Rheumatoid factor positive then negative

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cured4real?
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   Posted 7/17/2007 1:44 PM (GMT -7)   
I was tested for Rheumatoid factor and it came out positive a few years ago and then I was retested a month or so later and it was negative.  My primary said this means I don't have RA. But can it go positive and then negative if you have RA or is it always positive?  I forgot to bring this up with the rheumy, brain not working well these days.
Love, Marji
--Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less in human beings of whom they know nothing.--Voltaire (1694-1778)
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dbab
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   Posted 7/17/2007 1:58 PM (GMT -7)   
I don't know much about it going positive to negative or the other way. I'm sure its possible because many tests do, especially with Lupus type of tests. I think I read though that only about 70% of people with RA test positive for the rheumatoid factor so I'm not sure how your doc is ruling it out completely especially since it was positive at one point. I would definitely tell your rheumy the next time you see him, he would have more experience with this test than the primary. Good luck.

Take Care
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hippimom2
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   Posted 7/17/2007 4:03 PM (GMT -7)   
marji, I had a similar experience. A few years ago my rheumatoid factor was just barely positive (one point over), so the rheumy didn't pay much attention to it anyway. Then about 6 months later it was re-tested during a flare and was negative. I really didn't ask about it since no one paid much attention to the first one anyway. I agree with Des that I'm guessing a lot of these labs fluctuate. Definitely ask about again when you see your rheumy. Of course none of this can be easy or clear cut.

Take care
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