I started that protocol after my antibiotics. But after 45 days I quit, because my symptoms came back... I can't tell you if it worked or not. I might have had a herx or just not working. But for me it was a sign that I still had Lyme. I called my doc and I'm back on regular treatment now.
EM rash oct. 24 2007, 10-30-08: doxy 100 mg. bid for three weeks. Felt better, but symptoms slowly got back and much worse
2-21-08 until 4-23-08: doxy 100 mg. bid (described by family doctor)
4-24-08: start doxy 200 mg. bid and Biaxin XL 1000 mg once a day (seeing an Infectious Disease Doctor)
8-8-08 until 8-21-08: adding Flagyl 500 mg. bid
8-21-08: off all ABX
9-17-08: doing herbs but symptoms slowly reappeared,so started Biaxin 500 mg. bid on 9-17-08
11-12-08: off abx, start Diflucan