Hi springsjean. I have had HGE. From what I understand, Doxycycline is the best antibiotic for it. In the cases it does not work, I believe Rifampin is used. If a positive is greater than 1:120 (I am going from memory) then 1:320 is high.
Are you seeing a Lyme doctor? Is he/she planning on addressing co-infections first? Do you have any other co-infections?