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Simela
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Date Joined Aug 2010
Total Posts : 552
   Posted 9/2/2010 11:17 PM (GMT -6)   
 

you can view the article below.  Link did work last night, not sure why it doesn't now!Mycoplasma – Often Overlooked In Chronic Lyme Disease

Public Health alert, v. 4, no. 7, 2009

Mycoplasma – Often Overlooked In Chronic Lyme

Disease

by Scott Forsgren

Those of us with chronic Lyme disease are quite familiar with

the names of the better known Lyme co‐infections. Babesia,

Bartonella, and Ehrlichia have become everyday words. As

much as we would like to rid ourselves of these illnessproducing

pathogens, they have become a part of our daily

struggle to regain a sense of health and wellness.

Unfortunately, these are not the only co‐infections seen in

chronic Lyme disease. For some reason, Mycoplasma

infections are not only lesser known by patients, but seemingly

often overlooked by doctors as well. It is important for us, as

patients, to educate ourselves on the topic of Mycoplasma and

to ask our practitioners how we are being evaluated and

treated for these infections.

In 1987, Dr. Garth Nicolson, PhD was a professor at the

University of Texas at Houston when his wife, an instructor at

Baylor College of Medicine, became seriously ill and nearly

died. She was diagnosed with a Mycoplasma infection, treated,

and later recovered. A few years later, their daughter, who

had served in the Gulf War, returned from active duty quite ill. Not only was she sick, but the symptoms that

she exhibited were very similar to those that Dr. Nicolson’s wife had expressed years earlier.

At that point, Dr. Nicolson had the idea that his daughter’s illness could be the result of an infection and

started to investigate his theory further. As his work progressed, he looked at Brucella, Borrelia, Ehrlichia,

and other chronic intracellular infections that have the potential to cause illness and present with

overlapping signs and symptoms. In Gulf War veterans that were being evaluated, approximately 45% of

hose that were ill had Mycoplasma infection. It was found that the infection was a particular type of

sma ferment

t

Mycoplasma, namely a peculiar species called Mycopla ans.

Very little was known about this particular species of Mycoplasma at the time except that the Armed Forces

Institute of Pathology and the Army had been doing research on the organism. Once this likely causative

agent of Gulf War Illness (GWI) had been identified in about one‐half of the GWI cases, Dr. Nicolson

recommended that the Mycoplasma‐infected Gulf War veterans be treated with Doxycycline. He then found

himself the target of viscous attacks for making the connection between the illness and M. fermentans. Dr.

Nicolson shared that “even talking about this organism was highly discouraged.” In fact, until the Gulf War,

the military’s own medical school had been teaching about the dangers of M. fermentans for years.

Background

Just years earlier in Texas, prisons emerged in which many of the inmates and guards came down with

neurodegenerative conditions at rates that were far from ordinary. In Huntsville, where three large State

prisons are found, there were about 70 cases of ALS, numerous cases of Multiple Sclerosis, and highly

nexpected numbers of Rheumatoid Arthritis cases. At that time, the term “Mystery Disease” was used to uidentify the unusual illnesses that so many seemed to have acquired.

Dr. Nicolson started testing prison guards and their family members and found that very high numbers of

these people were testing positive for Mycoplasma fermentans. Furthermore, this appeared to be a

weaponized version of the organism called M. fermentans incognitus, a specific strain of Mycoplasma that had

2 Mycoplasma – Often Overlooked In Chronic Lyme Disease

been altered to cause more severe symptoms, to be more virulent, and to be more survivable than the

aturally occurring M. fermentans. Dr. Nicolson believed that biological weapons experiments had been

pigs.

n

carried out on inmates in the Texas prison system for years in which humans had been used as guinea

As time progressed, these illnesses did not remain confined to the prisoners. Soon after the prisoners

unknowingly became a part in these experiments, the prison guards became ill. Their illnesses gradually

ecame those of their b families. It was not long before these Mycoplasma‐based illnesses became a broader

part of the surrounding Huntsville, Texas landscape.

The Texas prisoners that came down with Amyotrophic Lateral Sclerosis (ALS) later died. In the state of

Texas at the time, the state law dictated that all prisoners that died were later to be autopsied at University of

Texas at Galveston. However, that was not what was happening to the prisoners who had died as a result of

this horrific experimentation according to Dr. Nicolson. Through one of his former students who at the time

was responsible for the autopsy service at UT Galveston, Dr. Nicolson learned that none of the bodies had

been sent there. Dr. Nicolson had discovered that at least six private autopsies a week were being performed

on deceased prisoners at a US Army base. The bodies were then sent to a private crematory at a secret

location in central Texas. Additionally, prisoner records were destroyed. All of this, according to Dr.

Nicolson, violated state law.

Though much of the evidence of this experimentation had been destroyed, a document was found in the

basement of an Austin building that was viewed as the “moking gun” The document indicated that the

Texas Prison Board, Baylor College of Medicine, and the Department of Defense were all a part of the

experiments involving the Texas prisoners ‐ experiments that later resulted in the death of many of the

inmates. According to Dr. Nicolson, some of the experiments used Mycoplasma while others utilized various

“cocktails of microbial agents” such as Mycoplasma, Brucella, and DNA viruses such as Parvovirus B19. This

project later become the topic of a book by Dr. Nicolson entitled Project Day Lily.

