you can view the article below. Link did work last night, not sure why it doesn't now!
Public Health alert, v. 4, no. 7, 2009
by Scott Forsgren
Those of us with chronic Lyme disease are quite familiar with
the names of the better known Lyme co‐infections.
much as we would like to rid ourselves of these illnessproducing
pathogens, they have become a part of our daily
struggle to regain a sense of health and wellness.
Unfortunately, these are not the only co‐infections seen in
chronic Lyme disease. For some reason,
infections are not only lesser known by patients, but seemingly
often overlooked by doctors as well. It is important for us, as
patients, to educate ourselves on the topic of
to ask our practitioners how we are being evaluated and
treated for these infections.
In 1987, Dr. Garth Nicolson, PhD was a professor at the
University of Texas at Houston when his wife, an instructor at
Baylor College of Medicine, became seriously ill and nearly
died. She was diagnosed with a
and later recovered. A few years later, their daughter, who
had served in the Gulf War, returned from active duty quite ill. Not only was she sick, but the symptoms that
she exhibited were very similar to those that Dr. Nicolson’s wife had expressed years earlier.
At that point, Dr. Nicolson had the idea that his daughter’s illness could be the result of an infection and
started to investigate his theory further. As his work progressed, he looked at
and other chronic intracellular infections that have the potential to cause illness and present with
overlapping signs and symptoms. In Gulf War veterans that were being evaluated, approximately 45% of
hose that were ill had
Very little was known about this particular species of
Institute of Pathology and the Army had been doing research on the organism. Once this likely causative
agent of Gulf War Illness (GWI) had been identified in about one‐half of the GWI cases, Dr. Nicolson
recommended that the
himself the target of viscous attacks for making the connection between the illness and
Nicolson shared that “even talking about this organism was highly discouraged.” In fact, until the Gulf War,
the military’s own medical school had been teaching about the dangers of
Just years earlier in Texas, prisons emerged in which many of the inmates and guards came down with
neurodegenerative conditions at rates that were far from ordinary. In Huntsville, where three large State
prisons are found, there were about 70 cases of ALS, numerous cases of Multiple Sclerosis, and highly
nexpected numbers of Rheumatoid Arthritis cases. At that time, the term “Mystery Disease” was used to uidentify the unusual illnesses that so many seemed to have acquired.
Dr. Nicolson started testing prison guards and their family members and found that very high numbers of
these people were testing positive for
weaponized version of the organism called
been altered to cause more severe symptoms, to be more virulent, and to be more survivable than the
carried out on inmates in the Texas prison system for years in which humans had been used as guinea
As time progressed, these illnesses did not remain confined to the prisoners. Soon after the prisoners
unknowingly became a part in these experiments, the prison guards became ill. Their illnesses gradually
ecame those of their b families. It was not long before these
part of the surrounding Huntsville, Texas landscape.
The Texas prisoners that came down with Amyotrophic Lateral Sclerosis (ALS) later died. In the state of
Texas at the time, the state law dictated that all prisoners that died were later to be autopsied at University of
Texas at Galveston. However, that was not what was happening to the prisoners who had died as a result of
this horrific experimentation according to Dr. Nicolson. Through one of his former students who at the time
was responsible for the autopsy service at UT Galveston, Dr. Nicolson learned that none of the bodies had
been sent there. Dr. Nicolson had discovered that at least six private autopsies a week were being performed
on deceased prisoners at a US Army base. The bodies were then sent to a private crematory at a secret
location in central Texas. Additionally, prisoner records were destroyed. All of this, according to Dr.
Nicolson, violated state law.
Though much of the evidence of this experimentation had been destroyed, a document was found in the
basement of an Austin building that was viewed as the “moking gun” The document indicated that the
Texas Prison Board, Baylor College of Medicine, and the Department of Defense were all a part of the
experiments involving the Texas prisoners ‐ experiments that later resulted in the death of many of the
inmates. According to Dr. Nicolson, some of the experiments used
“cocktails of microbial agents” such as
project later become the topic of a book by Dr. Nicolson entitled
Dr. Nicolson believes that
strains that exist today have been weaponized. Dr. Nicolson’s research found unusual genes in
in an attempt to make a germ more pathogenic, immunosuppressive, resistant to heat and dryness, and to
increase its survival rate such that the germ could be used in various types of weapons. Genes which were
part of the HIV‐1 envelope gene were found in these
someone HIV, but that it may result in some of the debilitating symptoms of the HIV disease. Indicators of a
weaponized organism were evident in the prison guards in Huntsville as well as in military personnel that
were likely exposed to the infections both through military vaccinations as well as through weapons used in
the Gulf War.
The unfortunate reality according to Dr. Nicolson is that “once these things get out, you can’t put the genie
back in the bottle”. Once these germs have been released, they are airborne infections that slowly penetrate
into the population. In the case of
happened. It may be this weaponized form of
neurodegenerative and autoimmune diseases over the last several years. Those patients with weaponized
strains of these organisms are generally very sick. They may experience 60‐75 signs and symptoms and are
even at risk of their diseases becoming fatal.
In looking at the source of infection in the Gulf War veterans who were contracting
suggests that vaccinations appear to be the most likely mechanism through which the veterans became
infected. Many military personnel that later became ill were far from the battlefields or had received the
vaccinations and were never deployed. However, biological weapons sprayers were known to have been
deployed by the Iraqis in the Gulf War and were used to spray the sand in Iraq and Kuwait. Gerald
Mycoplasma – Often Overlooked In Chronic Lyme Disease
Schumacher, a Special Forces colonel in charge of biological weapons detection, blew the whistle on this after
e retired. During h the Gulf War, his group was not allowed to deploy their biological weapons detectors
which led to reports that no such weapons were detected or used.
The Iraqis received a great deal of assistance on biological warfare from the United States during the Iran‐
Iraq Conflict. Both chemical and biologic weapons were given to them from the United States. After the Gulf
War, rather than taking inventory of these weapons, they were blown up. Dr. Nicolson indicates that some of
his patients have taken videos standing next to crates with Hazardous Materials tags from the United States.
In the same videos, the crates are opened and weapons are clearly striped as having originated from the
United States and being both chemical and biological weapons.
There were clear indicators that Iraq had offensive weapons in their arsenal. In Kuwait, many people had
become quite ill. It was estimated that 25% of the population after the Gulf War had signs and symptoms
which matched the symptoms of those infected with weaponized
other chemical exposures and thus, there was never a clear indicator as to whether or not the Iraqi illnesses
were caused by biologic or chemical agents.
When asking Dr. Nicolson how much he personally has been harassed for bringing much of this information
to light, he shared that it has been “a horrific time”. After Dr. Nicolson exposed the Huntsville prison
experiments, the University of Texas educational system attempted to fire him from his tenured and highly
respected position. Dr. Nicolson shared that a tremendous amount of pressure was put on the University of
Texas system to “shut him up and close his laboratory”. He was threatened on an almost daily basis with
closing his lab as he continued to do his research on
Project Day Lily
knowledge continue to be a benefit in that we understand so much more than we otherwise would about this
formidable foe called
The signs and symptoms of
diagnosis to be entirely missed. A partial list of symptoms includes chronic fatigue, joint pain, intermittent
fevers, headaches, coughing, nausea, gastrointestinal problems, diarrhea, visual disturbances, memory loss,
sleep disturbances, skin rashes, joint stiffness, depression, irritability, congestion, night sweats, loss of
concentration, muscle spasms, nervousness, anxiety, chest pain, breathing irregularities, balance problems,
light sensitivity, hair loss, problems with urination, congestive heart failure, blood pressure abnormalities,
lymph node pain, chemical sensitivities, persistent coughing, eye pain, floaters in the eyes, and many others.
On Dr. Nicolson’s web site at
form can be found.
It doesn’t take long to see that the symptoms of
neurodegenerative diseases and the infections that are associated with each.
n patients with ALS, Multiple Sclerosis, Autism, Chronic Fatigue Syndrome, Rheumatoid Arthritis, Chronic
sthma, Lyme disease, and many other chronic disease conditions.
Illness Infections Commonly Observed
Amyotrophic Lateral Sclerosis (ALS)
HHV6, Chlamydia pneumoniae
Multiple Sclerosis (MS)
Autism Spectrum Disorders
HHV6, Borrelia burgdorferi
Chronic Fatigue Syndrome
Chronic illnesses and infections commonly observed in each according to the work of Dr. Garth Nicolson, PhD
against this type of bacteria. There are over 100 known species of
are known to be pathogenic in humans
survive. Once they are inside the cells, they are not recognized by the immune system and it is difficult to
mount an effective response.
They stimulate reactive‐oxygen species (ROS) which damage cell membranes. They release toxins into the
body. Infected cells can be stimulated to undergo programmed cell death which may result in ALS or other
severe neurological presentations. 90% of ALS patients evaluated were found to have
They are thought of as “borderline anaerobes” meaning that they generally prefer low oxygen environments.
Dr. Nicolson has found that airline employees are much more susceptible to these types of infections and that
ymptoms worsen with frequent long flights at low oxygen tension.
c cs of viruses.
Gulf War veterans, the first person besides the veteran to become ill was the spouse and later, other members
f the household also became ill. Not everyone is equally susceptible to
une systems who can re
those with strong imm sist infection.
As already discussed,
found to be asymptomatic. In North America,
various diseases. In Europe,
lower than in North America.
The potential genetic factors involved in
deficiencies and other illnesses, such as cancers and degenerative diseases, are at far greater risk of infection.
In one study looking at
some interesting patterns in his research. Generally, the majority of CFS patients have
However, CFS patients infected with
Lyme disease, neurodegenerative diseases, and many other chronic illnesses lear origins.
Even more startling was the finding that of that of the patients infected with
patients had the
Chronic Fatigue patients that did not test positive for
ormal, healthy controls, only 1.7% were found to have
ate of 5% compared to the 75% group mentioned earlier.
Dr. Nicolson notes that these findings are consistent with the fact that it is the
that is more often isolated in ticks collected from the environment. The same tick that serves as the vector for
infected, the duration and severity of their illn
In his experience, Dr. Nicolson has found that
f infection with
and that of
According to Dr. Nicolson, a healthy immune system can generally clear
ave a harder time eradicating
heck ‐ essentially having the infection but not expressing symptoms.
Incidence of Various Microbes in Patients with Lyme Disease – G. L. Nicolson
Dr. Nicolson noted that
because they simply don’t test for it. He states that those that do test for it find a much higher number of
infected patients. Dr. Richard Horowitz, MD in New York finds a high incidence of
Sadly, however, even if patients are tested for
almost all Lyme doctors and patients are aware of – namely that reliable tests do not exist. Dr. Nicolson
notes that once a laboratory gets a reliable test in place, the laboratory is often shutdown. There are only a
few labs left that test for
In testing ticks for various microbial species, Dr. Nicolson has found a very high incidence of
The incidence of these other species is far lower. “Far and away”, it is the
in ticks, and this probably reflects the high incidence of
In terms of laboratory testing, Dr. Nicolson generally recommends Viral Immune Pathology, formerly known
as RedLabs. He has found that the usefulness of any given lab in testing for
n the past, Dr. Nicolson used Medical Diagnostic Laboratories (MDL) for testing, but later he and other
physicians found that the testing was no longer re s a result, he no longer recommends MDL.
Dr. Nicolson finds that laboratories testing for
may affect the way the labs test and report this type of infection.
Thomas McPherson Brown, MD studied
was able to isolate bacteria from the joint fluid of a person with autoimmune arthritis and believed that the
infection could have been the trigger for her disease. At the time, the organisms were too small to identify
precisely, but it was later determined to be
Even then, Dr. Brown believed that
using tetracycline drugs as an effective treatment for the disease. He later found that Doxycycline and
Minocycline were effective at dealing with
generally regarded by the medical community as misguided and a trouble‐maker. He died in 1989 prior to
eing fully vindicated. Fortunately, his work was validated through an NIH‐sponsored study called MIRA or
“inocycline in Rheumatoid Arthritis
Due to many of the characteristics of
autoimmune responses. As
antigens from the surface of the host cell and incorporate these antigens into their own membranes. This
makes it almost impossible for the body to tell the difference between good and bad, between human and
microbe, or between us and them. As a result, the immune system may begin to respond to these antigens
now incorporated into the cell walls of the bacteria and create a condition of self‐attack, or autoimmunity.
