IgG p41 and IgG p23, could this be Lyme?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

stiles
Regular Member


Date Joined May 2014
Total Posts : 24
   Posted 5/21/2014 2:01 PM (GMT -6)   
I’m a 26 year old male living in Northern VA. I wanted to share some test results with you guys to see if you had any insight for me. I have no recollection of a tick bite, but I did attend several outdoor music events last year and I do have a cat (indoor only).

My test results:

December 2013 - Western Blot with LabCorp: All bands were negative.
April 2014 - Western Blot with LabCorp: Retested and found the following:

IgG p41 Ab. – Present Abnormal
IgG p23 Ab. – Present Abnormal

All other IgG and IgM results were negative.


I’ve listed my symptoms below. I’ve had these for about 7 months, some days are worse than others.

Chronic off balance / heavy head
Chronic spacey feeling in head
Chronic chest pain on the right side (worse when breathing deep or weight lifting)
Lightheadedness
Exhaustion after walking short distances
Rocking / Swaying feeling in body
Vision feels off, almost dreamlike
Vision also feels sometimes like there’s too much information (sensory overload)
Vision feels lagged, like it takes time for what I’m seeing to register in my brain
Headaches come and go
Pressure behind the eyes comes and goes as well
Overall body fatigue (notice it mainly in my legs)
Shortness of breath
Clumsy while walking
Tight neck / middle of back / lots of popping and cracking
Face feels flush like I have a fever but I don’t
Intense nausea and disorientation
Daily skin peeling on hands/hives on hands

I’m currently attempting to make an appointment with an LLMD in VA for next week. I’m hoping to have an Igenex blood test run. Could those ‘Present Abnormal’ IgG bands be indicative of Lyme? Does anyone have any advice for me when I visit the LLMD? I don’t understand how those bands were absent just 4 months earlier even though I was symptomatic?

I keep being told that I’m fine which is making me feel crazy. Any thoughts?
Thanks so much in advance, this has been a really tough year.

Steve

pictureofhealth
Regular Member


Date Joined Dec 2013
Total Posts : 482
   Posted 5/21/2014 2:37 PM (GMT -6)   
First of all welcome to this forum, I hope you find it as helpful as I do.
I had WB bands 23+ & 41+. When I found a LLND and told her about my symptoms and showed her my tests, she started treatment right away. I read somewhere that band #23 is most likely lyme. Hopefully, you will get an appt. with a LLMD soon and get some answers. Keep us posted.

stiles
Regular Member


Date Joined May 2014
Total Posts : 24
   Posted 5/21/2014 3:01 PM (GMT -6)   
pictureofhealth said...
First of all welcome to this forum, I hope you find it as helpful as I do.
I had WB bands 23+ & 41+. When I found a LLND and told her about my symptoms and showed her my tests, she started treatment right away. I read somewhere that band #23 is most likely lyme. Hopefully, you will get an appt. with a LLMD soon and get some answers. Keep us posted.


Thanks so much for the response and the warm welcome. I managed to get an appointment for next Wednesday, so I will definitely be sharing my experience from that visit next week.

I too have read that #23 is pretty specific to Lyme after a few google searches. I just don't really understand why it's showing up on IgG and not IgM. Was your Lyme confirmed with more testing (IGeneX maybe)?

Thanks again!

stacestar
Veteran Member


Date Joined Jan 2014
Total Posts : 532
   Posted 5/21/2014 3:14 PM (GMT -6)   
Here is something I read once and saved from something Dr. Joe B.(the lyme expert) wrote. It was in like a slide/power point thing that I found online.
He wrote:

"Conclusion: IgG 18, 41, and 58 kDa
-statistically associated with tick-borne disease

IgG and IgM 23-25, 31, 34, 39, 83-93
-Highly specific markers for lyme disease "

He also mentioned other bands that are not specific to lyme saying that, but I left that part out since those weren't ones you mentioned.

With that information and your symptoms, I'd say it's highly likely it's a lyme infection.
Good thing to make the llmd appt.

As far as why they were negative before, I don't the answer, but have heard that sometimes it can take time for the bands to show up positive. also, in that same website information that I quoted from Dr. Joe B he also said, on another page of his info., the following:

"…if a positive IgG is present it will generally indicate one of the following things:

one has a healthy immune system and is fighting Bb well."

The other thing he said it indicated is that the person didn't have lyme i.e. was exposed but is asymptomatic or doesn't have it anymore. But if one (like yourself) is feeling symptoms than of course that's not asymptomatic.

It can be hard to make sense of it all, but I'm sure a good llmd can help you figure it out. I hope you can be feeling better soon!

stiles
Regular Member


Date Joined May 2014
Total Posts : 24
   Posted 5/21/2014 5:50 PM (GMT -6)   
stacestar said...
Here is something I read once and saved from something Dr. Joe B.(the lyme expert) wrote. It was in like a slide/power point thing that I found online.
He wrote:

"Conclusion: IgG 18, 41, and 58 kDa
-statistically associated with tick-borne disease

IgG and IgM 23-25, 31, 34, 39, 83-93
-Highly specific markers for lyme disease "

He also mentioned other bands that are not specific to lyme saying that, but I left that part out since those weren't ones you mentioned.

