I don't have an answer for you about West Nile, but for those of us taking plaquenil, at least we probably won't get malaria :) You are right that for those of us who are taking any immunosuppressant drugs like mtx, perhaps we are more susceptible to weird things like West Nile virus. For me, personally, though--I think the risk is so minimal that it's not a major issue with me. I'm more concerned about the regular flu, especially since I didn't get a flu shot this year.
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