Dr. Nicolson believes that Mycoplasma fermentans is a naturally occurring microbe. However, some of the

strains that exist today have been weaponized. Dr. Nicolson’s research found unusual genes in M. fermentans

incognitus that were consistent with a weaponized form of the organism. Weaponzing of an organism is done

in an attempt to make a germ more pathogenic, immunosuppressive, resistant to heat and dryness, and to

increase its survival rate such that the germ could be used in various types of weapons. Genes which were

part of the HIV‐1 envelope gene were found in these Mycoplasma. This means that the infection may not give

someone HIV, but that it may result in some of the debilitating symptoms of the HIV disease. Indicators of a

weaponized organism were evident in the prison guards in Huntsville as well as in military personnel that

were likely exposed to the infections both through military vaccinations as well as through weapons used in

the Gulf War.

The unfortunate reality according to Dr. Nicolson is that “once these things get out, you can’t put the genie

back in the bottle”. Once these germs have been released, they are airborne infections that slowly penetrate

into the population. In the case of Mycoplasma fermentans, Dr. Nicolson believes that this is exactly what

happened. It may be this weaponized form of Mycoplasma that has led to the significant increases in

neurodegenerative and autoimmune diseases over the last several years. Those patients with weaponized

strains of these organisms are generally very sick. They may experience 60‐75 signs and symptoms and are

even at risk of their diseases becoming fatal.

In looking at the source of infection in the Gulf War veterans who were contracting Mycoplasma, Dr. Nicolson

suggests that vaccinations appear to be the most likely mechanism through which the veterans became

infected. Many military personnel that later became ill were far from the battlefields or had received the

vaccinations and were never deployed. However, biological weapons sprayers were known to have been

deployed by the Iraqis in the Gulf War and were used to spray the sand in Iraq and Kuwait. Gerald

Mycoplasma is the number one coinfection observed in Lyme disease patients

3

Mycoplasma – Often Overlooked In Chronic Lyme Disease

Schumacher, a Special Forces colonel in charge of biological weapons detection, blew the whistle on this after

e retired. During h the Gulf War, his group was not allowed to deploy their biological weapons detectors

which led to reports that no such weapons were detected or used.

The Iraqis received a great deal of assistance on biological warfare from the United States during the Iran‐

Iraq Conflict. Both chemical and biologic weapons were given to them from the United States. After the Gulf

War, rather than taking inventory of these weapons, they were blown up. Dr. Nicolson indicates that some of

his patients have taken videos standing next to crates with Hazardous Materials tags from the United States.

In the same videos, the crates are opened and weapons are clearly striped as having originated from the

United States and being both chemical and biological weapons.

There were clear indicators that Iraq had offensive weapons in their arsenal. In Kuwait, many people had

become quite ill. It was estimated that 25% of the population after the Gulf War had signs and symptoms

which matched the symptoms of those infected with weaponized Mycoplasma. There were also a number of

other chemical exposures and thus, there was never a clear indicator as to whether or not the Iraqi illnesses

were caused by biologic or chemical agents.

When asking Dr. Nicolson how much he personally has been harassed for bringing much of this information

to light, he shared that it has been “a horrific time”. After Dr. Nicolson exposed the Huntsville prison

experiments, the University of Texas educational system attempted to fire him from his tenured and highly

respected position. Dr. Nicolson shared that a tremendous amount of pressure was put on the University of

Texas system to “shut him up and close his laboratory”. He was threatened on an almost daily basis with

closing his lab as he continued to do his research on Mycoplasma. This became a major subject in the book

Project Day Lily. Fortunately, for many of us struggling with chronic illnesses, Dr. Nicolson’s experience and

knowledge continue to be a benefit in that we understand so much more than we otherwise would about this

formidable foe called Mycoplasma.

Symptoms

The signs and symptoms of Mycoplasma infection are highly variable and thus it is not uncommon for a

diagnosis to be entirely missed. A partial list of symptoms includes chronic fatigue, joint pain, intermittent

fevers, headaches, coughing, nausea, gastrointestinal problems, diarrhea, visual disturbances, memory loss,

sleep disturbances, skin rashes, joint stiffness, depression, irritability, congestion, night sweats, loss of

concentration, muscle spasms, nervousness, anxiety, chest pain, breathing irregularities, balance problems,

light sensitivity, hair loss, problems with urination, congestive heart failure, blood pressure abnormalities,

lymph node pain, chemical sensitivities, persistent coughing, eye pain, floaters in the eyes, and many others.

On Dr. Nicolson’s web site at http://www.immed.org, a full list of signs and symptoms and an illness survey

form can be found.

It doesn’t take long to see that the symptoms of Mycoplasma infections are very similar to the symptoms of

Borrelia infections in chronic Lyme disease. Dr. Nicolson has looked at some of the more common

neurodegenerative diseases and the infections that are associated with each. Mycoplasma is commonly found

n patients with ALS, Multiple Sclerosis, Autism, Chronic Fatigue Syndrome, Rheumatoid Arthritis, Chronic

sthma, Lyme disease, and many other chronic disease conditions.

i

A

Illness Infections Commonly Observed

Amyotrophic Lateral Sclerosis (ALS) Mycoplasma fermentans (and other species), Borrelia burgdorferi,

HHV6, Chlamydia pneumoniae

Multiple Sclerosis (MS) Chlamydia pneumoniae, Mycoplasma species, Borre rferi,

nd other Herpes viruses

lia burgdo

HHV6 a

Alzheimer’s Disease Chlamydia pneumoniae, Borrelia burgdorferi, HSV1 and other Herpes

viruses

Parkinson’s Disease Helicobacter pylori, coronavirus, Mycoplasma species

Autism Spectrum Disorders Mycoplasma fermentans (and other species), Chlamydia pneumoniae,