With that information and your symptoms, I'd say it's highly likely it's a lyme infection.
Good thing to make the llmd appt.

As far as why they were negative before, I don't the answer, but have heard that sometimes it can take time for the bands to show up positive. also, in that same website information that I quoted from Dr. Joe B he also said, on another page of his info., the following:

"…if a positive IgG is present it will generally indicate one of the following things:

one has a healthy immune system and is fighting Bb well."

The other thing he said it indicated is that the person didn't have lyme i.e. was exposed but is asymptomatic or doesn't have it anymore. But if one (like yourself) is feeling symptoms than of course that's not asymptomatic.

It can be hard to make sense of it all, but I'm sure a good llmd can help you figure it out. I hope you can be feeling better soon!


Thank you for the very informative post. IgG vs IgM is making a bit more sense to me now. I'm wondering how likely the IgG tests were false positives though? I guess it's better to just wait and see what the LLMD says next week rather than trying to guess myself. Either way, thanks a tun. I'll update this thread after my visit.

stiles
Regular Member


Date Joined May 2014
Total Posts : 24
   Posted 5/29/2014 12:24 PM (GMT -6)   
As promised I’m back to give an update after seeing an LLMD. She didn’t really say one way or the other if she thinks this is most likely Lyme, but I’m having a few IGeneX tests run. These specifically:

5090 - Complete Co-Infection Panel
188 - Lyme Western Blot IgM
189 - Lyme Western Blot IgG
720 - B. duncani IgG & IgM Antibody

She gave me a few instructions to follow which I will be starting this weekend:

Start a yeast free diet and the following supplements:
- Theralac, one tablet daily
- Co-enzyme Q10 50mg, one tablet daily. After one week increase the dose to 100mg daily.
- Chlorella 500mg, 2 tablets daily.
- Propel packets, 2-3 daily.
- Vitamin C, 1000mg daily
- Vitamin D, 2000unis once daily

Does anyone have any thoughts on these supplements, or the yeast free diet?

I’m having a pretty tough time emotionally this week dealing with everything. Paying out of pocket for the IGeneX tests was more than I was hoping it would be, but I think it's worth it. I’m noticing lately just so much exhaustion and fatigue in my body, especially after walking short distances. I'll update again after my blood work comes back. Thanks again everyone.

lyme47031
New Member


Date Joined Jul 2013
Total Posts : 15
   Posted 5/30/2014 6:38 AM (GMT -6)   
I too had similar test results.  I was Igm p 23 and Igg P41 positive on a western blot test from a local hospital.  With these results and my symptoms, my LLMD said I had definitely been exposed at some point to the lyme bacteria.
 
Looking back, I'm thinking it may have been 10 years ago.  I had some weird symptoms for months at a time and they would just disappear.  In Spring of 2012, everything hit me at once and I was pretty sick.  Feeling a lot better now but I still have some symptoms I'm trying to get rid of.
 
Anyway, I just wanted to mention my test results.  From what I've read and talking with some very knowledgeable people on this forum, most people are not CDC positive on the western blot. 
 
I hope you find out something with your test results.  Even though my doctor said I'd been exposed, I still wish I had sent a blood sample to IGenex..........take care.

tickbite666
Veteran Member


Date Joined Mar 2014
Total Posts : 1352
   Posted 5/30/2014 10:43 AM (GMT -6)   
Stiles,

The supplement list looks good. But I also recommend adding Milk Thistle, and maybe Fish Oil.

stiles
Regular Member


Date Joined May 2014
Total Posts : 24
   Posted 6/25/2014 7:41 AM (GMT -6)   
Hi guys, I finally spoke with my LLMD yesterday and they gave me a few verbal results over the phone from my IGeneX testing. I'll be receiving the full results in the mail later this week and have a follow up with her on the 9th of July.

31 IgM Positive
83/93 IgM Positive
38 IgM Inconclusive

41 IgG Positive
23 IgG Negative (was positive on last my western blot).

My LLMD said she thinks this is why i'm symptomatic. I'm trying to google these bands, but I'm really not sure what to make of the results. Any input would be greatly appreciated. Thanks :)

Harrison2014
New Member


Date Joined Dec 2014
Total Posts : 1
   Posted 12/27/2014 10:27 PM (GMT -6)   
Stiles, wanted to see if you had any updates from your last post from June?

I have very similar symptoms and also was Paiute for kpg 23 and 41

DR put me on 30 days of doxy twice a day. Which is coming to an end in the next couple days. Feeling much better but not a 100%. Will be seen if it's temporary or something more permanent.

Also have appt with lld in 2.5 weeks. Anyhow, wanted to see if you've made any progress or have any suggestions.
New Topic Post Reply Printable Version
Forum Information
Currently it is Sunday, October 22, 2017 10:16 PM (GMT -6)
There are a total of 2,885,874 posts in 316,649 threads.
View Active Threads


Who's Online
This forum has 157751 registered members. Please welcome our newest member, engineer1234.
364 Guest(s), 7 Registered Member(s) are currently online.  Details
Africa99, clo2014, cashlessclay, The Dude Abides, Fairwind, shad0w69, lucy147


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2017 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer