I did five days of solumedrol last spring. The IV port was fine. They wrap it in a very secure stretchy sleeve to keep it from being in the way. My home health care nurse gave me the option to have the IV started each day or to leave the port in. I chose to leave it in rather than to play "find the vein" for five days in a row. I was much too ill from the flare to work. I wasn't up for doing too much. My worst side effect was that the first night I had trouble sleeping. After that, it was the horrible acid reflux that you get. I did not taper off with an oral steroid (that is supposed to be really helful) so coming down from five days of the IV steroid was a bit rough. The solumedrol does make you feel pretty energetic but I was not walking too well so it was hard to use all that extra energy. I would only do the solumedrol again if I flared was as bad as last spring. Again, I was nearly completely numb from the waist down and I could not walk too well. I had deep numbness in my left leg and very bad spasticity. I basically was out of commission for about 3 weeks and it took about 3 months before it all settled enough to know what residuals I would be left with. The solumedrol does not reduce disability, it only treats symptoms. You have the option of NOT having solumedrol as it is supposed to be for symptom relief and it doesn't treat MS or keep it from doing damage.
Love and prayers,