HHV6, Borrelia burgdorferi

Chronic Fatigue Syndrome Mycoplasma pneumoniae (and other species), Chlamydia pneumoniae,

4

Mycoplasma – Often Overlooked In Chronic Lyme Disease

Borrelia burgdorferi

Lyme Disease Borrelia burgdorferi, Mycoplasma fermentans (and other species),

Babesia species, Bartonella species, Ehrlichia species

Chronic illnesses and infections commonly observed in each according to the work of Dr. Garth Nicolson, PhD

Characteristics

Mycoplasma are pleomorphic bacteria which lack a cell wall and as a result, many antibiotics are not effective

against this type of bacteria. There are over 100 known species of Mycoplasma, but only a half dozen or so

are known to be pathogenic in humans. The pathogenic species are intracellular and must enter cells to

survive. Once they are inside the cells, they are not recognized by the immune system and it is difficult to

mount an effective response.

They stimulate reactive‐oxygen species (ROS) which damage cell membranes. They release toxins into the

body. Infected cells can be stimulated to undergo programmed cell death which may result in ALS or other

severe neurological presentations. 90% of ALS patients evaluated were found to have Mycoplasma infections,

whereas Mycoplasma was found in 100% of ALS patients with Gulf War Syndrome, almost all of which were

weaponized M. fermentans incognitus.

They are thought of as “borderline anaerobes” meaning that they generally prefer low oxygen environments.

Dr. Nicolson has found that airline employees are much more susceptible to these types of infections and that

ymptoms worsen with frequent long flights at low oxygen tension. Mycoplasma also have some

haracteristi

s

c cs of viruses.

Mycoplasma tend to be slow growing infections and they are usually transmitted slowly. Dr. Nicolson states

that “Mycoplasma can be sexually transmitted, but the infection is usually passed through far less intimate

contact. Mycoplasma can be obtained through fluid exchange, and it is easily transmitted through the air.” In

Gulf War veterans, the first person besides the veteran to become ill was the spouse and later, other members

f the household also became ill. Not everyone is equally susceptible to Mycoplasma infections, especially

une systems who can re

o

those with strong imm sist infection.

As already discussed, Mycoplasma fermentans produces numerous symptoms. Those infected are rarely

found to be asymptomatic. In North America, M. pneumoniae is the most common Mycoplasma seen in

various diseases. In Europe, M. hominis is far more prevalent and the incidence of M. fermentans is much

lower than in North America.

The potential genetic factors involved in Mycoplasma illnesses are not known. Those with immune

deficiencies and other illnesses, such as cancers and degenerative diseases, are at far greater risk of infection.

Prevalence

In one study looking at Mycoplasma in patients with Chronic Fatigue Syndrome, Dr. Nicolson has observed

some interesting patterns in his research. Generally, the majority of CFS patients have Mycoplasma infections.

However, CFS patients infected with Borrelia burgdorferi, the punitive agent in Lyme disease, had an even

higher overall Mycoplasma infection rate. As many as 75% of Lyme disease patients appear to have

ycoplasma infections, and yet Mycoplasma is often overlooked in the diagnosis and treatment of chronic

lacking c

M

Lyme disease, neurodegenerative diseases, and many other chronic illnesses lear origins.

Even more startling was the finding that of that of the patients infected with Borrelia, over 50% of the

patients had the M. fermentans infection. Approximately 23% carried M. pneumoniae.

Chronic Fatigue patients that did not test positive for Borrelia had much more of a mixture of various species

of Mycoplasma. Only 28% of the group not co‐infected with Lyme disease had the M. fermentans infection. In

ormal, healthy controls, only 1.7% were found to have M. fermentans and at a total Mycoplasma infection

ate of 5% compared to the 75% group mentioned earlier.

nr

5

Mycoplasma – Often Overlooked In Chronic Lyme Disease

Dr. Nicolson notes that these findings are consistent with the fact that it is the Mycoplasma fermentans species

that is more often isolated in ticks collected from the environment. The same tick that serves as the vector for

orrelia burgdorferi often also transmits M. fermentans simultaneously. Once a patient is multiply coess

both increase.

B

infected, the duration and severity of their illn

In his experience, Dr. Nicolson has found that Mycoplasma is the number one Lyme coinfection. The rate

f infection with Mycoplasma in patients with Lyme disease surp o asses that of Bartonella (25‐40%) slightly

and that of Babesia (8‐20%) significantly.

According to Dr. Nicolson, a healthy immune system can generally clear M. pneumoniae infections though will

ave a harder time eradicating M. fermentans on its own. Healthy people can often hold these infections in

heck ‐ essentially having the infection but not expressing symptoms.

hc

Incidence of Various Microbes in Patients with Lyme Disease – G. L. Nicolson

Testing

Dr. Nicolson noted that Mycoplasma infections in chronic Lyme disease are often overlooked by most doctors

because they simply don’t test for it. He states that those that do test for it find a much higher number of

infected patients. Dr. Richard Horowitz, MD in New York finds a high incidence of M. fermentans according to

Dr. Nicolson.

Sadly, however, even if patients are tested for Mycoplasma, a similar problem exists here as the one that

almost all Lyme doctors and patients are aware of – namely that reliable tests do not exist. Dr. Nicolson

notes that once a laboratory gets a reliable test in place, the laboratory is often shutdown. There are only a

few labs left that test for Mycoplasma as a result.

In testing ticks for various microbial species, Dr. Nicolson has found a very high incidence of Mycoplasma

fermentans. However, other Mycoplasma species have also been found such as M. pneumoniae and M. hominis.