The microorganisms can produce mimicry antigens that mimic the natural host surface antigens and trigger
an immune response to these antigens which may also result in autoimmune conditions through crossreactivity.
or programmed cell death.
Though various strains of
tends to be quite similar. The variations in the strains do not appear to be a factor in a successful treatment
Dr. Nicolson suggests that
differences have been found but that it is not possible to easily extrapolate
these findings to an
environment. Various factors including drug targeting, drug clearance, and the
ability for the drug to cross into various body compartments are important considerations in treatment that
cannot be examined
Dr. Nicolson believes that, like many other coinfections of Lyme disease,
eradicated, but that once infected, treatment becomes an ongoing “management approach”. He notes that
this is a commonly understood fact and that the same is true of other organisms such as
ther antibiotic ms.
Once in these locations, nei s nor the immune system can effectively reach or kill the organis
Many people recover from
involving severe trauma or other significant life stressor and symptoms fully reappear within weeks to
Dr. Nicolson recommends that the physician adopt an initial 6‐month course of treatment with no break
followed by several 6‐week on, 2‐week off antibiotic cycles. Candidate antibiotics include: Doxycycline,
Ciprofloxacin (Cipro), Azithromycin (Zithromax), Minocycline, or Clarithromycin (Biaxin). He notes that
antibiotic combinations may be required if there is a limited response to single drug, and most patients
equire switching antibiotics at least once during their treatment. Some patients may find the addition of
lagyl to be a benefit to treatment.
In Gulf War patients, once effectively treated, the majority of patients recovered. For civilians, six months is
the minimum recommended treatment length, and some patients require much longer treatment in order to
Ganciclovir may be added to the antibiotic ther
Herxheimer reactions do occur when treating
the patient generally feels much worse while on treatment, Dr. Nicolson advises using 50mg oral Benadryl
taken 30 minutes before the antibiotics. He also finds that a strained blend of 1 whole lemon, 1 cup fruit juice,
and 1 tablespoon of olive oil can be helpful.
Though Dr. Nicolson believes that antibiotics are the most effective approach to treating
infections, he has found some good natural options. In terms of natural approaches to treating
Raintree Nutrition (
patients. These include Raintree Myco, Raintree A‐F, and Raintree Immune Support.
Dr. Nicolson has seen evidence that
and others can be beneficial in some patients. He says that many natural options help in some patients, but
that his experience has been that the antibiotic treatment results in the best outcomes. In many, recovery
requires a push and pull between conventional and alternative treatments.
One of the hallmark signs of
leads to damage of the cell membranes. Oxidation accelerates the damage to the lipids in cell membranes
which impacts mitochondrial function. This leads to less energy in the cell and ultimately to a fatiguing of the
larger organism due to the fact that there is less energy to support necessary cellular functions.
In patients where fatigue is due to cell membrane damage, Dr. Nicolson has found NT Factor® to be highly
beneficial. NT Factor® replaces the damaged lipids and helps to restore mitochondrial function. Often,
fatigue then resolves or is reduced.
Dr. Nicolson has found that oxidative therapies such as ozone can be helpful in the fight against
However, he notes that this is generally palliative and does not produce the same results as the antibiotic
therapy in the long‐term. He finds that the oxidative therapies “re generally more cytostatic than cytotoxic”
Hyperbaric oxygen may be helpful but similarly does not appear to be a highly effective treatment in the
In other countries, IV drips with H2O2 (hydrogen peroxide) have been used with some benefit, but Dr.
Nicolson notes that these therapies, while potentially effective, are highly dangerous and not advised.
In the realm of frequency medicine and Rife therapy, Dr. Nicolson believes that the frequencies that could be
used to address
therapy is an effective way to approach the problem.
In the nutritional realm, Dr. Nicolson finds that many patients with chronic infections are immunosuppressed
and that proper nutrition is vital. He cautions against smoking and drinking. He suggests avoidance of sugars
trans‐fats, and allergenic foods. He advises patients to increase their fruits, vegetables, and whole grains.
ome dietary winners in supporting the immune system include cruciferous vegetables, soluble fiber‐based
oods such as prunes and bran, wheat germ, yogurt, fish, and whole grains.
