Considering one of the main places the lyme bacteria goes is your brain, it seems reasonable anxiety could be a "first" symptom. My "first" symptoms was headaches. And I spent months with docs treating me for headaches.
If your "myriad of symptoms" equals lyme then you are like most if not all of the rest of us. You even know you got bit by a tick and you live and play in the woods of africa and maryland.
Part of lyme disease is constantly wondering if you have it, I think. Pursue it with passion and you will beat it.