The incidence of these other species is far lower. “Far and away”, it is the M. fermentans species that is seen

in ticks, and this probably reflects the high incidence of M. fermentans coinfections in Lyme disease.

In terms of laboratory testing, Dr. Nicolson generally recommends Viral Immune Pathology, formerly known

as RedLabs. He has found that the usefulness of any given lab in testing for Mycoplasma changes regularly.

n the past, Dr. Nicolson used Medical Diagnostic Laboratories (MDL) for testing, but later he and other

liable. A

I

physicians found that the testing was no longer re s a result, he no longer recommends MDL.

Dr. Nicolson finds that laboratories testing for Mycoplasma are highly scrutinized by federal agencies and that

may affect the way the labs test and report this type of infection.

6

Mycoplasma – Often Overlooked In Chronic Lyme Disease

Autoimmunity

Thomas McPherson Brown, MD studied Mycoplasma at the Rockefeller Institute just before World War II. He

was able to isolate bacteria from the joint fluid of a person with autoimmune arthritis and believed that the

infection could have been the trigger for her disease. At the time, the organisms were too small to identify

precisely, but it was later determined to be Mycoplasma.

Even then, Dr. Brown believed that Mycoplasma was very common and not easy to eradicate. He suggested

using tetracycline drugs as an effective treatment for the disease. He later found that Doxycycline and

Minocycline were effective at dealing with Mycoplasma. Though he garnered praise from his patients, he was

generally regarded by the medical community as misguided and a trouble‐maker. He died in 1989 prior to

eing fully vindicated. Fortunately, his work was validated through an NIH‐sponsored study called MIRA or

b

“inocycline in Rheumatoid Arthritis

Due to many of the characteristics of Mycoplasma, they may be responsible for the triggering of numerous

autoimmune responses. As Mycoplasma replicate within cells and are eventually released, they capture

antigens from the surface of the host cell and incorporate these antigens into their own membranes. This

makes it almost impossible for the body to tell the difference between good and bad, between human and

microbe, or between us and them. As a result, the immune system may begin to respond to these antigens

now incorporated into the cell walls of the bacteria and create a condition of self‐attack, or autoimmunity.

The microorganisms can produce mimicry antigens that mimic the natural host surface antigens and trigger

an immune response to these antigens which may also result in autoimmune conditions through crossreactivity.

Additionally, Mycoplasma may cause cell death of host cells through a process known as apoptosis

or programmed cell death.

Treatment

Though various strains of Mycoplasma have their own unique characteristics and drug responses, treatment

tends to be quite similar. The variations in the strains do not appear to be a factor in a successful treatment

response.

Dr. Nicolson suggests that invitro

differences have been found but that it is not possible to easily extrapolate

these findings to an invivo

environment. Various factors including drug targeting, drug clearance, and the

ability for the drug to cross into various body compartments are important considerations in treatment that

cannot be examined invitro.

Dr. Nicolson believes that, like many other coinfections of Lyme disease, Mycoplasma cannot be fully

eradicated, but that once infected, treatment becomes an ongoing “management approach”. He notes that

this is a commonly understood fact and that the same is true of other organisms such as Chlamydia and

orrelia. Mycoplasma have the ability to go into a quiescent phase in intracellular locations within the body.

ther antibiotic ms.

B

Once in these locations, nei s nor the immune system can effectively reach or kill the organis

Many people recover from Mycoplasma infections and are fine for years. They may later have an incident

involving severe trauma or other significant life stressor and symptoms fully reappear within weeks to

months.

Dr. Nicolson recommends that the physician adopt an initial 6‐month course of treatment with no break

followed by several 6‐week on, 2‐week off antibiotic cycles. Candidate antibiotics include: Doxycycline,

Ciprofloxacin (Cipro), Azithromycin (Zithromax), Minocycline, or Clarithromycin (Biaxin). He notes that

antibiotic combinations may be required if there is a limited response to single drug, and most patients

equire switching antibiotics at least once during their treatment. Some patients may find the addition of

lagyl to be a benefit to treatment.

r

F

7

Mycoplasma – Often Overlooked In Chronic Lyme Disease

In Gulf War patients, once effectively treated, the majority of patients recovered. For civilians, six months is

the minimum recommended treatment length, and some patients require much longer treatment in order to

recover.

iven that Mycoplasma have some characteristics of viruses, some physicians have suggested that Famvir or

apy.

G

Ganciclovir may be added to the antibiotic ther

Herxheimer reactions do occur when treating Mycoplasma infections. To minimize this die‐off effect where

the patient generally feels much worse while on treatment, Dr. Nicolson advises using 50mg oral Benadryl

taken 30 minutes before the antibiotics. He also finds that a strained blend of 1 whole lemon, 1 cup fruit juice,

and 1 tablespoon of olive oil can be helpful.

Though Dr. Nicolson believes that antibiotics are the most effective approach to treating Mycoplasma

infections, he has found some good natural options. In terms of natural approaches to treating Mycoplasma,

Raintree Nutrition (http://www.rain‐tree.com) has created several products that may be quite helpful for

patients. These include Raintree Myco, Raintree A‐F, and Raintree Immune Support.

Dr. Nicolson has seen evidence that Mycoplasma‐specific transfer factors such as those from Chisholm Labs

and others can be beneficial in some patients. He says that many natural options help in some patients, but

that his experience has been that the antibiotic treatment results in the best outcomes. In many, recovery

requires a push and pull between conventional and alternative treatments.

