.


Lynnwood
Forum Moderator


Date Joined May 2005
Total Posts : 7018
   Posted 3/16/2007 1:22 PM (GMT -7)   
O- is known as "the universal donor" as we can give blood to anyone of any blood/rh type. And there are only 7% of us!!!!

 

Lynnwood, Co-Moderator: Lupus Forum
SLE(’00), Sjogren's Syndrome, Raynaud's Syndrome ,SAD, Depression, Herpes Simplex 1
Piroxicam, Plaquenil, Cellcept, Prednisone, Xanax, Trazodone, Fosamax, Wellbrutrin SR, Valtrex
Links: DIAGNOSING LUPUS (4 of 11), LUPUS INFORMATION & LUPUS RESOURCES & Donate to HealingWell


CaptSue
Regular Member


Date Joined Jan 2007
Total Posts : 279
   Posted 3/16/2007 1:40 PM (GMT -7)   
Hi all,

I'm going to take my shot at explaining what I think is going on. Please bear with me. The are "things" one can have in their blood (ok, there has to be a real term for thing but it would not be helpful). If you have the A whatever they label your blood type with an A (or a B for the B whatever) so that AB means you have both, A means only A, B means only B and O means your blood has neither. There is also an Rh factor. You either have this "thing" in your blood (denoted with a +, you'd think with the other scheme they would call it R but I think we're doing an apples and oranges on whatever these "things" are and Rh is a different thing than A, B) or you don't (denoted with a - ). So, AB+ means you have all of them and O- means you have none of them. Your body gets unhappy with a transfusion that contains "things" you don't have but is fine with blood containing things you don't have. So O- has none and everybody can take O- in a transfusion (so that is the universal donor) and AB+ has three things so AB+ blood can only be transfused to an AB+ person.

Ok, so an (any blood type A, B, AB or O doesn't matter) Rh- mother carrying an Rh+ baby will try to attack the baby because the babys' blood contains the, foreign to the Mother, Rh + factor. In the "old" days after such a birth if the Mother again carried an Rh+ baby, the Mothers immune system would figure out that this was an old invader and would attack the new baby, causing all sorts of problems for the new baby (although I believe the first Rh+ baby carried by an Rh- Mother is ok).

Too long. But I actually think I have the correct idea.

Stay Strong,
Sue
Diagnosis: Mixed connective tissue disease (systemic lupus, scleroderma, polymyositis), Raynauds phenomena (both diagnosed in 2006)

Meds: prednisone (5.0 mg and tapering), Imuran (2X50mg), Prilosec(2x20mg), Prozac (20mg)


CaptSue
Regular Member


Date Joined Jan 2007
Total Posts : 279
   Posted 3/16/2007 1:43 PM (GMT -7)   
EnigmaGirl,

Our posts crossed. I think we both have it right only yours was shorter!

*hugs*
Sue
Diagnosis: Mixed connective tissue disease (systemic lupus, scleroderma, polymyositis), Raynauds phenomena (both diagnosed in 2006)

Meds: prednisone (5.0 mg and tapering), Imuran (2X50mg), Prilosec(2x20mg), Prozac (20mg)


ericsmom
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Date Joined Jan 2007
Total Posts : 1042
   Posted 3/16/2007 1:47 PM (GMT -7)   
Hi..
 
I am A+, my oldest sis is rh-, and my first born son is 0- and has been donating to the redcross for years because of it's rarity...hmmmm that is all I know..the rest of my son's are A+
A/Fib, diagnosed Aug, 1997, R/A diagnosed in Sept. 1998, Pericarditis and Lupus in Dec, 2003, Diabetes, diagnosed march, 2004
 
sotalol, digoxin, coumidin, plaquenil, prednisone, metformin, diamacron, wellbutrin,fenofibrate


okie
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Date Joined Dec 2006
Total Posts : 2818
   Posted 3/16/2007 2:00 PM (GMT -7)   
I was just wondering if there have been any tests linking auto immune disease to this because for the most part women have lupus more than men by a considerable margain and it seems to be more of a problem just before your period. when your hormones are out of wack. I have goggled it and can't find anything. Just a thought. It may be nothing. I'm no doctor but it seems like they would have at least explored the possibility.


hugs
carol
God Bless
Carol
 
. Diagnosed Lupus Nov 06. xanax X3,triam high BP, percocet, inhalers,COPD. oxygen Plaquanil400mil, Pred. as needed. effexor.


mom46
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Date Joined Dec 2004
Total Posts : 8198
   Posted 3/16/2007 6:16 PM (GMT -7)   

Tks Enigma and Sue for explaining this better. I have 3 older brothers, none of them have any type of immune disease, just me. It's so strange how that works. The ones in my family that do have immune disorders are on my dad's side, but I did have a distant cousin on my moms side that had MS.

                                                        Tks again, Babs


 Co-Mod: Lupus Forum
 Lupus,RLS,RA,Asthma,Fibro,Sjogren's,Raynaud's,Divertic, Stroke,Atherosclerosis,Seizures,Sensory Polyneuropathy
Meds:Arava,plavix,aspirin,protonix,gabitril,zanaflex,xanax,
mirapex,advair,foxamax,donnatal,folic acid.
 
JOB 5:18 For he wounds, but he also binds up; he injures, but his hands also heal.


ericsmom
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Date Joined Jan 2007
Total Posts : 1042
   Posted 3/17/2007 5:50 AM (GMT -7)   
Just wanted to add, that my other sibs dont have the rh factor or O, and I also have a twin brother who is healthy, maybe because we are fraternal twins I dont know
 
Diane
A/Fib, diagnosed Aug, 1997, R/A diagnosed in Sept. 1998, Pericarditis and Lupus in Dec, 2003, Diabetes, diagnosed march, 2004
 
sotalol, digoxin, coumidin, plaquenil, prednisone, metformin, diamacron, wellbutrin,fenofibrate

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