Glucophage and gi problems

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cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/19/2007 10:12 PM (GMT -7)   
Well, it may be my glucophage ER is the culprit for my gi issues.  I must take it for my liver problem.  I think I need to be very careful how I take it.  The hepatologist told me that he would be surprised if I didn't have gi problems taking glucophage.  I guess its a common side effect.  I still have the intermittent pancreas problem which I can take enzymes for and the IBS, but maybe the irritation might have been from taking the glucophage and not eating beforehand or taking it with milk or maalox even.  I ran out of the ER and had to take the regular stuff and it made me so sick and so I'm thinking that it might have caused the irritation once, and then it just never got better.  At least that's what I'm hoping.  Any ideas on how to buffer my stomach and small intestine so when I take it it is't so bad?  Thanks in advance for any ideas.  I usually eat a small amount of oatmeal or grits lately in the morning because it is the only thing I can keep down and a banana. 

Love, Marji
--Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less in human beings of whom they know nothing.--Voltaire (1694-1778)
Ills--Sjogrens-Lupus-like AI Disease, Hashis, Vitiligo, spinal stenosis/fusion with plate, salivary/lymphectomies, Diabetes, NAFLD, COPD, RLS, neuropathy, trigonitis, hystero, diffuse brain atrophy
Meds--Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, Estradiol patch, Prosed, Klonopin, Soma, Ultram, Vicodin, Restasis, Albuterol,steroid injections, Protopic & Triamcinolone Acetonide ointments


PattyLatty
Veteran Member


Date Joined Mar 2006
Total Posts : 2570
   Posted 10/19/2007 10:38 PM (GMT -7)   
What has your doctor advised, Marji? If I were to guess, and this is a guess only, I'd think that taking acifex would be a good way to fend off any stomach issues. I take it from time to time when my stomach is acidic and giving me fits.
Lupus, Sjogren's, osteoarthritis, fibro, renauds, restless leg, hiatal hernia, double vision, migraines.
cellcept, neurontin, prednisone, plaquenil, synthroid, triamterene, tramadol, actonel, tri-est, imitrex, cymbalta, multivitamin, calcium w vit D, fish oil, aspirin


AlwaysRosie
Veteran Member


Date Joined Jan 2005
Total Posts : 8616
   Posted 10/20/2007 1:59 AM (GMT -7)   
Hi Marji,

You might pop over to the diabetes forum and post there. You'll likely get more answers. I didn't realize that those meds were hard on your stomach skull sorry you are having such trouble.

Blessings!

In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Hashimotos, Inflammatory Bowel, Inflammatory Arthritis

Clickable Links:  Lupus Resources    Lupous.Org   Lupus Criteria (4 of 11)   Lupus Chapter Locator


Trying2BFree
Regular Member


Date Joined Oct 2005
Total Posts : 251
   Posted 10/20/2007 6:10 AM (GMT -7)   
I take it (Metformin is the generic) and have for almost 5 years. I've never had any problems with it, but I think it's more common to get gi effects than to NOT get them. I just got lucky. LOL

I take 750mgs in the morning right after breakfast with a glass of water. Then I take the other 750mgs after dinner. I've always taken it with food and water, and occasionally with milk after a meal. Definitely eat something before you take it. Good luck!
Jeannie 
SLE diagnosis 10/05 now changed to RA 3/06, Endometriosis 5/05, PCOS 1990
Meds: Metformin ER 1500mg (PCOS); Loestrin BCPs (Endo); Methotrexate 15mg (RA); Metanx 5mg (RA); Orencia 750mgs (RA); Lunesta 2mg (as needed); Prevacid


cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/20/2007 9:36 PM (GMT -7)   
I usually eat immediately after, so it all should mix up but who knows. Thanks Jeannie, Rosie, and Patty. I just put in new light bulbs and my tan has greatly faded since I can't go outside in the sun anymore and I looked in the mirror and I'm really jaundiced, so that's likely the problem. I didn't realize how bad I was since my tan usually hides it. My eyeballs and under tongue are bad and hands are pure yellow. Oh well, see the new endo on Tuesday and will push for pred. It helps everything.
Love, Marji
--Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less in human beings of whom they know nothing.--Voltaire (1694-1778)
Ills--Sjogrens-Lupus-like AI Disease, Hashis, Vitiligo, spinal stenosis/fusion with plate, salivary/lymphectomies, Diabetes, NAFLD, COPD, RLS, neuropathy, trigonitis, hystero, diffuse brain atrophy
Meds--Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, Estradiol patch, Prosed, Klonopin, Soma, Ultram, Vicodin, Restasis, Albuterol,steroid injections, Protopic & Triamcinolone Acetonide ointments


AlwaysRosie
Veteran Member


Date Joined Jan 2005
Total Posts : 8616
   Posted 10/21/2007 3:37 AM (GMT -7)   
Uh oh Marji . . . that yellow doesn't sound good. Does the endo deal with your liver issues?? I hope the pred is all you need . . . that really sounds bad. Keep us posted sis.