One of the hallmark signs of Mycoplasma infection is fatigue. The infections lead to oxidation in the body that

leads to damage of the cell membranes. Oxidation accelerates the damage to the lipids in cell membranes

which impacts mitochondrial function. This leads to less energy in the cell and ultimately to a fatiguing of the

larger organism due to the fact that there is less energy to support necessary cellular functions.

In patients where fatigue is due to cell membrane damage, Dr. Nicolson has found NT Factor® to be highly

beneficial. NT Factor® replaces the damaged lipids and helps to restore mitochondrial function. Often,

fatigue then resolves or is reduced.

Dr. Nicolson has found that oxidative therapies such as ozone can be helpful in the fight against Mycoplasma.

However, he notes that this is generally palliative and does not produce the same results as the antibiotic

therapy in the long‐term. He finds that the oxidative therapies “re generally more cytostatic than cytotoxic”

Hyperbaric oxygen may be helpful but similarly does not appear to be a highly effective treatment in the

longer‐term.

In other countries, IV drips with H2O2 (hydrogen peroxide) have been used with some benefit, but Dr.

Nicolson notes that these therapies, while potentially effective, are highly dangerous and not advised.

In the realm of frequency medicine and Rife therapy, Dr. Nicolson believes that the frequencies that could be

used to address Mycoplasma are too similar to normal cellular frequencies. Thus, he is not certain that Rife

therapy is an effective way to approach the problem.

In the nutritional realm, Dr. Nicolson finds that many patients with chronic infections are immunosuppressed

and that proper nutrition is vital. He cautions against smoking and drinking. He suggests avoidance of sugars

trans‐fats, and allergenic foods. He advises patients to increase their fruits, vegetables, and whole grains.

ome dietary winners in supporting the immune system include cruciferous vegetables, soluble fiber‐based

oods such as prunes and bran, wheat germ, yogurt, fish, and whole grains.

Sf

None of these treatments are a panacea.

It takes a combination of things to resolve a patient’s symptoms.

8 Mycoplasma – Often Overlooked In Chronic Lyme Disease

Patients are often depleted in key vitamins and minerals. Supplementation with B‐Complex, Vitamin C,

Vitamin E, and CoQ‐10 are often beneficial. Minerals are often necessary. Dr. Nicolson notes, however, that

many people have poor absorption and may require sublingual or injectable forms of these nutrients. Amino

cids, flax seed, and fish oils can a provide additional support, but the best nutrition for cell membranes is NT

Factor®

Many patients with chronic illnesses have a toxic body burden of heavy metals such as mercury, lead,

cadmium, and aluminum. Hair, stool, and urine testing is available through labs like Doctor’ Data

(http://www.doctorsdata.com) and Genova Diagnostics (http://www.gdx.net). Dr. Nicolson has seen reports

of positive results with EDTA chelation suppositories from Detoxamin (http://www.detoxamin.com) and oral

chelators from Longevity Plus (http://www.longevityplus.com).

For patients using antibiotics, beneficial gut flora is often depressed. Supplementation with a high quality

probiotic is important, but probiotics have to be taken two hours or longer after taking antibiotics. Natural

immune support can be helpful in the form of whey proteins, transfer factors, or immune‐support products

such as Beyond Immuni‐T from Longevity Plus.

Biolfims

Dr. Nicolson believes that biofilms are a factor in successfully treating Mycoplasma infections. In cases that

are refractory to antibiotics, biofilms are likely a major factor.

In men with chronic refractory prostatitis which is infection‐based, one often cannot be treated effectively

with antibiotics. However, when Detoxamin (EDTA) or other agents to address the biofilms are used, it then

becomes possible to treat these infections with tetracyclines. Patients quickly show functional increases and

decreases in pain other symptoms.

Summary

In chronic Lyme disease, it is often difficult to know which infections are actually responsible for the

persistence of illness. However, in general terms, chronic intracellular infections that change the metabolism

of cells and suppress mitochondrial and other functions will lead to patients remaining in a chronically ill

state. Dr. Nicolson believes that these infections must be aggressively treated. “Similar to chronic Lyme

disease, the current CDC or IDSA recommendations for short‐term treatment of chronic infections are simply

inadequate,”he says.

Dr. Nicolson has found that there is a hierarchy of symptoms that resolve relatively quickly and those that

resolve more slowly when treating Mycoplasma. Gut‐associated phenomenon such as Irritable Bowel

Syndrome (IBS) often resolve quickly. Other systemic signs and symptoms can resolve in an intermediate

period of time from many weeks to many months. Symptoms associated with the central and peripheral

nervous systems such as neuropathy and pain often resolve much more slowly. Skin sensitivity and burning

sensations may take much longer to resolve. Mycoplasma infections do invade nerves, and nerve‐related

symptoms are among the more difficult to resolve.

Dr. Nicolson states “e keep seeing the suppression of information on Mycoplasma and similar intracellular

bacterial infections. The world of Mycoplasma parallels the world of chronic Lyme disease in terms of the

politics involved. Physicians are being persecuted by their medical boards as a result of bad information. It is

important for us to do everything within our power to get rid of harmful, erroneous information about these

diseases. Both Mycoplasma and Borrelia have been manipulated for biological weapons purposes and as a

result, both are politically incorrect to discuss, work on, or do anything about. Until this changes, we won’t

see any real progress.”