None of these treatments are a panacea.
It takes a combination of things to resolve a patient’s symptoms.
Patients are often depleted in key vitamins and minerals. Supplementation with B‐Complex, Vitamin C,
Vitamin E, and CoQ‐10 are often beneficial. Minerals are often necessary. Dr. Nicolson notes, however, that
many people have poor absorption and may require sublingual or injectable forms of these nutrients. Amino
cids, flax seed, and fish oils can a provide additional support, but the best nutrition for cell membranes is NT
Many patients with chronic illnesses have a toxic body burden of heavy metals such as mercury, lead,
cadmium, and aluminum. Hair, stool, and urine testing is available through labs like Doctor’ Data
of positive results with EDTA chelation suppositories from Detoxamin (
chelators from Longevity Plus (
For patients using antibiotics, beneficial gut flora is often depressed. Supplementation with a high quality
probiotic is important, but probiotics have to be taken two hours or longer after taking antibiotics. Natural
immune support can be helpful in the form of whey proteins, transfer factors, or immune‐support products
such as Beyond Immuni‐T from Longevity Plus.
Dr. Nicolson believes that biofilms are a factor in successfully treating
are refractory to antibiotics, biofilms are likely a major factor.
In men with chronic refractory prostatitis which is infection‐based, one often cannot be treated effectively
with antibiotics. However, when Detoxamin (EDTA) or other agents to address the biofilms are used, it then
becomes possible to treat these infections with tetracyclines. Patients quickly show functional increases and
decreases in pain other symptoms.
In chronic Lyme disease, it is often difficult to know which infections are actually responsible for the
persistence of illness. However, in general terms, chronic intracellular infections that change the metabolism
of cells and suppress mitochondrial and other functions will lead to patients remaining in a chronically ill
state. Dr. Nicolson believes that these infections must be aggressively treated. “Similar to chronic Lyme
disease, the current CDC or IDSA recommendations for short‐term treatment of chronic infections are simply
Dr. Nicolson has found that there is a hierarchy of symptoms that resolve relatively quickly and those that
resolve more slowly when treating
Syndrome (IBS) often resolve quickly. Other systemic signs and symptoms can resolve in an intermediate
period of time from many weeks to many months. Symptoms associated with the central and peripheral
nervous systems such as neuropathy and pain often resolve much more slowly. Skin sensitivity and burning
sensations may take much longer to resolve.
symptoms are among the more difficult to resolve.
Dr. Nicolson states “e keep seeing the suppression of information on
bacterial infections. The world of
politics involved. Physicians are being persecuted by their medical boards as a result of bad information. It is
important for us to do everything within our power to get rid of harmful, erroneous information about these
result, both are politically incorrect to discuss, work on, or do anything about. Until this changes, we won’t
see any real progress.”
Professor Garth L. Nicolson is the President, Chief Scientific Officer and Research Professor at the Institute for
Molecular Medicine in Huntington Beach, California. Born in 1943 in Los Angeles, Dr. Nicolson received his
B.S. in Chemistry from University of California at Los Angeles in 1965 and his Ph.D. in Biochemistry and Cell
Biology from the University of California at San Diego in 1970. Professor Nicolson has published over 580
medical and scientific papers, edited 15 books, and served on the Editorial Boards of 30 medical and scientific
journals. He is also a Colonel (Honorary) of the U. S. Army Special Forces and a U. S. Navy SEAL (Honorary) for
is work on Armed Forces and veterans’ illnesses. More information on Dr. Nicolson’s work can be found on
his web si
Scott Forsgren is the editor and founder of BetterHealthGuy.com where he shares his twelve
year journey through a chronic illness only diagnosed as Lyme disease after eight years of
searching for answers. Scott can be reached at
Additional information on NT Factor® can be found at
Post Edited (Simela) : 9/3/2010 10:43:41 AM (GMT-6)
Post Edited (Simela) : 9/6/2010 5:39:52 PM (GMT-6)
Post Edited (Simela) : 9/7/2010 2:08:34 PM (GMT-6)