Blessings!

In His Grip

AlwaysRosie           "We can't control the waves, but we can learn how to surf!!"

Psalms 139

Co-Moderator - Lupus Forum

UCTD, Hashimotos, Inflammatory Bowel, Inflammatory Arthritis

Clickable Links:  Lupus Resources    Lupous.Org   Lupus Criteria (4 of 11)   Lupus Chapter Locator


cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/21/2007 10:01 AM (GMT -7)   
Thanks rosie. I don't want to go into the other gi symptoms! Nope this is first visit with new endo. Could be recent increase in pain meds and whatever illness I'm feeling, along with my UT meds. My hepatologist said that when you get to be taking more than three or five meds daily, it get nearly impossible not to have some gi and liver problems. I look much better today but will request bloodwork. I guess sometimes stuff just backs up or goes high in your system. I wonder if they have ever tested me for Primary Billiary Cirrhosis? People here have been finding out they have it, it seems like a no brainer, huh?
Love, Marji
--Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less in human beings of whom they know nothing.--Voltaire (1694-1778)
Ills--Sjogrens-Lupus-like AI Disease, Hashis, Vitiligo, spinal stenosis/fusion with plate, salivary/lymphectomies, Diabetes, NAFLD, COPD, RLS, neuropathy, trigonitis, hystero, diffuse brain atrophy
Meds--Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, Estradiol patch, Prosed, Klonopin, Soma, Ultram, Vicodin, Restasis, Albuterol,steroid injections, Protopic & Triamcinolone Acetonide ointments


Snickerdoodle
Regular Member


Date Joined Aug 2006
Total Posts : 142
   Posted 10/21/2007 11:49 AM (GMT -7)   
Hi Marji,
I took glucophage for a while for poly cystic ovarian syndrome (another misdiagnosis) anyhow I noticed that ANYTHING greasy or carb loaded gave gi upset. Forget McDonalds. That was one good thing about it, it made me eat healthy. The glucophage takes carbs out of your small intestine, thats why it works so good for diabetics. So try altering your diet for a while until your system gets used to it. I know it took about 2 months for me to feel back to normal. Also, look at www.askapatient.com. Its a great site for anyone trying new meds. I go there everytime I get a new script. It gives you their diagnosis, and their side effects and thier rating of the drug.
good luck!
Melissa
Dx: UCTD,Raynaud's,iron deficientcy anemia,proteinuria
Rx: Multi-rec folic 500, Mobic 15 mg, Plaquenil 400mg


cured4real?
Veteran Member


Date Joined Dec 2005
Total Posts : 1944
   Posted 10/21/2007 7:18 PM (GMT -7)   
Thanks so much, Melissa.  I've actually been doing that because they suspected celiac disease.  I can handle a small amount of grits or oatmeal in the morning, which helps with my nausea and gets my sugar up some, but not during the day.  I usually have soup for lunch and meat and vegetables for dinner.  Salad has not been a big winner with me.  Cottage cheese seems ok.  I'm just a mess gi wise.  I don't know why the oatmeal doesn't bother me like potatoes and bread do, guess because of the fiber and the colloidal part of it.  Grits have been ok too, which really surprised me.  I notice that sometimes when my food is not digested the glucophage tablet comes out whole and undigested. Prednisone has helped the most, maybe help me get it healed up.  I don't want to give up my oatmeal or grits, though I prefer oatmeal, in the morning.  I hope I don't have to.  I'm not well enough in the morning to make myself anything any better and even diabetic meal replacements have been making me really sick, the sweeteners maybe.  I will check out that site.  There is no way I can quit the glucophage because of my liver, but I will have to find a way to take it better, maybe eat first instead of just after so the pill is not lying on my intestine.  Thanks for the site info.  I will have to check it out.  How are you doing anyway?  I haven't heard from you for a while...
Love, Marji
--Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less in human beings of whom they know nothing.--Voltaire (1694-1778)
Ills--Sjogrens-Lupus-like AI Disease, Hashis, Vitiligo, spinal stenosis/fusion with plate, salivary/lymphectomies, Diabetes, NAFLD, COPD, RLS, neuropathy, trigonitis, hystero, diffuse brain atrophy
Meds--Plaquenil, Evoxac, Metformin, Synthroid, HCTZ, Estradiol patch, Prosed, Klonopin, Soma, Ultram, Vicodin, Restasis, Albuterol,steroid injections, Protopic & Triamcinolone Acetonide ointments

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