Resources

Professor Garth L. Nicolson is the President, Chief Scientific Officer and Research Professor at the Institute for

Molecular Medicine in Huntington Beach, California. Born in 1943 in Los Angeles, Dr. Nicolson received his

B.S. in Chemistry from University of California at Los Angeles in 1965 and his Ph.D. in Biochemistry and Cell

9 Mycoplasma – Often Overlooked In Chronic Lyme Disease

Biology from the University of California at San Diego in 1970. Professor Nicolson has published over 580

medical and scientific papers, edited 15 books, and served on the Editorial Boards of 30 medical and scientific

journals. He is also a Colonel (Honorary) of the U. S. Army Special Forces and a U. S. Navy SEAL (Honorary) for

is work on Armed Forces and veterans’ illnesses. More information on Dr. Nicolson’s work can be found on

te at

h

his web si http://www.immed.org.

The book Project Day Lily is available at http://www.projectdaylily.com/

Scott Forsgren is the editor and founder of BetterHealthGuy.com where he shares his twelve

year journey through a chronic illness only diagnosed as Lyme disease after eight years of

searching for answers. Scott can be reached at Scott@BetterHealthGuy.com.

Additional information on NT Factor® can be found at http://www.ntfactor.com

or http://www.researchednutritionals.com.

Post Edited (Simela) : 9/3/2010 10:43:41 AM (GMT-6)


Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/3/2010 12:25 AM (GMT -6)   

Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 35853
   Posted 9/3/2010 7:30 AM (GMT -6)   
Hi Simela, hope you are doing as good as possible today!!!
The first link didn't work - at least for me!!! :)
Even the mightiest oak tree was once a little nut who held it's ground!!!
May we all find peace along the journey to find healing.
"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP
Trav

Mamyou
Regular Member


Date Joined Aug 2010
Total Posts : 317
   Posted 9/3/2010 7:49 AM (GMT -6)   
First link didn't work for me either.

Like Traveler, I hope you're having a good day. Keep your eyes on that LLMD appointment!!

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/3/2010 10:49 AM (GMT -6)   
Sorry the link doesn't work, I copied and pasted the whole thing above. Not sure why the link does not work, I saved it on my computer after I read the article last night. I KNOW is long, but I hope you will read it--you will be glad you did! You can also find the info on Dr. N's website, that is listed in the article, if you doubt its genuinity (not sure that's a real word--LOL--can't think of a better one)!

I am having a so-so day, thanks for asking. Yesterday was REALLY bad, pain was so severe, I felt I was going into labor! NOT GOOD! Today, much better compared to yesterday. As long as yesterday does not return, I can bear today...

Yes, looking forward to the 16th!!! to meet with my LLMD

Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 35853
   Posted 9/4/2010 5:30 PM (GMT -6)   
Hi Simela!!
Thank you for posting this! It's a good article & I found out some more info on Veterans who have come back ill for my daughters' fiance.

Yes, there is actually a lot of scary things out there for us lymies. It doesn't always affect each & every one of us, fortunately, but none the less the info is out there. I know when I first was on the hunt for all the info I could possibly find on tick-borne infections & what they would mean to me, I found that I was pretty worked up most of the time. It wasn't until I realized that I had to find a way to stop letting this info get to me like that, that I found some relief - so be careful with your health!

I'm not in the least suggesting that you stop your 'research reading', only just a caution of not allowing it to affect your health.
Blessed are we who can laugh at ourselves, for we will never cease to be amused!!!! :)
May we all find peace along the journey to find healing.
"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP
Trav

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/5/2010 4:29 PM (GMT -6)   
Trav:
I know what you are saying, I felt the same way at times. The first time I got sick was nothing, really. I trusted my PCP that 3 wks of abx "cure" the disease. Than months later, I started to feel worse and worse and worse. I asked for another test and another and another and another. He kept telling me the whole time that my tests were false +. Then I came across this forum and others and found out that 3 wks may not be enough to eradicate Lyme. I asked my pcp for all my tests and ran the other way. In the meantime, I realized this is hard to beat. It was hard to get out of bed and face another day realizing I may not be able to get rid of it. I would open my eyes and then close them because the first thing that came to my head was: YOu are sick and you may never be as healthy as you used to, ever again!

Now, I am trying to find out as much as I can and try to beat it. It is me or it! Sticking my head in the sand won't work in my favor, so I must educate myself and learn what may work and try to kill it, or it will kill me! Not easy, but I may have a chance. Staying away from knowledge won't serve me any good. It would also be hard to do that now--I know too much already!

Mamyou
Regular Member


Date Joined Aug 2010
Total Posts : 317
   Posted 9/5/2010 5:53 PM (GMT -6)   
Simela, Thank you for this post. Doesn't surprise me though. I've vented a few times on this forum about cover-ups, so this is just one more. I'm glad I'm the age I am...would hate to be a child starting out in this mess. I agree with Trav (as always), you can't let it all get to you or you'll be worked up all the time. You just have to try and protect yourself and pray health comes because of something you've done RIGHT.

I live in the country and was thrilled to have no cell phone service. I figured that would cut down on radiation. Lo and behold....when I walk out my back door, I now see the red light of the new tower. Everybody rejoiced but me, and I was labeled "dumb".

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/5/2010 7:41 PM (GMT -6)   
Mamyou:
I am NOT letting it get to me! The reason I posted it is so that it may bring some awareness. Mycoplasma IS a common tick infection, yet docs do not check for it. This should be a wake up call for all of us if we are on abx and do not get better. Tests are lousy, but we should watch out for symptoms and treat for other things than Lyme and co-infections. For ex. I found out I also have at least one active virus. Mycoplasma may be a piece of the puzzle for some people and that is the reason I posted this--I did not post it bec. I wanted to vent but hoping that it may help all of us to learn something new.

I will let you know when I wanted to vent, though! LOL I have been feeling a lot better in the past few days!

+Lyme
Veteran Member


Date Joined Apr 2009
Total Posts : 1304
   Posted 9/6/2010 11:48 AM (GMT -6)   
Simela, I appreciate you posting this -- I had done a little research on mycoplasma just over a year ago, when I was first getting into this mess and I let it go, just because it was too much. Just as you and everyone else has said, all this is so overwhelming --- partly because overwhelmed feelings seem to be a part of this disease-- it is a huge part for me ----- and partly because there is so much to see and consider once we've contracted a TBI.

Maybe you aren't, but I AM letting all this get to me. I have meltdowns regularly.

I have not been tested for mycoplasma, so I will request that my Dr do this when I have my next consult. I HATE doxy tho and hope that something else -- like my augmentin -- might be effective against it.

One thing is for sure -- we will NEVER be able to prove what has been done in all this. Never!
Bit 1972: Acute and chronic tonsillitis, UTI, miscarraige, appendicitis, hypoglycemia,  chronic neck pain w/ crushed vertibrae, chronic severe back pain, mitral valve prolapse, depression, resolution?
 
Bit Mother's Day 2007: Lyme, Babesia microti, hypothyroidism, EBV, HHV6, Parvovirus B19, low adrenals &misc other hormones, depression, anxiety, more of the above.

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/6/2010 3:21 PM (GMT -6)   
+Lyme:

I do have horrible days when it gets to me. I realized it is not good to let it get to me--not for me and not for my children, especially for the baby. There were days when I had this feeling I should run away to escape it and leave it behind, somehow.  Sort of crazy, and I realize that now, it was as something inside me was telling me to run away to get away from it--like that would happen!

My personality is that way, I rebound quickly. I have 3 kids. I CAN'T LET IT GET TO ME!

When I was in grad school, this Statistics Professor that I admire most in the intelectual world, always had a quote for us, that he would write on the black board before class. One time the quote was:

"I CAN'T DO IT, I MUST DO IT, I WILL DO IT!"

I apply this concept anytime I am in a dilema. Sure, I was down for a while. But that is over now! Unless I get really really sick (knock on wood), I can deal with it and not let it get to me!  I slow down in my bad days and try to stay calm and +.  Everything I read I use as a weapon to get better, and not to get me down! I MUST keep my stress level to a minimum in order to get better! And I WILL!

Post Edited (Simela) : 9/6/2010 5:39:52 PM (GMT-6)


Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 35853
   Posted 9/7/2010 12:07 PM (GMT -6)   
I'm afraid I may have been mis-understood. I was not in the least saying that it is a good thing for people to stick their head's in the ground when it comes to their health. Heck!! My family is tired of listening to me constantly telling them to be sure they get their OWN copies of at least their blood work!!!

I happen to believe in order to suffer the least, each and every one of us must know as much as our brains can handle about our health situations. That has been the ONLY reason I have gotten as far as I have with improving my health - the docs I've seen sure haven't been very concerned!!!

I just merely wanted to say that some times too much info on the wrong day can sure be a downer & has the possibility to play with one's mind.

So sorry I wasn't more clear on my position.
Blessed are we who can laugh at ourselves, for we will never cease to be amused!!!! :)
May we all find peace along the journey to find healing.
"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP
Trav

Mamyou
Regular Member


Date Joined Aug 2010
Total Posts : 317
   Posted 9/7/2010 12:50 PM (GMT -6)   
There is a difference between a desire to research information (and learn) and how you let it affect you. By all means....learn all you can, when you can and how you can. Just don't let it stress you. We have wonderful minds on this forum.....and that's probably what I appreciate the most. I love gathering information....

I'm glad you're feeling better Simela....there were a few days I was worried about you. By the way...once in awhile I edit for my daughter....did you mean I CAN DO IT, or I CAN'T DO IT????? Just wondered if it was to start with the negative and you talk yourself into the positive?????.... that's the most normal for me.....

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/7/2010 12:52 PM (GMT -6)   
Trav:

I don't think you were misunderstood, I think I still don't have severe side effects as some other people and I attribute it to failure of treatement, not success of it. The reason I feel the way I feel, is I THINK because I am not killing enough bacteria. I take amox 3x day 500 strenght, which I think is my sugar pill--I pretend I am killing the bacteria, and the bacteria pretends it's dead. I am aware of the possibility that I will feel a lot worse when I will be given some real treatement. Dr B recommands amox in much higher doses! I will let you know then , how I will feel about it, but for now, I was really sick for about a week about 2 weeks into the abx treatement, and now I am a lot better. My knees were killing me yesterday, my anckles the day before, wrists, etc etc etc, but it is not constant pain, as it was during that week, it comes and goes, so I can deal with it.

No need to appologize, really--I feel that some people here had experienced much worse symptoms than me! I do not think anyone makes it up, I think their pain and suffering is genuine. Not looking forward to it, but I have this feeling a lot more pain will come my way soon! I will tell you then if I still feel
"I CAN'T DO IT, I MUST DO IT, I WILL DO IT!"

Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 35853
   Posted 9/7/2010 1:30 PM (GMT -6)   
You don't need to apologize to me, Simela!!!
I am a lot like you, I suspect - I HAVE to know!!! I go through the same process of "I can't do this -- awwww POOP!! I have to do that - & finally the last phase of - okay, grab the seat of my pants & say I WILL do this!!! * Sorry about the language* The whole time during that process I am glued to my computer & Google Scholar reading everything that I can comprehend even slightly!!!

