Of all the possible combos i've done in the past. My favorite is Bactrim combined with Biaxin and doxy. Or Roxithromycin/Bactrim/doxy. BActrim by itself wasn't too special and doxy by itself was just slow progress.
Bactrim does produce a more emotional depressed state of mind but i honestly think it is mainly due to a herx. Zithromax can do the same but not like biaxin. Maybe try zithromax with bactrim first and see how you do, then swap it for biaxin later on. I also did Roxithromycin which is a macrolide similar to biaxin. I had just about the same results with roxy versus biaxin.
The reason why I orginally adopted this protocol is because chlamydia pneumoniae is treated in this manner. The symptom for chlamydia pneumoniae are similar to lyme, bart etc. So i've taken the treat everything approach and that has proven effective for me.
The Chlamydia pneumoniae protocol involves low doses of each taken for 2-3 years. And this isn't the sexually transmitted chlamydia. I didn't see anything wrong with this protocol and it appeared to mirror many lyme protocols. I slightly modified it and took N-acetyl cysteine from time to time. In my case, i didn't see too much from NAC.
1. Tetra class abx (doxy, tetra etc)
2. Macrolide class abx(zithromax, biaxin, roxithromycin)
3. Bactrim, rifampin or mycobutin (low dose)
4. Weekly flagyl pulses every one to two months.
5. N-acetyl cysteine
Example day: 200mg doxy, 500mg biaxin, 2-4 bactrim regular, N-acetyl cysteine.
Kind of a long story but just showing you what brought me to test out bactrim with a macrolide and tetra. If you have a babesia componant than this would have to be modified even further. If trying to treat babs, bart and lyme. Then i'd recommend dropping the tetra class for mepron, malarone or artmesia. So if trying to get all of the dreaded 3 plus more, it could go like this. Bactrim, Biaxin, Mepron or even Zithromax, Mepron, Bactrim, Artmesia.
Post Edited (phsinvent) : 10/8/2008 11:00:25 AM (GMT-6)