Severe Coldness/Shivering reaction to Copaxone???

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Lefty85
Regular Member


Date Joined Apr 2009
Total Posts : 87
   Posted 6/12/2009 10:08 PM (GMT -6)   
My boyfriend has MS and has been taking injections of copaxone for several months now.  He hadn't taken it for about the last week or so (which I was unaware of until tonight).  Other than some pain and stinging at the injection site, he'd never had any reaction to copaxone before.  However, earlier tonight, about 45 minutes or so after taking his shot, he started shivering and shaking violently and complaining that he was extremely cold.  He was in bed with several blankets and I had him take some tylenol because I thought his forehead felt warm and that he might have a fever.  After about a half an hour, the shivering ceased, and about 10-15 minutes after that he said he didn't feel so cold anymore.  He finally just fell asleep about 10 minutes ago.  I was just wondering if anyone else has ever had a reaction like this to copaxone.  From what I have read it's my understanding that most people have little to no reaction to it.  What I find strange is that he never had a reaction when he took it before, so why would it just start all of a sudden?  He is also currently taking Vicodin and Flexeril for a back injury, which is recent.  I don't know if the other medications could have caused some type of reaction or not.  After he started calming down tonight he told me that he had had a similar reaction the very first time he'd taken avonex, which he was treated with when he was first diagnosed.  I know that it is much more common to become sick from avonex, but I am guessing it is also possible with copaxone since it's the same type of medication.  I'm just not sure if he should continue taking the copaxone or if we should contact his doctor and see about something different.  If anyone has ever experienced anything like this and has any reccomendations I would greatly appreciate it.  I hope I've explained this all okay... I'm still pretty upset and worried.  Anyway, thanks in advance.
 
SaraBeth
Fibromyalgia, Depression, Anxiety
***********
Amytriptiline, Flexeril (PRN), Percocet (PRN), Ambien (PRN at bedtime), B12
***********
Be not afraid of going s l o w l y, be afraid only of standing still.
 
 
 
 
 
                                                                                  


Gretchen1
Forum Moderator


Date Joined Jan 2007
Total Posts : 3539
   Posted 6/12/2009 10:24 PM (GMT -6)   
Hey SaraBeth,
 
Copaxone is a very different drug from avonex.  Avonex is an interferon that has the very noted side effect of flu like symptoms.  Copaxone is not at all known for this side effect.  We have had members react badly to copaxone however.  We have members that can't tolerate it.  This is rare but it does happen.  With copaxone there is the chance of an IPIR (immediate post injection reaction).  It is immediate so this doesn't fit the description you have posted of your boyfriend's cold shivers.  I think (but I am not sure) that we have had a member post about this same sort of deal with copaxone.  Obviously you would want your boyfriend to call his neuro about this.  You can also call shared solutions (TEVA.....the co that makes copaxone) and ask them about this as well. 
 
What made him stop taking it for a week?  Good luck.  I hope this doesn't happen again and that the copaxone works to slow progression for him.  I have been on it for about two and a half years now.  I have never had that reaction and I do think it is a decent therapy for MS. 
Gretchen       co-moderator MS board       diagnosed with MS July 2006
 
I have no lesions on my soul and so I will live with no limits.


Lefty85
Regular Member


Date Joined Apr 2009
Total Posts : 87
   Posted 6/13/2009 9:48 AM (GMT -6)   
Thank you, Gretchen. He is fine this morning. He woke up again in the middle of the night and was really overheated. I'm pretty certain he was running a fever, although I didn't check his temperature. The reason he stopped taking Copaxone for about a week is because he has a really bad back injury right now. He has to go to the chiropractor every day and he's been in severe pain. He said that taking the shot would've been too much to deal with-- because he usually gets pain and stinging at the injection site. I've been at work in the evenings when he usually takes it, so I didn't know that he had stopped. Fortunately, it has been about two or three months since his MS has bothered him at all. I will try to get him to call TEVA. They were very helpful with showing him how to do his injections and with promptly getting him a new auto-injector whenever his first one wasn't working right. He doesn't really care for his neurologist, but his old one retired and there are very few of them in the area. The one he sees is about an hour away. Hopefully I can convince him to call. Sometimes he is stubborn, especially if he thinks it's going to end up costing more money. I always tell him that if it's for his health I will do whatever it takes to get him what he needs and that he doesn't need to worry, but of course he still does. I just hope that if he continues copaxone that it doesn't keep causing him the same problem.
Fibromyalgia, Depression, Anxiety
***********
Amytriptiline, Flexeril (PRN), Percocet (PRN), Ambien (PRN at bedtime), B12
***********
Be not afraid of going s l o w l y, be afraid only of standing still.
 
 
 
 
 
                                                                                  


Gretchen1
Forum Moderator


Date Joined Jan 2007
Total Posts : 3539
   Posted 6/13/2009 10:27 AM (GMT -6)   
I hope he can continue with the copaxone.  Missing a week may cause a flare in a few weeks.  It takes 6 months to a year for copaxone to do it stuff.  It has to be taken regularly.  I wish you both the best of luck.
Gretchen       co-moderator MS board       diagnosed with MS July 2006
 
I have no lesions on my soul and so I will live with no limits.

New Topic Post Reply Printable Version
Forum Information
Currently it is Thursday, October 19, 2017 7:34 PM (GMT -6)
There are a total of 2,884,467 posts in 316,492 threads.
View Active Threads


Who's Online
This forum has 157614 registered members. Please welcome our newest member, fwef48489ui0.
437 Guest(s), 15 Registered Member(s) are currently online.  Details
countingstarsx, Lapis_29, netsavy006, countess18, Jerry L., IamCurious, dacarte3, Mamacat313, Tick41, Girlie, BillyBob@388, searchinginla, garyi, (Seashell), Lanie G


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2017 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer