I had an initial alergic reaction to IV-Rocephin where I broke out in hives immediately when dosing, fortunately they disapated quickly and I eventually stopped having the reaction after my body had a few days to adjust to the medication. I remember not feeling very well until the third week when I started to notice some improvement in my symptoms. The fourth week I felt even better however, my ID doc would not agree to extend the treatment beyond 30 days and had my picc line pulled. Now five months later, my new LLMD has started me on high dose oral abx treatment.
I expect that you will notice some improvement after continuing with the treatment for a while.
Hope that you feel better soon!
Peace and Healing
Lyme Disease - Doxycyline, IV-Rocephin, Amoxicillin, Azithromycin.