Hi Buffster, welcome to the board!
If you would like help interpreting the Western Blot, let us know. You can post your brother's results.
Below is a Lyme symptom list. You can have any combination of symptoms.
It is very important to see a knowledgeable doctor. Besides Lyme, ticks can also transmit several co-infections including Babesiosis, two types of Ehrlichiosis (HME & HGE), Bartonella, and Mycoplasma. Many people who have Lyme are co-infected. It may affect treatment choice and progress. It is important to be tested for these by a Lyme reputable lab such as IgeneX in Palo Alto, CA. Has your brother been tested for these?
The closest doctors I know of are in the UK. If you would like the information, you can email me at email@example.com You may be able to get doctor recommendations at EuroLyme Support forum www.groups.yahoo.com/group/EuroLyme/
Be aware of the Jarisch-Herxheimer Reaction (herx). Often, when people who have Lyme take antibiotics their symptoms get worse or they get new ones. When the antibiotics kill the bacteria, toxins are released making them feel worse. It can be scary when it happens, but it is a sign the antibiotics are working. Although this reaction can vary individually, many people experience this at the beginning of treatment and every three to four weeks.
During treatment, it is good for your brother to document his symptoms daily. One way to do this is to list the three main symptoms he has each day with a numerical rating of their severity from 1-10. Over time when he reviews this, he can see when his herxes occur and how he is responding to the meds.
It is also important to learn as much as possible. I recommend reading Dr. Joseph Burrascano's 2005 Diagnostic Hints and Treatment Guidelines For Lyme and Other Tick Borne Illnesses at http://www.ilads.org/burrascano_0905.html He is one of the top Lyme doctors in the country, and many Lyme doctors follow his protocols. He also lists diet, supplement, and exercise recommendations. I also recommend the books "Everything You Need To Know about Lyme Disease Second Edition" by Karen Vanderhoof-Forschner and "The Lyme Disease Solution" by Kenneth B. Singelton MD.
I hope your brother can start treatment soon. He is lucky to have your support.
Thank you so much for your reply and all the helpful information. I have printed the article by Dr. Burrascano and I have requested another test kit from Igenex to test for those futher infections.
His results were
23-25 kDa. IND
32 kDa. IND
39 kDa. +
41 kDa. +
All the rest were negative. From what I know my brothers symptoms have been foot drop (severe), fatique, stomach problems, sore throat, light sensitivity, worse symptoms after alcohol, muscle pain and cramps.
He had various tests done here in Ireland and was diagnosed with als/mnd. They didn't seem interested in testing for Lyme even though he has what looks like a bite on his leg (a small kind of purple lump right on the muscle that has gone weak and caused his foot drop) and after we researched and saw that Lyme symptoms were very similar to als/mnd we decided to get him tested ourselves. We're all very excited that this result is positive but are afraid to get our hopes up until it can be confirmed as Lyme (I know Lyme is awful but compared to als/mnd...)
I will email you personally for the details of the UK doctor.
Thanks so much again for your help,