I also feel the same as you do - I haven't suffered nearly as much as others here. I haven't been hospitalized - well okay...but only for the removal of some part I obviously didn't really need (tongue in cheek here - I've had my appendix & gb removed & knee surgery on 1 knee), but I haven't had any serious issues by my evaluation - just very long-standing issues.

I just wanted to be sure that there are no hard feeling between you & myself - actually between me & any one else here on this forum. I do really NEED to be here!!

Peace to all...
Trav
Blessed are we who can laugh at ourselves, for we will never cease to be amused!!!! :)
May we all find peace along the journey to find healing.
"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP
Trav

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/7/2010 2:04 PM (GMT -6)   
Trav:

No hard feelings! We all need to be here and help each other. And you helped me so much already and even made me laugh a few times--which I need more of! But I lost my train of thought and can't even remember why you thought you needed to appologize. LOL Anyway, I can't get upset with you because it will soon cool down and I may need help with my kefir!

WHO else can help me with that, but the Kefir master!  ;)

Post Edited (Simela) : 9/7/2010 2:08:34 PM (GMT-6)


Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 35853
   Posted 9/7/2010 4:38 PM (GMT -6)   
LOLOLOLOLOLOL!!!! Kefir Master!!! LOLOLOLOLOLOLOL smilewinkgrin turn smilewinkgrin cool

I can't hardly wait to tell Huuby I'm a MASTER!!!!! cool
Blessed are we who can laugh at ourselves, for we will never cease to be amused!!!! :)
May we all find peace along the journey to find healing.
"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP
Trav

+Lyme
Veteran Member


Date Joined Apr 2009
Total Posts : 1304
   Posted 9/7/2010 7:27 PM (GMT -6)   
Simela, I'm sure I've told you that when I saw the first LLMD, he prescribed two 875 pills, 2X per day -- appx 3500 mg/day. I was concerned that this dose was too high and that he had made a mistake, but I think I figured out that Dr Burr advised a higher dose (or stated it could be much higher) and others on here were on higher dose. That's a whalloping dose, so I'm not stating you should be on that, but perhaps your dose is not high enough.

I convinced myself that that dosage could kill ALL the spirochetes: DEAD, DEAD, DEAD. Because that is a lot of abx. Alas, I guess it killed a lot, but not near enough.

Also, here you will find extremely varying time tables from people, as to when they felt they started herxing and when they started feeling better. So it's all very hard to say.

bucci
Veteran Member


Date Joined May 2006
Total Posts : 1477
   Posted 9/7/2010 11:01 PM (GMT -6)   
Wow!
I can't believe I actually read all of that. But it is true. the more I read ...the more I felt even more hopeless or is it helpless?


just ..doomed..for lack of a better explaination of an emotional experience.

in the end I am still left confused.........IS THERE A TEST FOR THIS? what lab?

and the treatment is antibiotics for life????

or is that the answer for people who have had lyme for years and never knew it?

I am getting worse and can't afford anymore treatment.

and what is the use if nothing really works. this whole scene is so controversial fright from the testing to the treatments on every level.

it can't get any scairier because from what I've seen in last 15 yrs and especially this past 11 months since i found out about the lyme and all the co infections.........it's a death sentence. a living hell. why bother getting pissed ....it is too exhausting.

I know the government has a cure for all this. it has got to get exposed and it will but by that time most of us will have too much damage done. but they have to be stopped from killing off everyone.

I would like to see a list of any politicians who have had lyme in their family and would like to know how they were treated.
the Kennedy's must have gotten bit out at Martha vinyard. what did their doctor say? "don't worry about it?" It's nothing?

there is an inside track on this ....

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/8/2010 8:01 AM (GMT -6)   
Bucci:
I think the doc mentioned the name of the lab in the article. I will read it again in a few days, I don't have any time now, but I will take notes of the different species and the labs he is using for testing. Some good, reliable labs were closed down already. Scary or not, it is better that we learn and tesst for this. Most docs won't test for it. The doc made it part of his life bec. family members had it.

BTW: Bush has lyme. He is listed on wikipedia as a celebrity with Lyme. He did not do anything about changing the status quo! Maybe we should all write him a letter?

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/8/2010 8:05 AM (GMT -6)   
+Lyme:
I know I am not taking enough, but I am breastfeeding. Like I said, this is probably almost a sugar pill, but I would like to continue BF for a few more mo, if I can. Baby is not gettin enough weight and I think she may be sick. He pediatrician said if I BF, she will get my antibodies. I am afraid if I stop, she will get sick. I do suspect is may have lyme, but I pray I am wrong. She seems in pain sometimes, but it may be from teething. I will see what the LLMD says on the 16th. Hey, I would double the dose, but I can't afford to hurt the baby. Amox passes in breast milk

Simela
Veteran Member


Date Joined Aug 2010
Total Posts : 552
   Posted 9/8/2010 8:09 AM (GMT -6)   
Master Trav:

I was never in the hospital for anything, except giving birth... So it is easy for me to feel this way. I am trying to stay positive

Traveler
Forum Moderator


Date Joined May 2007
Total Posts : 35853
   Posted 9/8/2010 9:44 AM (GMT -6)   
Okay Simela!!
turn Now you have to picture me rolling around on th floor, laughing so hard I have tears running down my face and can't hardly breathe!!!!! -- Master Trav - smhair LOL LOL LOL LOL smilewinkgrin scool
Blessed are we who can laugh at ourselves, for we will never cease to be amused!!!! :)
May we all find peace along the journey to find healing.
"Absence of proof is not proof of absence" - Dr. Edwin Masters, great LLMD & researcher -RIP
Trav
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