Yes, my first Lyme symptom was wandering leg pains that mimics sciatica...usually worse in the evening/night, picks one leg or the other, or starts in both and then settles on one side or the other. Affected area is low back all the way down to tips of my toes. Chiropractors have sworn they could "cure" it but their treatments did not help. Now I know why - it is the wandering joint pains of Lyme.
What helps me: Heat - heating pad on my lower back. Homeopathic Causticum, if I take it when the pain first starts. Exercise (low back stretches, etc.). And the pain has not occurred as frequently since I've been on antibiotics. I think Nettles also may help with my pain.
Your experience may be different from mine - if indeed your issue is truely sciatica and not the strange leg pains like what I've gotten.
Chronic Lyme Disease, Chronic Bartonella (clinical dx only), Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD ("Secondary Lupus-Like Syndrome"), Osteoporosis, chronic Lymphopenia, etc.; G-Tube; Currently trying to wean off TPN.
Meds: Pulmicort, IV Ceftazidime, Heparin (to flush PICC line), Claritin, Domperidone, Colloidal Silver (used topically), probiotics, Milk Thistle, Ailanthus, homeopathy.