IV vs. Oral? Opinions appreciated

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needshelp
Regular Member


Date Joined Aug 2008
Total Posts : 225
   Posted 10/5/2008 12:36 PM (GMT -6)   
Hi again,
 
As I've previously posted, I am positive for Lyme (IgeneX) but have not been tested for co-infections (yet).  My first visit to the LLMD is coming up in a couple weeks.  I've been quite ill but really NEED to stay as functional if possible (so I can work and have health insurance).  I was wondering what the concensus is on IV vs. oral antibiotics.  What are the pros and cons?  Will I see a quicker improvement with IV vs. oral?  etc. 
 
Thanks very much.
Brad

jginkc
Veteran Member


Date Joined Jan 2008
Total Posts : 692
   Posted 10/5/2008 12:58 PM (GMT -6)   
I think a lot of depends on how long you have been sick and what your symptoms are. My understanding from all I have read is that if you have CNS involvement, like seen in a SPECT scan, that IV's are a better option. Otherwise orals are ok.

Some people on here saw remarkable progress on IV's while others saw slow improvement.

Keeping your job is important -I am in the same boat. Very hard to work when you don't feel well.
Month 18 of Lyme and Bartonella
On Zhang, doing much better, but not there yet!

90% functional, feel about 85% of my former self.


Educate yourself
Regular Member


Date Joined Jun 2012
Total Posts : 23
   Posted 7/31/2012 5:50 PM (GMT -6)   
Just bringing up an interesting old post.

Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 33646
   Posted 8/1/2012 4:12 PM (GMT -6)   
Since that time, thinking on this has changed. Some people have troubles with absorption, in which case IV treatment would be necessary, but otherwise it's pretty much what the doctor is most comfortable with, not how long you've been infected. The goal is to be able to get very high concentrations of the abx in the blood, and that can usually be done easily with orals, which is less costly, less time consuming, and would allow someone to be able to continue on with work much easier.
Treating with Acupuncture, Traditional & Modern Chinese Medicine & Western Herbs. Before tx, I had all but 20 of the symptoms on the "Master Symptom List"

"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP

Questions about what I've posted or just have questions? Please email me!!! Click on the blue envelope under my screen name!

devia
New Member


Date Joined Jul 2012
Total Posts : 15
   Posted 8/2/2012 4:49 AM (GMT -6)   
That is all true however if you have brain involvement you need iv abx because oral abx wont cross the blood brain barrior but iv's will

achievinggrace
Forum Moderator


Date Joined Nov 2009
Total Posts : 3266
   Posted 8/2/2012 6:07 AM (GMT -6)   
The macrolid class of antibiotics in any form cross the blood brain barrier.

A lot of doctors start you on oral antibiotics to see how you progress and only go to IV's when your healing stalls out.

It would be a good idea to explain to your doctor that you need to remain functional during treatment. That would probably call for a "low and slow" approach, which is favored by many LLMD's as it produces the best long-term success.

Wishing you well
Co-Moderator Lyme Disease Forum

Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 33646
   Posted 8/2/2012 6:18 AM (GMT -6)   
Hi Devia,
I'm sorry, but it seems that you were given some wrong information, or maybe you misunderstood. Actually there are several abx that do cross the blood-brain barrier, as can be seen in these articles:

www.utmb.edu/otoref/grnds/Microbiology-2004-0218/Microbiology-2004-0211.htm

www.cpnhelp.org/antibiotics_useful_agains

www.anapsid.org/lyme/matthewgoss/drugs.html
Treating with Acupuncture, Traditional & Modern Chinese Medicine & Western Herbs. Before tx, I had all but 20 of the symptoms on the "Master Symptom List"

"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP

Questions about what I've posted or just have questions? Please email me!!! Click on the blue envelope under my screen name!
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