Lupus related to Crohns?

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Jenny S.
Regular Member

Date Joined Oct 2007
Total Posts : 80
   Posted 10/19/2007 6:20 PM (GMT -6)   

My mother has Crohns – another autoimmune disease.  Just wondering if anyone else has had this hereditary link as well?  This is the only connection the docs can link to my Lupus diagnosis as far as family history.   



I have Lupus ... Lupus doesn't have me. :)
Dx:  Raynaud's (2000) · Pericardial Effusion (2001) · Lupus (2001)
Rx:  Pletal 100 mg · Norvasc 5-10 mg (as needed) · Prednisone 5-10 mg (as needed) · Plaquenil 400 mg · Prozac 20 mg (for anxiety)
O-T-C meds:  Adult Aspril 325 mg · Acid Controller (Famotidine) 10 mg · Allergy Relief (Loratadine) 10 mg
Supplements:  DHEA 100 mg ·  Potassium 595 mg  

Post Edited (Jenny S.) : 10/19/2007 5:28:44 PM (GMT-6)

Barbara Lee
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Date Joined Sep 2003
Total Posts : 2889
   Posted 10/19/2007 6:38 PM (GMT -6)   
Hi Jenny:

The exact reason why a person gets lupus it's know. They say that people who have lupus may have an additional auto immune disease like Crohns. Is it hereditary from your mom is truly unknown. Did you get the lupus cause she has crohns disease I don't know. I know for awhile when I had my colon removed and continued to have "GI" issues they thought I may have crohns disease. Of course I don't have crohns but my doctors were all saying it's common to have more than one AI disease at a time.

Take care,
dx fibro, SLE, glaucoma, cateracts, bells palsy, depression, migraine headaches, gastreopaersis, chronic anemia, RA,MDS (Blood Cancer). Tons of meds.

Veteran Member

Date Joined Jul 2007
Total Posts : 1048
   Posted 10/20/2007 2:10 PM (GMT -6)   
My younger brother has Crohn's and had Ulcerative Colitis (total colectomy). My father's side has TONS of AI diseases; cancer, RA, diabetes, MS, Lupus, Crohns/ name it! My former supervisor has lupus and Crohn's. There definitely seems to be a connection. Judy

Veteran Member

Date Joined Aug 2007
Total Posts : 4389
   Posted 10/20/2007 3:13 PM (GMT -6)   
Yes, there is a common genetic link between Crohn's and Lupus and many other autoimmune diseases. Those who are diagnosed with both need to make sure that their gastrointestinal symptoms are not from Gastroenteric can be difficult to tell them apart.

Take care,
Gluten & Sulfite Sensitivity, Multiple Food & Inhalant Allergies, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD (Lupus?), Osteoporosis, Anemia, malabsorption/malnutrition, etc.
Meds:  Pulmicort, Claritin, Injectable Vitamin B12, Herbs, Nutritional Supplements, Essential Oils, Homeopathy.

Regular Member

Date Joined Aug 2007
Total Posts : 31
   Posted 10/21/2007 11:36 AM (GMT -6)   


I have Severe Systemic Lupus and Sjogrens. My brother was diagnosed seven years prior to me with Chrohn's disease. We were both twenty-nine. He manages it but has not had to have major surgery thank goodness. I believe there is a connection.



Regular Member

Date Joined Jul 2007
Total Posts : 261
   Posted 10/23/2007 3:30 PM (GMT -6)   
Hi, Jenny. My dad has Crohn's disease and I have both SLE and Sjogren's. From all the reading I've done, I think they know there is some genetic link but have not exactly pin-pointed it yet. I've noticed a lot of people that have one kind of AI disease, that other types of AI disease run in their families.
Always looking for the silver lining, Sharen

SLE '06, Sjogren's '06, Traumatic Head Injury '94
Prednisone 9mg and tapering, Caltrate 1200mg, Multi-vitamin, Prevacid 30 mg, Actonel 35mg, DocQLace 200mg, Flax Seed (milled) 2Tbsp

Regular Member

Date Joined Oct 2007
Total Posts : 33
   Posted 10/23/2007 3:46 PM (GMT -6)   
To answer the question, in a previous note my daughter has lupus,  I have had reaccurant clotting disorder Thrombotic Thrombocytopenia purpura ( my daughter has APS, a clotting disorder) I also have Crohns.  I have a postive ANA with speckled patterm, but not so symptomatic as my daughter or diagnosed.  I have a Aunt with Ehlers Danlos a rare connective tissure disease.  I also had a aunt with M.S.
So it really makes you think there is a connection in between auto-ammune diseases.

Regular Member

Date Joined Oct 2005
Total Posts : 251
   Posted 10/24/2007 9:14 AM (GMT -6)   
My dad has Crohn's so I'm guessing that is where my AI genetic link comes one on my mother's side has AI problems.
SLE diagnosis 10/05 now changed to RA 3/06, Endometriosis 5/05, PCOS 1990
Meds: Metformin ER 1500mg (PCOS); Loestrin BCPs (Endo); Methotrexate 15mg (RA); Metanx 5mg (RA); Orencia 750mgs (RA); Lunesta 2mg (as needed); Prevacid

New Member

Date Joined Apr 2007
Total Posts : 14
   Posted 10/29/2007 8:08 PM (GMT -6)   
Im 41 yrs old and was diagnosed with Lupus 4 yrs ago. I have a 12 yr old daughter that was diagnosed with Chrons Disease 1 1/2 yr ago. I think that their is a definate Link between the two.
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